Acute ethanol enhances septohippocampal coordination but disrupts intrinsic hippocampal theta dynamics during foraging [0.03%]
急性乙醇增强了觅食过程中的隔核-海马回路协调性但会破坏内源性海马θ节律动力学
Caleb B Darden,Meagan D Marks,Andrew J Kesner
Caleb B Darden
Theta oscillations - rhythmic patterns of synchronous activity within discrete brain regions - are known to support memory, navigation, and behavioral coordination, and are sensitive to pharmacological manipulation. Acute ethanol (EtOH) exp...
The Impact of Maternal Separation Stress on the CRFergic System in the Extended Amygdala and Its Relevance to Acute Stress-Induced Ethanol Consumption in Mice [0.03%]
母体分离压力对扩展杏仁核CRF能系统的影响及其与小鼠急性应激诱导的乙醇消费的相关性研究
Natalia Bonetti Bertagna,Cristiane Aparecida Favoretto,Ben Tagami Rodolpho et al.
Natalia Bonetti Bertagna et al.
Maternal separation (MS) is an early-life stressor associated with increased vulnerability to alcohol use disorders (AUD) later in life, potentially through alterations in corticotropin-releasing factor (CRF) signaling in the extended amygd...
Effects of Alcohol Use on the Gut, Inflammation, and Organ Injury: A Summary of the 2025 Alcohol and Immunology Research Interest Group (AIRIG) Meeting [0.03%]
酒精使用对肠道、炎症和器官损伤的影响：2025年酒精与免疫学研究兴趣小组（AIRIG）会议综述
Madison M Tschann,J Mark Brown,Summer L Thompson et al.
Madison M Tschann et al.
The 30th annual Alcohol and Immunology Research Interest Group (AIRIG) meeting was held on June 21st, 2025, at the Hyatt Regency in New Orleans, Louisiana as a satellite symposium of the Research Society on Alcohol (RSA) and International S...
Argument for the pharmacokinetically-informed preclinical researcher: A commentary for Alcohol [0.03%]
论药代动力学知识对临床前研究人员的重要性——兼论《酒精》期刊的一篇文章
Nicholas J Grahame
Nicholas J Grahame
The purpose of this commentary is to advocate for the importance of carefully considering ethanol pharmacokinetics when conducting preclinical studies involving alcohol consumption. Researchers working in this field commonly use alcohol dri...
Lateral hypothalamus CRFR1 regulation of binge drinking: divergence along anterior-posterior axis [0.03%]
下丘脑外侧CRFR1对醉酒的调节：沿前后轴分化
J L Ritchie,M R Eberle,J A Wojick et al.
J L Ritchie et al.
Ethanol induces neuroimmune dysregulation and soluble TREM2 generation in a human iPSC neuron, astrocyte, microglia triculture model [0.03%]
乙醇通过人类诱导多能干细胞神经元、星形胶质细胞和小胶质细胞共培养模型诱导神经免疫失调和可溶型TREM2产生
Andrew J Boreland,Yara Abbo,Xindi Li et al.
Andrew J Boreland et al.
Alcohol use disorders (AUDs) affect substantial populations worldwide and increase the risk of developing cognitive impairments and alcohol-associated dementia. While chronic inflammatory signaling likely plays an important role in alcohol-...
Low Level Alcohol Consumption is Associated with Lower Regional Brain Volume and Thickness and Lower Choline-Containing Compounds and Myo-Inositol Levels in Healthy Adults [0.03%]
低水平饮酒与健康成年人较低的大脑局部体积和厚度以及较低的胆碱类化合物和肌醇水平有关
Timothy C Durazzo,Brian D P Joseff,Dieter J Meyerhoff
Timothy C Durazzo
Low levels of alcohol consumption (e.g., up to two standard drink equivalents/day for males and one drink/day for females) have been viewed as benign or even beneficial, particularly for cardiovascular function. A limited number of studies ...
The impact of alcohol addiction on the quality of life, mental condition, clinical condition and nutritional status of patients with head and neck cancer [0.03%]
酒精成瘾对头颈部癌症患者生活质量、精神状态、临床状况和营养状况的影响
Karolina Dorobisz,Tadeusz Dorobisz,Katarzyna Pazdro-Zastawny et al.
Karolina Dorobisz et al.
Introduction: Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide, with over 880,000 new cases reported worldwide each year. Tobacco smoking and alcohol drinking are the main risk facto...
Ibudilast attenuates the association between pain intensity and heavy drinking in alcohol use disorder: A secondary analysis of a randomized clinical trial [0.03%]
イブディラスト用于酒精使用障碍的随机临床试验的事后分析：对酒精使用障碍患者镇痛作用的一项事后数据分析
Steven J Nieto,Erica N Grodin,Lara A Ray
Steven J Nieto
Background: Pain frequently co-occurs with alcohol use disorder (AUD) and may influence treatment response. In this secondary analysis of a completed randomized clinical trial, we examined whether baseline pain intensity ...
N-acetylcysteine prevents ethanol-induced neuropathic pain by downregulating nociceptive activation of supraspinal brain areas [0.03%]
N-乙酰半胱氨酸通过下调脊髓以上脑区的痛敏反应预防酒精诱导的神经病理性疼痛
Natália Gabriele Hösch,Raíssa A F Reis,Rômulo Dias Novaes et al.
Natália Gabriele Hösch et al.
Considering the important clinical applications of N-acetylcysteine (NAC), the present study investigated the effects of NAC treatment on ethanol-induced neuropathic alterations. For this purpose, a total number of eighty-one male adult Wis...