Katarina Pus,Fabio Sarto,Marco Narici et al.
Katarina Pus et al.
Background: Aging leads to progressive motor system decline, which can result in sarcopenia, defined as the age-related loss of muscle mass and function. Architectural changes, epitomized by a decrease in fascicle length ...
Metabolomic biomarkers enhance 10-year mortality risk calibration and clinical utility in older heart failure patients: A UK Biobank study [0.03%]
Xiaofeng Zeng,Shuli Jia,Wenwu Cheng et al.
Xiaofeng Zeng et al.
Background and aims: While current heart failure models focus on short-term outcomes, long-term risk prediction is essential for an aging population. Given that heart failure is often the terminal manifestation of systemi...
Association of Dietary Inflammatory Index (DII) with cardiovascular and all-cause mortality in patients with Cardiovascular-Kidney-Metabolic (CKM) syndrome: a prospective cohort study [0.03%]
Rui Sun,Xintong Li,Xinhai Cui et al.
Rui Sun et al.
Background: Cardiovascular-kidney-metabolic syndrome (CKM) is closely associated with obesity, diabetes, chronic kidney disease (CKD), and cardiovascular disease (CVD). Although the dietary inflammatory index (DII) reflec...
Exploring the causal link between long-term elevated plasma caffeine levels and age-related eye diseases using Mendelian randomization [0.03%]
Hao Dong,Qiang Ding,Mei Liu
Hao Dong
Objective: Experimental evidence suggests that caffeine has the potential to reduce the risk of age-related eye diseases (AREDs). However, there is a lack of population-based evidence directly assessing whether long-term ...
High-speed vs. low-speed resistance training on muscle function in individuals with low muscle mass and obesity [0.03%]
低肌量和肥胖个体的高速与低速阻力训练对肌肉功能的影响
Kuo-Jen Hsu,Yu-Wei Ching,Hsi-Min Hsiung et al.
Kuo-Jen Hsu et al.
Purpose: This study investigated the effects of high-speed (HSRT) and low-speed resistance training (LSRT) on muscle function in individuals with low muscle mass and obesity (LMO). ...
Association between enteral nutrition formula types and initial time with prognosis in moderately severe and severe acute pancreatitis: A 5-year retrospective multi-center study [0.03%]
不同肠内营养制剂与中重度急性胰腺炎早期阶段预后的相关性研究：一项五年回顾性多中心研究
Tongtian Ni,Dayi Zhang,Tenzing Dava et al.
Tongtian Ni et al.
Objectives: Moderately severe or severe acute pancreatitis (MSAP/SAP) is a crucial abdominal disorder. Enteral nutrition (EN) is a central issue after patients pass through the resuscitation stage. The preference for EN f...
Metabolic flexibility following resistance exercise and a high protein diet in older men: results from a 12-week randomized controlled trial [0.03%]
一项针对老年男性进行的12周随机对照试验结果：抵抗运动和高蛋白饮食后的代谢灵活性
Corbin Griffen,Derek Renshaw,Michael Duncan et al.
Corbin Griffen et al.
Purpose: Aging and sarcopenia are associated with metabolic inflexibility. This study investigated the effects of resistance exercise (RE) and a high protein diet (PRO) on metabolic flexibility (the ability to adjust rate...
Mammalian target of rapamycin in chronic liver disease and the potential for therapeutic manipulation [0.03%]
雷帕霉素哺乳动物靶点在慢性肝病中的作用及治疗干预的可能性
Pramudi Wijayasiri,Mamatha Bhat,Aloysious D Aravinthan
Pramudi Wijayasiri
Chronic Liver Disease (CLD) represents a growing epidemic in the Western world, yet treatment options that effectively slow its progression remain limited. Mammalian target of rapamycin (mTOR) inhibitors, such as sirolimus (also known as ra...
Mediterranean diet preserves renal mitochondrial homeostasis and attenuates early diabetic kidney injury in db/db mice [0.03%]
地中海饮食可保持肾脏线粒体稳态并减轻db/db小鼠早期糖尿病肾损伤
Giovanna Mercurio,Antonia Giacco,Nicla Scopigno et al.
Giovanna Mercurio et al.
Background: Chronic hyperglycemia, oxidative stress, and mitochondrial dysfunction are central drivers of renal structural and functional alterations associated with metabolic disease and accelerated tissue aging. In type...
Joint effects of cardiometabolic index and remnant cholesterol on cardiovascular disease in cardiovascular-kidney-metabolic syndrome stages 0-3: a nationwide cohort study [0.03%]
心血管肾脏代谢综合征0-3期人群循环代谢指标与残余胆固醇的联合效应：全国范围队列研究
Xiaojing Zhou,Yu Liang,Juan Zhang et al.
Xiaojing Zhou et al.
Background: The cardiometabolic index (CMI) and remnant cholesterol (RC) reflect different aspects of adiposity and triglyceride-rich lipoprotein metabolism in cardiovascular-kidney-metabolic (CKM) syndrome. Whether their...