Fibulin-5, an integrin-binding matricellular protein: its function in development and disease [0.03%]
纤维蛋白5是一种整合素结合细胞外基质蛋白：其在发育和疾病中的作用
Hiromi Yanagisawa,Marie K Schluterman,Rolf A Brekken
Hiromi Yanagisawa
Interactions between the extracellular matrix (ECM) and cells are critical in embryonic development, tissue homeostasis, physiological remodeling, and tumorigenesis. Matricellular proteins, a group of ECM components, mediate cell-ECM intera...
Thrombopoietic-mesenchymal interaction that may facilitate both endochondral ossification and platelet maturation via CCN2 [0.03%]
可能通过CCN2促进软骨内骨化和血小板成熟的生血基质相互作用
Kumi Sumiyoshi,Satoshi Kubota,Rika A Furuta et al.
Kumi Sumiyoshi et al.
CCN2 plays a central role in the development and growth of mesenchymal tissue and promotes the regeneration of bone and cartilage in vivo. Of note, abundant CCN2 is contained in platelets, which is thought to play an important role in the t...
Susan Amanda Lund,Cecilia M Giachelli,Marta Scatena
Susan Amanda Lund
Osteopontin (OPN) is a matricellular protein that mediates diverse biological functions. OPN is involved in normal physiological processes and is implicated in the pathogenesis of a variety of disease states, including atherosclerosis, glom...
Thrombospondins in the heart: potential functions in cardiac remodeling [0.03%]
心脏中的血小板源性生长因子：在心脏重塑中的潜在作用
Mark W M Schellings,Geert C van Almen,E Helene Sage et al.
Mark W M Schellings et al.
Cardiac remodeling after myocardial injury involves inflammation, angiogenesis, left ventricular hypertrophy and matrix remodeling. Thrombospondins (TSPs) belong to the group of matricellular proteins, which are non-structural extracellular...
Connective tissue growth factor (CCN2, CTGF) and organ fibrosis: lessons from transgenic animals [0.03%]
连接组织生长因子(CCN2,CTGF)与器官纤维化：转基因动物模型的启示
David R Brigstock
David R Brigstock
In recent months, four different systems have been reported in the literature in which CCN2 transgenes were individually expressed in podocytes, hepatocytes, cardiomyocytes or respiratory epithelial cells to achieve overexpression in, respe...
Paul Bornstein
Paul Bornstein
Getting to the heart of the matter: CCN2 plays a role in cardiomyocyte hypertrophy [0.03%]
直击要害：CCN2在心肌细胞肥大中的作用
Andrew Leask
Andrew Leask
Connective tissue growth factor (CTGF/CCN2) is overexpressed in diabetes. Diabetic rats possess myocardial and cardiomyocyte hypertrophy. In a recent report, Wang and colleagues (Am J Physiol Cell Physiol. 2009 Jul 22. [Epub ahead of print]...