Single cell transcriptomics in neuroscience: cell classification and beyond [0.03%]
单细胞转录组学在神经科学中的应用：细胞分类及其他方面研究
Bosiljka Tasic
Bosiljka Tasic
Biology has been facing a daunting problem since the cell was understood to be the building block of metazoans: how do we study multicellular systems, when a universal approach to characterize their building blocks and classify them does no...
Neural data science: accelerating the experiment-analysis-theory cycle in large-scale neuroscience [0.03%]
神经数据科学：加速大规模神经科学研究中的实验-分析-理论循环
L Paninski,J P Cunningham
L Paninski
Modern large-scale multineuronal recording methodologies, including multielectrode arrays, calcium imaging, and optogenetic techniques, produce single-neuron resolution data of a magnitude and precision that were the realm of science fictio...
Phillip Bokiniec,Niccolò Zampieri,Gary R Lewin et al.
Phillip Bokiniec et al.
Thermal information about skin surface temperature is a key sense for the perception of object identity and valence. The identification of ion channels involved in the transduction of thermal changes has provided a genetic access point to t...
Tobias Rose,Tobias Bonhoeffer
Tobias Rose
Experience-dependent plasticity in the visual system is traditionally thought to be exclusively cortical whereas the dorsal lateral geniculate nucleus (dLGN) is classically considered to just be a 'relay' of visual information between the r...
Origin and circuitry of spinal locomotor interneurons generating different speeds [0.03%]
起源和回路：脊髓运动中间神经元产生不同的速度
Henrik Boije,Klas Kullander
Henrik Boije
The spinal circuitry governing the undulatory movements of swimming vertebrates consist of excitatory and commissural inhibitory interneurons and motor neurons. This locomotor network generates the rhythmic output, coordinate left/right alt...
The hippocampus in depth: a sublayer-specific perspective of entorhinal-hippocampal function [0.03%]
海马深处：关于内侧颞叶皮层-海马环路亚层特异性的思考
Manuel Valero,Liset Menendez de la Prida
Manuel Valero
Understanding how the brain represents events is a fundamental question in neuroscience. The entorhinal-hippocampal system is central to such representations, which are severely compromised in some neurological diseases. In spite of much pr...
Action and learning shape the activity of neuronal circuits in the visual cortex [0.03%]
行为与学习塑造视觉皮层神经环路的活动
Janelle Mp Pakan,Valerio Francioni,Nathalie L Rochefort
Janelle Mp Pakan
Nonsensory variables strongly influence neuronal activity in the adult mouse primary visual cortex. Neuronal responses to visual stimuli are modulated by behavioural state, such as arousal and motor activity, and are shaped by experience. T...
What a predator can teach us about visual processing: a lesson from the archerfish [0.03%]
捕食者教会我们的视觉处理知识——以射水鱼为例
Mor Ben-Tov,Ohad Ben-Shahar,Ronen Segev
Mor Ben-Tov
The archerfish is a predator with highly unusual visually guided behavior. It is most famous for its ability to hunt by shooting water jets at static or dynamic insect prey, up to two meters above the water's surface. In the lab, the archer...
Matthew T Colonnese,Marnie A Phillips
Matthew T Colonnese
Thalamocortical activity patterns, both spontaneous and evoked, undergo a dramatic shift in preparation for the onset of rich sensory experience (e.g. birth in humans; eye-opening in rodents). This change is the result of a switch from thal...
Neural encoding of sensory and behavioral complexity in the auditory cortex [0.03%]
听觉皮层中感觉和行为复杂性的神经编码
Kishore Kuchibhotla,Brice Bathellier
Kishore Kuchibhotla
Converging evidence now supports the idea that auditory cortex is an important step for the emergence of auditory percepts. Recent studies have extended the list of complex, nonlinear sound features coded by cortical neurons. Moreover, we a...