Trigonelline, a plant derived alkaloid prevents ultraviolet-B-induced oxidative DNA damage in primary human dermal fibroblasts and BALB/c mice via modulation of phosphoinositide 3-kinase-Akt-Nrf2 signalling axis [0.03%]
植物衍生的生物碱三角亚铃碱通过调控磷脂酰肌醇3激酶-Akt-Nrf2信号轴，预防紫外线引起的氧化DNA损伤在原代人皮肤成纤维细胞和BALB/c小鼠中发生
Malik A Tanveer,Haroon Rashid,Lone A Nazir et al.
Malik A Tanveer et al.
Background: DNA is the main target for UV-B-irradiation-induced skin photodamage and accounts for 90 % of all the non-melanoma skin cancers. Purpose: ...
The interaction between aging and protein malnutrition modulates peritoneal macrophage function: An experimental study in male mice [0.03%]
衰老与蛋白质营养不良之间的相互作用调节腹膜巨噬细胞的功能：雄性小鼠的实验研究
Gabriela Kodja Vivian,Renaira Oliveira da Silva,Andressa Cristina Antunes Santos et al.
Gabriela Kodja Vivian et al.
Malnutrition is considered one of the most common problems in the elderly population worldwide and can significantly interfere in health evolution in these individuals, predisposing them to increased infection susceptibility. The immune res...
Novel shaking exercises for hippocampal and medial prefrontal cortex functioning maintain spatial working memory [0.03%]
新型的摇晃运动可以维持空间工作记忆并活化海马和内侧前额皮质的功能
Runhong Yao,Kouji Yamada,Takumi Kito et al.
Runhong Yao et al.
Introduction: The decline in spatial working memory is one of the earliest signs of normal brain aging. Objective: We developed a novel...
Diğdem Lafcı,Mağfiret Kaşikçi
Diğdem Lafcı
Background: Constipation is a health problem commonly seen in the elderly individuals. Abdominal massage is thought to stimulate the rectal loading by increasing intra-abdominal pressure. ...
Randomized Controlled Trial
Experimental gerontology. 2023 Jan:171:112023. DOI:10.1016/j.exger.2022.112023 2023
Effects of age, sex, frailty and falls on cognitive and motor performance during dual-task walking in older adults [0.03%]
年龄、性别、脆弱状态和跌倒对老年人双任务行走中认知和运动表现的影响
Elodie Piche,Frédéric Chorin,Pauline Gerus et al.
Elodie Piche et al.
Background: Dual-task (DT) walking is of great interest in clinical evaluation to evaluate the risk of falling or cognitive declines in older adults. However, it appears necessary to investigate deeply the confounding fac...
SARC-F predicts poor motor function, quality of life, and prognosis in older patients with cardiovascular disease and cognitive impairment [0.03%]
SARC-F预测心血管疾病和认知障碍的老年患者运动功能、生活质量及预后不良
Takumi Noda,Kentaro Kamiya,Nobuaki Hamazaki et al.
Takumi Noda et al.
Objectives: We investigated whether SARC-F scores were associated with motor function, quality of life (QOL) related to physical function, and prognosis in older patients with cardiovascular disease (CVD) and cognitive im...
The tissue factor expression on CD14++CD16-monocytes is a new markers in the Chinese Han older adult population with sepsis: A prospective study [0.03%]
CD14++CD16-单核细胞上组织因子的表达是中国汉族脓毒症老年人群中的一种新标志物：一项前瞻性研究
Qian Gao,Li Yang,Fei Teng et al.
Qian Gao et al.
Objective: To investigate the tissue factor (TF) expression on different subsets of monocyte and tissue factor secretion of peripheral blood and evaluate their association with the prognosis of sepsis in the Chinese older...
Early cardiac aging linked to impaired stress-resistance and transcriptional control of stress response, quality control and mitochondrial pathways [0.03%]
早期心脏老化与压力抵抗能力下降及压力反应、质量控制和线粒体通路的转录控制障碍有关
Kevin J Ashton,Can J Kiessling,Jamie-Lee M Thompson et al.
Kevin J Ashton et al.
Phenotypic and transcriptomic evidence of early cardiac aging, and associated mechanisms, were investigated in young to middle-aged male mice (C57Bl/6; ages 8, 16, 32, 48 wks). Left ventricular gene expression (profiled via Illumina MouseWG...
Longitudinal association between grip strength and the risk of heart diseases among European middle-aged and older adults [0.03%]
握力与欧洲中老年人心脏病风险的纵向联系研究
Miguel Peralta,Carlos Matias Dias,Adilson Marques et al.
Miguel Peralta et al.
Background: Few multi-country European studies have investigated the association between grip strength and heart diseases incidence. Thus, the aim of this study is to analyse the longitudinal relationship between grip str...
Inflammaging and body composition: New insights in diabetic and hypertensive elderly men [0.03%]
炎症老化与身体构成：糖尿病和高血压老年男性的新见解
Caroline Vieira Gonçalves,Israel Souza Ribeiro,Maria Poliana Leite Galantini et al.
Caroline Vieira Gonçalves et al.
Age-related changes in the body's physiological responses play a critical role in systemic arterial hypertension (SAH) and type 2 Diabetes mellitus (T2DM). SAH and T2DM have clinically silent low-grade inflammation as a common risk factor. ...