Iron dysregulation and mitochondrial dysfunction in aging: A longitudinal study on mobility decline in low- and high-functioning older adults [0.03%]
铁代谢紊乱和线粒体功能障碍与老年人行动能力下降的关系：一项关于低活动能力和高活动能力老年人的纵向研究
Nevena Stanojevic,Stephanie Wohlgemuth,Rola S Zeidan et al.
Nevena Stanojevic et al.
Background: Mobility loss in older adults reduces quality of life and increases risks of falls, hospitalizations, and mortality. Low-functioning (LF) older adults experience faster mobility decline than their high-functio...
Comparative effects of EXG and conventional therapies on muscle strength and balance in older people: A meta-analysis and meta-regression [0.03%]
EXG和传统疗法对老年人肌肉力量和平衡的比较效果的meta分析和meta回归分析
Jordan Hernandez-Martinez,Edgar Vasquez-Carrasco,Izham Cid-Calfucura et al.
Jordan Hernandez-Martinez et al.
This systematic review with meta-analysis aimed to analyze the effects of exergaming (EXG) versus conventional therapies on muscle strength, balance, and fear of falling in healthy older people. A systematic literature search was conducted ...
Associations of frailty, oral health, and dietary well-being with risk of malnutrition among rural community-dwelling older adults: A cross-sectional study [0.03%]
脆弱性、口腔健康和饮食状况与农村社区老年人营养不良风险的关系：一项横断面研究
Ya-Wen Kuo,Hsiu-Fan Hsu,Wen-Li Hou et al.
Ya-Wen Kuo et al.
Background: The risk of malnutrition is common among older adults and is influenced by factors such as frailty, oral health, and dietary well-being. This study examined the association of frailty, masticatory performance,...
Cumulative diabetes-related metabolic burden and the risk of hearing loss: A population-based study [0.03%]
累积的糖尿病相关代谢负担与听力损失风险的流行病学研究
Youngji Han,Kyu-Yup Lee,Incheol Seo et al.
Youngji Han et al.
Type 2 diabetes mellitus (T2DM) causes microvascular injury across multiple organs, but whether its cumulative microvascular burden contributes to sensory decline remains unclear. In this population-based cohort of 493,272 UK Biobank partic...
Exploring the causal relationship between osteoporosis and age-related macular degeneration: Evidence from observational studies and mendelian randomization [0.03%]
基于观察性研究和孟德尔随机化的证据探究骨质疏松与年龄相关性黄斑变化之间的因果关系
Huan Liu,Xiaoping Sun,Jiang Liu et al.
Huan Liu et al.
Objective: This study aimed to systematically investigate the association between osteoporosis (OP) and age-related macular degeneration (AMD), including its subtypes, by integrating observational evidence with causal inf...
From treadmill to outdoor overground walking: Enhancing ground contact timing detection for older adults using transfer learning [0.03%]
从跑步机到户外行走：使用迁移学习增强老年人足底接触时机检测能力
Sailee Sansgiri,Emmi Matikainen-Tervola,Merja Rantakokko et al.
Sailee Sansgiri et al.
Identification of ground contact timings (GCT) is critical for monitoring mobility in older adults. Laboratory methods are precise but limited to controlled environments, restricting their applicability in real-world settings. Treadmills al...
On exploring muscle aging of the biceps brachii in the middle-aged population using HD-sEMG signal analysis [0.03%]
基于HD-sEMG信号分析的中年人群肱二头肌肌肉衰老特征探索研究
Kawtar Ghiatt,Ahmad Diab,Chawki Nasrallah et al.
Kawtar Ghiatt et al.
Although neuromuscular decline is well documented with aging, emerging evidence indicates that it may begin as early as midlife, around age 50. As this stage represents a critical window for early intervention, the present study investigate...
Correlation between sarcopenia and changes in oligodendrocyte lineage cells in the brains of Alzheimer's disease model mice [0.03%]
阿尔茨海默病模型小鼠骨骼肌减少与脑内少突胶质细胞谱系变化之间的关联
Lin-Lin Yao,Xiao-Ting Ma,Fang-Bo Li et al.
Lin-Lin Yao et al.
Background: Alzheimer's disease (AD) is a neurodegenerative disorder primarily characterized by cognitive dysfunction. The discovery and identification of non-cognitive symptoms in the preclinical stage hold promise for e...
Changjun Li,Heather Allore,Michael O Harhay et al.
Changjun Li et al.
Detecting heterogeneity in treatment response enriches the interpretation of gerontologic trials. In aging research, estimating the intervention's effect on clinically meaningful outcomes poses analytical challenges when outcomes are trunca...
Disulfidptosis in osteoarthritis: Role of SLC2A3 downregulation and potential therapeutic implications [0.03%]
骨关节炎中的二硫化物积聚：SLC2A3下调的作用及潜在治疗意义
Ruoyang Feng,Xiadiye Tuerhong,Yongsong Cai et al.
Ruoyang Feng et al.
Objective: Disulfidptosis is a newly recognized form of regulated cell death characterized by actin cytoskeleton collapse under disulfide stress. Recent studies suggest it may significantly contribute to osteoarthritis (O...