GDLAM and SPPB batteries for screening sarcopenia in community-dwelling Spanish older adults: Healthy-age network study [0.03%]
用于筛查居住在社区的西班牙老年人肌肉减少症的GDLAM和SPPB电池：健康年龄网络研究
Pablo Jorge Marcos-Pardo,Noelia González-Gálvez,Ana Carbonell-Baeza et al.
Pablo Jorge Marcos-Pardo et al.
Objectives: To determine the diagnostic ability of GDLAM and SPPB batteries to classify people with sarcopenia according to the European Working Group on Sarcopenia in Older People (EWGSOP19). ...
The effects of resveratrol and melatonin on biochemical and molecular parameters in diabetic old female rat hearts [0.03%]
白藜芦醇和褪黑素对老年雌性糖尿病大鼠心脏生化和分子参数的影响
Nilufer Akgun-Unal,Serhan Ozyildirim,Omer Unal et al.
Nilufer Akgun-Unal et al.
The roles of melatonin and resveratrol-enhanced activation of SIRT1 (silent information regulator 1), GLUT4 (glucose transporter type 4), and PGC-1α (peroxisome proliferator-activated receptor gamma coactivator 1-alpha) in mediating the pr...
Young plasma transfer recovers decreased sperm counts and restores epigenetics in aged testis [0.03%]
年轻血浆转移恢复了老年睾丸减少的精子数量并恢复了表观遗传学
Kadriye Erdogan,Taha Ceylani,Hikmet Taner Teker et al.
Kadriye Erdogan et al.
Background and aim: Aging is one of the causes of male infertility, and abnormal global DNA methylation and imprinting defects have been characterized in testis during biological aging. One of the important emerging appro...
Low-intensity resistance training to improve knee extension strength in community-dwelling older adults: Systematic review and meta-analysis of randomized controlled studies [0.03%]
低强度抗阻训练提高社区居住老年人膝关节伸肌力量的系统评价和随机对照研究的荟萃分析
Midori Kamiya,Hikaru Ihira,Yoshiaki Taniguchi et al.
Midori Kamiya et al.
Aim: The purpose of this systematic review and meta-analysis was to investigate the effects of low-intensity resistance training on knee extension strength with respect to intensity, frequency, duration and training site ...
Translational research into frailty from bench to bedside: Salivary biomarkers for inflammaging [0.03%]
脆弱性从实验台到病床的转化研究：唾液生物标志物用于炎症老龄化研究
Alfonssina Niebla-Cárdenas,Halin Bareke,Pablo Juanes-Velasco et al.
Alfonssina Niebla-Cárdenas et al.
Frailty is a complex physiological syndrome associated with adverse ageing and decreased physiological reserves. Frailty leads to cognitive and physical disability and is a significant cause of morbidity, mortality and economic costs. The u...
The effect of high intensity interval training with genistein supplementation on mitochondrial function in the heart tissue of elderly rats [0.03%]
高强度间歇训练联合大豆异黄酮补充对老年大鼠心肌线粒体功能的影响
Rostam Alizadeh,Omidreza Salehi,Najmeh Rezaeinezhad et al.
Rostam Alizadeh et al.
Introduction: For the most part, heart disease increases with age; on the other hand, although the role of exercise and antioxidants in the health of the elderly has been reported, the simultaneous effect of these two int...
Strength versus endurance trained master athletes: Contrasting neurophysiological adaptations [0.03%]
力量型与耐力型大师级运动员的对比神经生理适应性变化
Tiril Tøien,Runar Unhjem,Ole Kristian Berg et al.
Tiril Tøien et al.
Neural factors play a critical role in the age-related decline in maximal strength and rate of force development (RFD). However, it is uncertain how the age-related attenuation in neuromuscular function may be mitigated in strength or endur...
Age, hemodialysis time, gait speed, but not mortality, are associated with muscle quality index in end-stage renal disease [0.03%]
年龄、血液透析时间、步速但并非死亡率与终末期肾病的肌肉质量指数相关
Jessica F Mayrink Ivo,Clara S A Sugizaki,Ana Tereza V Souza Freitas et al.
Jessica F Mayrink Ivo et al.
Background: The muscle quality index (MQI) has proven to be an interesting clinical measurement in hemodialysis (HD) patients. In clinical practice, its interpretation can be biased by fat mass (FM) distribution. This stu...
Mesencephalic astrocyte-derived neurotrophic factor (MANF) prevents the neuroinflammation induced dopaminergic neurodegeneration [0.03%]
中脑星形胶质细胞源性神经营养因子（MANF）预防神经炎症诱导的多巴胺能神经变性
Jing-Xing Zhang,Kai-Ge Zhou,Yan-Xin Yin et al.
Jing-Xing Zhang et al.
Background: The excessive activation of the microglia leads to the release of inflammatory factors that contribute to neuronal cell loss and neurodegeneration in Parkinson's Disease (PD). Mesencephalic astrocyte-derived n...
Effects of APOEɛ4 genotype on age-associated change in cognitive functions among Japanese middle-aged and older adults: A 20-year follow-up study [0.03%]
APOEɛ4基因型对日本中老年人年龄相关认知功能变化的影响：一项历时20年的随访研究
Yukiko Nishita,Giovanni Sala,Mitsuru Shinohara et al.
Yukiko Nishita et al.
Background and aims: Carriers of the apolipoprotein E ε4 allele (APOEɛ4) have an increased risk of developing dementia (e.g., Alzheimer's disease). However, it is less clear whether the APOEɛ4 might also be involved in...