Trichothecosides A-D, antifungal sesquiterpene mannopyranosides from potato-associated fungus Trichothecium crotocinigenum [0.03%]
Ao-Ran Xu,Qiong Chen,Shan-Shan Huang et al.
Ao-Ran Xu et al.
Four previously unreported sesquiterpene glycosides, namely trichothecosides A-D (1-4), and one known compound (5) have been isolated from potato-associated fungus Trichothecium crotocinigenum. The structures were characterized through spec...
Integrated whole transcriptome sequencing, network pharmacology and in vivo validation reveal that Compound Wufengcao Liquid promotes pressure injury healing via PPARγ-mediated macrophage polarization [0.03%]
Rui Deng,Jiayan Qian,Qianqian Bu et al.
Rui Deng et al.
Compound Wufengcao Liquid (CoWFC) is a traditional herbal formulation that is widely acknowledged for its effectiveness in facilitating the healing of chronic wounds, particularly pressure injuries (PI). Despite its recognized efficacy, the...
Phenylpropanoids from the leaves and twigs of Croton mangelong and their biological activities [0.03%]
Yuan-Biao He,Jun-Nan Li,Qiu-Ye Xu et al.
Yuan-Biao He et al.
Three previously undescribed phenylpropanoids, (7R)-crotomanin O (1a), (7S)-crotomanin O (1b), and crotomanin P (2), along with five known compounds (3a, 3b, 4-6) were isolated from the leaves and twigs of Croton mangelong. Compounds 1a and...
An Jin,Gang Li,Nanxuan Shi et al.
An Jin et al.
Phytochemical investigation of the stems of Kadsura coccinea led to the isolation of seven previously undescribed dibenzocyclooctadiene lignans, designated kadcoccinlignans A-G (1-7), together with eight known analogues (8-15). The structur...
Coumarin derivatives in fibrosis therapy: Mechanistic insights from natural to synthetic scaffolds [0.03%]
Suraj Gupta,Ahil Sajeli Begum
Suraj Gupta
Fibrosis is characterized by the excessive deposition of extracellular matrix in various chronic conditions affecting the kidney, liver, heart, lungs, and other organs. Although research on the discovery of anti-fibrotic agents has been con...
Shuai-Long Yang,Li-Ting Pang,Hong-Fei Li et al.
Shuai-Long Yang et al.
Phytochemical investigation of the stems and leaves of the plant Melodinus tenuicaudatus led to the isolation of four previously unreported monoterpene indole alkaloid dimers, namely melocaudusines A-D (1-4), together with four known analog...
Diverse thymol analogs from Eupatorium fortunei: Their anti-inflammatory activity and mechanism [0.03%]
Rui Dong,Sheng-Li Wu,Xu Zhu et al.
Rui Dong et al.
Twenty-five thymol analogs including six new ones (1-6), along with a new phenylpropanoid (7), were isolated from Eupatorium fortunei Turcz. The structures of the new compounds were elucidated through comprehensive spectroscopic data analys...
Enhancement of plant resistance by naphthalene and polyketide derivatives from the coffee (Coffea arabica L.) endophyte Daldinia sp. BCFY-16 [0.03%]
Hua Xu,Wen-Zhi Shi,Wei Chen et al.
Hua Xu et al.
Three new naphthalene derivatives (1, 2, and 6), three new benzopyran-naphthalene hybrids (10-12), one new indanone (14), and two new polyketides (15 and 16), along with nine known compounds were isolated from the endophyte Daldinia sp. BCF...
Diarylheptanoid derivatives with α-synuclein aggregation inhibitory activities from the rhizome of Alpinia officinarum [0.03%]
Xue-Yi Li,Jun-Feng She,Qiu-Mei Lv et al.
Xue-Yi Li et al.
Seven undescribed diarylheptanoid derivatives, alpinins A - G (1-7), together with nine known ones (8-16), were isolated and identified from the rhizomes of Alpinia officinarum Hance. Architecturally, compounds 1-4 represent four unusual di...
Wen-Lan Meng,Yu Zhou,Fei-Fei Xiong et al.
Wen-Lan Meng et al.
The first phytochemical investigation on the aerial parts of Hypericum maclarenii resulting in the characterization of seven new polycyclic polyprenylated acylphloroglucinols (PPAP), hypermacones A - G (1-7), together with nine known analog...