Constitutive Expression of GATA4 Dramatically Increases the Cardiogenic Potential of D3 Mouse Embryonic Stem Cells [0.03%]
GATA4的组成型表达可显著提高D3小鼠胚胎干细胞向心肌分化的潜能
Lillian L Laemmle,Justus B Cohen,Joseph C Glorioso
Lillian L Laemmle
The transcription factor GATA binding protein 4 (GATA4) is a vital regulator of cardiac programming that acts by inducing the expression of many different genes involved in cardiomyogenesis. Here we generated a D3 mouse embryonic stem cell ...
Bradley Neddenriep,Anastasia Calciano,Daniel Conti et al.
Bradley Neddenriep et al.
The misfolding and aggregation of proteins into amyloid has been linked to a variety of age-related diseases. Aggregation of proteins, such as Aβ in Alzheimer's disease and Islet Amyloid Polypeptide (IAPP, amylin) in type 2 diabetes, appea...
Synthesis and Purification of Highly Hydrophobic Peptides Derived from the C-Terminus of Amyloid β-Protein [0.03%]
来源于淀粉样蛋白β-蛋白C端的高疏水性肽的合成与纯化
M M Condron,B H Monien,G Bitan
M M Condron
Some biotechnological inventions involve expensive, sophisticated machines. Others are relatively simple innovations that nevertheless address, and solve difficult problems. Synthesis and purification of highly hydrophobic peptides can be a...