Coherent Behavior and the Bound State of Water and K(+) Imply Another Model of Bioenergetics: Negative Entropy Instead of High-energy Bonds [0.03%]
相干行为和水与K⁺的束缚态表明生物能量模型不同:负熵而不是高能键
Laurent Jaeken,Vladimir Vasilievich Matveev
Laurent Jaeken
Observations of coherent cellular behavior cannot be integrated into widely accepted membrane (pump) theory (MT) and its steady state energetics because of the thermal noise of assumed ordinary cell water and freely soluble cytoplasmic K(+)...
Biochemical and computational approaches to improve the clinical treatment of dopa decarboxylase-related diseases: an overview [0.03%]
改善多巴脱羧酶相关疾病临床治疗的生化和计算方法:综述
Barbara Cellini,Riccardo Montioli,Elisa Oppici et al.
Barbara Cellini et al.
Dopa decarboxylase (DDC) is a pyridoxal 5'-phosphate (PLP)-dependent enzyme that by catalyzing the decarboxylation of L-Dopa and L-5-hydroxytryptophan produces the neurotransmitters dopamine and serotonin. The functional properties of pig k...
Characterization of Carotenoid-protein Complexes and Gene Expression Analysis Associated with Carotenoid Sequestration in Pigmented Cassava (Manihot Esculenta Crantz) Storage Root [0.03%]
彩色木薯(木薯栽培种)贮藏根类胡萝卜素蛋白复合物的表征及类胡萝卜素富集相关基因表达分析
Luiz Joaquim Castelo Branco Carvalho,John Lippolis,Songbi Chen et al.
Luiz Joaquim Castelo Branco Carvalho et al.
Carotenoid-protein complex (CPC) was isolated from chromoplast-enriched suspensions of cassava storage root (CSR) using size exclusion chromatography and characterized. Peptide sequences (LC_MS/MS spectrum) obtained from CPC and their corre...
Transcriptional and secretomic profiling of epidermal cells exposed to alpha particle radiation [0.03%]
α粒子照射下表皮细胞的转录与分泌组学特征分析
Vinita Chauhan,Matthew Howland,Hillary Boulay Greene et al.
Vinita Chauhan et al.
Alpha (α)-particle emitters are probable isotopes to be used in a terrorist attack. The development of biological assessment tools to identify those who have handled these difficult to detect materials would be an asset to our current fore...
Model of Abnormal Chromophore-Protein Interaction for Е181К Rhodopsin Mutation: Computer Molecular Dynamics Study [0.03%]
E181K视紫红质突变模型的异常色素-蛋白相互作用:计算机分子动力学研究
Tatyana Feldman,Mikhail Ostrovsky,Kholmirzo Kholmurodov et al.
Tatyana Feldman et al.
The interaction of the 11-cis-retinal chromophore with the surrounding amino acid residues in the chromophore center of the rhodopsin protein has been investigated for the Е181К mutant form using molecular dynamics simulation. A comparati...
Esin Eren,Necat Yilmaz,Ozgur Aydin
Esin Eren
Plasma high-density lipoprotein cholesterol(HDL-C) levels do not predict functionality and composition of high-density lipoprotein(HDL). Traditionally, keeping levels of low-density lipoprotein cholesterol(LDL-C) down and HDL-C up have been...
Histidine 117 in the His-Gly-Ser-Asp motif is Required for the Biochemical Activities of Nucleoside Diphosphate Kinase of Mycobacterium smegmatis [0.03%]
鸟苷二磷酸激酶的生化活性需要His-Gly-Ser-Asp基序中的组氨酸117残基:米氏.smegmatis的例子
Muthu Arumugam,Parthasarathi Ajitkumar
Muthu Arumugam
Nucleoside diphosphate kinase (NDK), which is widely conserved in both prokaryotes and eukaryotes, maintains a balanced pool of nucleotide triphosphates and their deoxy derivatives. NDKs from bacterial and other systems contain the conserve...
Myricetin Inhibits Islet Amyloid Polypeptide (IAPP) Aggregation and Rescues Living Mammalian Cells from IAPP Toxicity [0.03%]
芸香苷抑制胰岛淀粉样多肽(IAPP)聚集并解救IAPP毒性损伤的哺乳动物细胞
Casey Zelus,Ayano Fox,Anastasia Calciano et al.
Casey Zelus et al.
The aggregation of the amyloidogenic polypeptide IAPP (Islet Amyloid Polypeptide, amylin) is believed to play a direct role in the death of pancreatic β-islet cells in type II diabetes. Preventing the initial aggregation event of IAPP is o...
Lin Feng,Arulmani Manavalan,Manisha Mishra et al.
Lin Feng et al.
Tianma is a traditional Chinese medicine (TCM) often used for the treatment of hypertension and heart diseases. To elucidate the function of tianma at the molecular level, we investigated the effect of tianma on vascular functions and aorti...
Effect of peppermint oil on serum lipid peroxidation and hepatic enzymes after immobility stress in mice [0.03%]
薄荷油对固定应激小鼠血清脂质过氧化和肝酶的影响
Abdoljalal Marjani,Reza Rahmati,Azad Reza Mansourian et al.
Abdoljalal Marjani et al.
This study was undertaken to determine the influences of various doses of peppermint oil on the hepatic en-zymes, alanine transaminase, apartate tranaminase, alkaline phosphotase and gamma glutamyl transferase and the level of malondialdehy...