Sex differences in the effects of adolescent intermittent ethanol exposure on exploratory and anxiety-like behavior in adult rats [0.03%]
青少年期间歇性乙醇暴露对成年大鼠探索和类焦虑行为的性别差异影响
Kati L Healey,Sandra A Kibble,Amelia Bell et al.
Kati L Healey et al.
Adolescent intermittent ethanol (AIE) exposure in rodents has been shown to alter adult behavior in several domains, including learning and memory, social interaction, affective behavior, and ethanol self-administration. AIE has also been s...
Structural, functional, and behavioral significance of sex and gonadal hormones in the basolateral amygdala: A review of preclinical literature [0.03%]
基底外侧杏仁核中性激素的结构、功能和行为意义：对临床前文献的回顾
Michaela E Price,Brian A McCool
Michaela E Price
The basolateral amygdala (BLA) is intimately involved in the development of neuropsychiatric disorders such as anxiety and alcohol use disorder (AUD). These disorders have clear sex biases, with women more likely to develop an anxiety disor...
Operant, oral alcohol self-administration: Sex differences in Sardinian alcohol-preferring rats [0.03%]
操作性条件作用下口服酒精自取用：撒丁岛喜酒大鼠中的性别差异
Irene Lorrai,Andrea Contini,Gian Luigi Gessa et al.
Irene Lorrai et al.
Sardinian alcohol-preferring (sP) rats have been selectively bred, over almost 40 years, for high alcohol preference and consumption. sP rats have served as an animal model for more than 120 published studies. With very few exceptions, howe...
Sexually divergent changes in select brain proteins and neurosteroid levels after a history of ethanol drinking and intermittent PTSD-like stress exposure in adult C57BL/6J mice [0.03%]
成年C57BL/6J小鼠饮酒和间歇性创伤后应激障碍后的脑蛋白及神经甾体性别差异变化研究
Leslie L Devaud,Mehrdad Alavi,Jeremiah P Jensen et al.
Leslie L Devaud et al.
Human studies reported that the number of past-year stressors was positively related to current drinking patterns, including binge drinking. In animal models, exposure to predator odor stress (PS), considered a model of traumatic stress, co...
CRF modulation of central monoaminergic function: Implications for sex differences in alcohol drinking and anxiety [0.03%]
CRF调节中枢单胺能功能：对酒精饮用和焦虑的性别差异的影响
Kristen E Pleil,Mary Jane Skelly
Kristen E Pleil
Decades of research have described the importance of corticotropin-releasing factor (CRF) signaling in alcohol addiction, as well as in commonly co-expressed neuropsychiatric diseases, including anxiety and mood disorders. However, CRF sign...
Sex differences in the synergistic effect of prior binge drinking and traumatic stress on subsequent ethanol intake and neurochemical responses in adult C57BL/6J mice [0.03%]
成年C57BL/6J小鼠一次性大量饮酒和应激的协同效应的性别差异对后续乙醇摄入及神经化学反应的影响
Deborah A Finn,Melinda L Helms,Michelle A Nipper et al.
Deborah A Finn et al.
Alcohol-use disorders (AUDs) are characterized by repeated episodes of binge drinking. Based on reports that exposure to predator odor stress (PS) consistently increases ethanol intake, the present studies examined whether prior binge drink...
Nicholas J Jury,Jeffrey F DiBerto,Thomas L Kash et al.
Nicholas J Jury et al.
Rates of alcohol use disorders (AUDs) differ between men and women, and there is also marked variation between sexes in the effects of acute and chronic alcohol. In parallel to observations in humans, prior studies in rodents have described...
Gender differences in ethanol-induced behavioral sensitivity in zebrafish [0.03%]
斑马鱼乙醇诱导的行为敏感性差异中的性别差异
Cynthia A Dlugos,Shereene J Brown,Richard A Rabin
Cynthia A Dlugos
Gender-related differential sensitivity to ethanol has long been recognized. Our previous studies have demonstrated that the zebrafish, an animal model used currently to study genetics and development related to a variety of human diseases,...
Comparative Study
Alcohol (Fayetteville, N.Y.). 2011 Feb;45(1):11-8. DOI:10.1016/j.alcohol.2010.08.018 2011
Elevated testosterone in females reveals a robust sex difference in altered androgen levels during chronic alcohol withdrawal [0.03%]
女性体内睾酮水平升高揭示了慢性酒精戒断期间雄激素水平变化的显著性别差异
Melissa R Forquer,Joel G Hashimoto,Melissa L Roberts et al.
Melissa R Forquer et al.
The endocrine disruption associated with alcohol (ethanol) abuse in both males and females is widely recognized. Ethanol intoxication and withdrawal in males results in significant reductions in androgen levels. Less is known about female a...
Alcohol consumption among patients with hepatitis B infection in northern Portugal considering gender and hepatitis B virus genotype differences [0.03%]
葡萄牙北部乙肝患者饮酒情况研究——不同性别和乙型肝炎病毒基因型间的差异分析
Ana Mota,Fátima Guedes,Jorge Areias et al.
Ana Mota et al.
Alcohol abuse is an important public health problem. In Portugal with a population of 10 millions of inhabitants, there are around 10% of alcoholics or excessive alcohol drinkers and 1% of chronically infected patients with hepatitis B viru...