PACAP in Parkinson's disease: A multifunctional neuropeptide at the crossroad of autophagy, inflammation, and metabolic repurposing [0.03%]
Manal Ewaiss Hassan,Hayder M Al-Kuraishy,Mohamed N Fawzy et al.
Manal Ewaiss Hassan et al.
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the accumulation of α-synuclein, mitochondrial dysfunction, and chronic neuroinflammation. In this complex pathology, pituitary adenylate cyclase-activat...
Alyson P Blount,Laurie P Sutton
Alyson P Blount
Targeting the kappa opioid receptor (KOR) system has emerged as a potential alternative to current analgesics, however, advancing the therapeutic development of KOR requires further elucidation of its intracellular signaling events and modu...
Antidepressant-like activity of JZ-1201 in male rodents: a novel selective 5-HT/NE reuptake inhibitor and 5-HT1A receptor partial agonist [0.03%]
Huan Gao,Shen Wang,Qi Liu et al.
Huan Gao et al.
Depression has become a significant public health issue, highlighting the need for novel antidepressants. Based on the monoaminergic mechanisms of classical antidepressant drugs and the therapeutic potential of 5-HT1A receptor activation, w...
Paraprobiotics attenuate oxidative stress, dopaminergic neuron loss, and gut microbiome imbalance in an intranasal MPTP rat model of Parkinson's disease [0.03%]
Jacqueline Gomes,Eduarda Severo Rodrigues,Patrícia Santos Carvalhinho-Lopes et al.
Jacqueline Gomes et al.
Intestinal dysbiosis may contribute to the progression of Parkinson's disease (PD) by promoting inflammation and oxidative stress. Paraprobiotics, defined as non-viable microbial cells, have emerged as a promising therapeutic strategy. This...
Corrigendum to "Role of PPAR-β/δ/miR-17/TXNIP pathway in neuronal apoptosis after neonatal hypoxic-ischemic injury in rats" [Neuropharmacology 140 (2018) 150-161] [0.03%]
Marcin Gamdzyk,Desislava Met Doycheva,Jay Malaguit et al.
Marcin Gamdzyk et al.
Published Erratum
Neuropharmacology. 2026 May 7:111008. DOI:10.1016/j.neuropharm.2026.111008 2026
Olfactory bulb circuits drive ketamine-enhanced high-frequency oscillations via kainate and GABAergic mechanisms [0.03%]
Taisiia Prosvirova,Wiktoria Podolecka,Jacek Wrobel et al.
Taisiia Prosvirova et al.
Ketamine produces rapid antidepressant effects accompanied by marked changes in fast brain rhythms. High-frequency oscillations (HFO; 130-180 Hz) are an increasingly recognized signature of ketamine across species. However, their relationsh...
Corrigendum to "Omega-3-Enriched Fish oil reduces the chemotherapy-induced peripheral neuropathy in mice" [Neuropharmacology (2025) 271 110384 doi: 10.1016/j.neuropharm.2025.110384] [0.03%]
关于“富含欧米伽-3的鱼油可减少小鼠化疗诱导的外周神经病变”一文的勘误(神经药理学doi: 10.1016/j.neuropharm.2025.110384)
Jessica Melato,Fernanda Capitanio Goldoni,Larissa Benvenutti et al.
Jessica Melato et al.
Published Erratum
Neuropharmacology. 2026 May 6:110989. DOI:10.1016/j.neuropharm.2026.110989 2026
PPAR-α activation in a model of autism modulates social reward and endocannabinoid signaling selectively in male rats [0.03%]
激活PPAR-α可调节自闭症模型小鼠的社会奖赏行为和内源大麻素信号通路（仅在雄性小鼠中）
S Salviati,G Braccagni,E Corridori et al.
S Salviati et al.
Social difficulties in autism spectrum disorder (ASD), including reduced sensitivity and responsiveness to the rewarding value of social stimuli (social anhedonia), may arise from dysregulation of dopaminergic and endocannabinoid (eCB) path...
"Sex-Dependent Effects of Vasopressin Microinjections in CA3 on nucleus accumbens neurochemical modulation and Amphetamine-Induced Behavior" [0.03%]
血管加压素对海马CA3区性别依赖的作用及其对纹状体神经化学和苯丙胺诱导的行为的影响
Daniela Cáceres-Vergara,Tamara Bahamonde,Macarena F Gárate-Pérez et al.
Daniela Cáceres-Vergara et al.
Addiction to psychostimulants, such as amphetamine (AMPH), disrupts mesolimbic dopaminergic circuits, and effective pharmacological treatments remain limited. AMPH enhances dopamine (DA) release in the nucleus accumbens (NAc), a process tig...
BBB permeable selective HDAC3 inhibitor SP108 restores hippocampal plasticity and learning in a MAM-induced model of schizophrenia [0.03%]
新型表观遗传调节剂SP108改善小鼠精神分裂症样记忆和突触可塑性缺陷
Aparajita Ghosh,Himaja Ambati,Sanjeev Regula et al.
Aparajita Ghosh et al.
Schizophrenia is a complex neurodevelopmental disorder with cognitive impairment being one of the core features that remains largely unresponsive to current antipsychotic treatments. Histone deacetylase 3 (HDAC3), a negative regulator of me...