A multi-band spatial asymmetry convolutional neural network for EEG-based emotion recognition [0.03%]
一种基于EEG的情感识别的多频段空间不对称卷积神经网络
Mengchen Liu,Sha Wang,Qun He et al.
Mengchen Liu et al.
Emotion recognition is an important component for enabling machines to perceive and respond to human emotions. Existing electroencephalogram (EEG)-based emotion recognition methods often rely on single-band signals or purely spatial represe...
Abnormal functional lateralization and cooperation in primary angle-closure glaucoma correlate with cell type-specific transcriptional signatures [0.03%]
原发性闭角型青光眼异常的功能侧化和协同作用与细胞类型特异性转录特征相关
Jing-Wen Qiu,Yuan-Zhi He,Si-Xian Li et al.
Jing-Wen Qiu et al.
Background: Primary angle-closure glaucoma (PACG) damages retinal ganglion cells (RGCs) and is associated with neurodegeneration. This study used resting-state functional magnetic resonance imaging (fMRI) to analyze hemis...
The emerging role of NADPH oxidases (NOX) in Alzheimer's disease pathogenesis [0.03%]
NADPH氧化酶（NOX）在阿尔茨海默病发病机制中的作用不容忽视
Anuradha Yadav,Harkomal Verma,Sakshi Kumari et al.
Anuradha Yadav et al.
Alzheimer's disease (AD) is a slow-progressing neurodegenerative disease, mainly characterized by the accumulation of amyloid beta (Aβ) plaques and intracellular hyperphosphorylated Tau protein, along with the generation of free radicals. ...
Early functional disconnection of the basal forebrain-hippocampal system predicts memory impairment in amnestic mild cognitive impairment [0.03%]
颞叶内侧型轻度认知障碍患者海马基底前脑功能脱偶联现象及其预测记忆衰退的作用
Juan-Juan Lu,Zhi-Jie Xu,Jie Ma et al.
Juan-Juan Lu et al.
While central remodeling in amnestic mild cognitive impairment (aMCI) is well documented, prevailing studies emphasize whole-brain networks or undirected functional connectivity, largely neglecting specific neuromodulatory systems. We there...
Trifluoro-icaritin attenuates neuropathic pain-associated anxiety-like behaviors and hippocampal oxidative stress in rats [0.03%]
trifluoro-icaritin减轻大鼠神经病理性疼痛相关的焦虑样行为和海马氧化应激
Weiwei Li,Fangting Luo,Dandan Jia et al.
Weiwei Li et al.
Neuropathic pain is frequently accompanied by anxiety-like symptoms. Trifluoro-icaritin (ICTF), an icaritin derivative with reported central nervous system activity, has analgesic and anti-inflammatory effects, but its actions in neuropathi...
In vivo evaluation of the dual MOP/NOP agonist AT121: a potent analgesic that delays opioid tolerance and offers a superior withdrawal suppression profile to methadone [0.03%]
AT121的体内评价：一种能延缓阿片类药物耐受性产生的强效镇痛剂，并且其戒断症状抑制谱优于美沙酮
Baraa E Elawy,Loai Aljerf,Shaza A Allaham et al.
Baraa E Elawy et al.
To evaluate the in vivo analgesic efficacy, tolerance liability, and dependence-modulating potential of AT121, a dual μ-opioid (MOP)/nociceptin (NOP) partial agonist, compared with morphine in Wistar rats. Male Wistar rats (n = 264) underw...
An updated patent review of mGlu5 negative allosteric modulators (2018 - present) [0.03%]
2018年以来国际代谢型谷氨酸受体5负向变构调节剂专利分析
Manka Marycleopha
Manka Marycleopha
Metabotropic glutamate receptor subtype 5 (mGlu5) is an important regulator of excitatory neurotransmission and remains a therapeutic target for neuropsychiatric and neurological disorders, including substance use disorders, depression, Fra...
Excessive training alters hippocampal tyrosine hydroxylase and dopamine homeostasis in mice [0.03%]
过度训练会改变小鼠海马多巴胺稳态和酪氨酸羟化酶表达
Alisson Luiz da Rocha,João Pedro Floriano,Ana Paula Pinto et al.
Alisson Luiz da Rocha et al.
Excessive training, defined by repeated high-intensity exercise with insufficient recovery, leads to persistent fatigue, performance decline, and mood alterations. Monoaminergic signaling, particularly serotonin and dopamine, is crucial for...
Synergistic EEG signal processing for brain-computer interfaces using hybrid MothCray optimization and deep learning [0.03%]
基于混合优化和深度学习的脑计算机接口协同EEG信号处理方法研究
Annu Kumari,Damodar Reddy Edla,Dharavath Ramesh et al.
Annu Kumari et al.
Electroencephalography (EEG) based brain-computer interface (BCI) systems require optimal channel selection to achieve high signal quality, reduced setup complexity, and robust usability. This study introduces a comprehensive signal-process...
Low-dose ionizing radiation and cognitive function: evidence, mechanisms, and controversies [0.03%]
低剂量电离辐射与认知功能：证据、机制和争议
Yuqiao Wang,Weiwei Su,Tao Wang et al.
Yuqiao Wang et al.
Humans are chronically exposed to ionizing radiation. Natural background radiation is generally harmless, yet potential risks arise from nuclear accidents, accidental medical irradiation, and high-background-radiation regions. The effects o...