Miki Watanabe,Shuisong Ni,Amy L Lindenberger et al.
Miki Watanabe et al.
High-mobility group A1 (HMGA1) non-histone chromatin architectural transcription factors regulate gene expression, embryogenesis, cell differentiation, and adaptive immune responses by binding DNA and other transcription factors. HMGA1 has ...
Phosphorylation of Tip60 Tyrosine 327 by Abl Kinase Inhibits HAT Activity through Association with FE65 [0.03%]
Abl激酶通过FE65介导的相互作用磷酸化乙酰转移酶Tip60酪氨酸327位点抑制其转录活性
Sung Hwa Shin,Sang Sun Kang
Sung Hwa Shin
The transfer of acetyl groups from acetyl coenzyme A to the ε amino group of internal lysine residues is catalyzed by Tip60, which is in the MYST family of nuclear histone acetyltransferases (HATs). The tyrosine phosphorylation of Tip60 se...
Effects of redox state on the efficient uptake of cell permeable Peptide in Mammalian cells [0.03%]
氧化还原状态对哺乳动物细胞中穿膜肽高效摄取的影响
Shayne Squires,Elisabeth Christians,Michael Riedel et al.
Shayne Squires et al.
We investigated whether a cell-penetrating peptide linked via a disulfide bond to a fluorophore-labeled cargo peptide can be used to interrogate changes in cellular redox state. A fluorescence resonance energy transfer (FRET) pair was const...
Activation Energy Calculations for Formamide-TiO2 and Formamide-Pt Interactions in the Presence of Water [0.03%]
含水条件下甲酰胺与TiO2和Pt相互作用的活化能计算
E Dushanov,Kh Kholmurodov,K Yasuoka
E Dushanov
Formamide contains the four elements (C, H, O, and N) most required for life and it is attractive as a potential prebiotic starting material for nucleobase synthesis. In the presence of catalysts (for example, TiO2) and with moderate heatin...
Different redox response elicited by naturally occurring antioxidants in human endothelial cells [0.03%]
天然抗氧化剂在人血管内皮细胞中的不同还原作用响应
Roberta Giordo,Annalisa Cossu,Valeria Pasciu et al.
Roberta Giordo et al.
Evidences that higher natural antioxidant (NA) intake provides protection against cardiovascular disease (CVD) are contradictory. Oxidative-induced endothelial cells (ECs) injury is the key step in the onset and progression of CVD and for t...
Nitric oxide and its metabolites in the critical phase of illness: rapid biomarkers in the making [0.03%]
一氧化氮及其代谢产物在疾病关键阶段的快速生物标志物作用
Asad I Mian,Mayank Aranke,Nathan S Bryan
Asad I Mian
The potential of nitric oxide (NO) as a rapid assay biomarker, one that could provide a quantum leap in acute care, remains largely untapped. NO plays a crucial role as bronchodilator, vasodilator and inflammatory mediator. The main objecti...
Comparison of Glycemic Excursion in Patients with New Onset Type 2 Diabetes Mellitus before and after Treatment with Repaglinide [0.03%]
利西拉肽与甘精胰岛素治疗新诊断的2型糖尿病患者疗效和安全性的对比研究
Sharabeh Hezarkhani,Shokufeh Bonakdaran,Reza Rajabian et al.
Sharabeh Hezarkhani et al.
Due to industrialization and sedentary life, incidence of type 2 diabetes (DM2) is increasing seriously. Repaglinide is a glucose reducing agent that predominantly reduces post-prandial glucose. Continuous glucose monitoring system (CGMS) m...
Age related metabolic syndrome among hemodialysis patients in gorgan, iran [0.03%]
伊朗戈尔甘地区维持性血液透析患者与年龄相关的代谢综合征
Abdoljalal Marjani,Mohammad Moujerloo,Sharabeh Hezarkhani
Abdoljalal Marjani
People with metabolic syndrome are at high risk for developing cardiovascular disease. The present study aimed to determine the age related metabolic syndrome of hemodialysis patients. The biochemical parameters and demographic information ...
The involvement of xanthohumol in the expression of annexin in human malignant glioblastoma cells [0.03%]
蛇麻黄素通过作用于星形胶质细胞源性因子1促进人类恶性胶质瘤细胞凋亡中的新机制研究
M Festa,M Caputo,C Cipolla et al.
M Festa et al.
Glioblastoma multiforme (GBM) is the most common malignant and resistant tumor of the central nervous system in humans and new therapeutic strategies are urgently required. Recently, we have shown that the potential chemotherapeutic polyphe...
The Stimulatory Mechanism of Hepatitis C Virus NS5A Protein on the NS5B Catalyzed Replication Reaction In Vitro [0.03%]
丙型肝炎病毒NS5A蛋白对NS5B催化的复制反应的调控机制研究
Elizabeth M Quezada,Caroline M Kane
Elizabeth M Quezada
The Hepatitis C Virus RNA dependent RNA polymerase, NS5B, is stimulated by the NS5A protein in vitro. To explore this stimulatory mechanism, we compared the activity of a mutant of NS5B containing a deletion of the β-loop region with that ...