Qiliqiangxin capsule improves the cognitive disorders in heart failure rats through regulating blood brain barrier function [0.03%]
奇苈强心胶囊通过调节血脑屏障功能改善心力衰竭大鼠认知障碍
Hongbing Zhao,Yue Zhao,Jinfang Dou et al.
Hongbing Zhao et al.
Objective: This study aimed to investigate the protective effects of Qiliqiangxin capsule (QLQX) against cognitive impairment in rats with heart failure (HF), as well as the underlying mechanisms. ...
The correlation between changes in intrinsic capacity of older adults in Chinese communities and adverse health-related outcomes: A prospective longitudinal Cohort study [0.03%]
我国社区老年人内在能力变化与不良健康结果的关联性分析：一项前瞻性队列研究
Yaru Zhou,Wenhua Yu,XiaoHong Liu
Yaru Zhou
Backgrounds: Preserving intrinsic capacity (IC) is essential for healthy aging. This study examined the associations between longitudinal changes in IC and subsequent adverse health outcomes. ...
Accelerated intermittent theta burst stimulation combined with cognitive training modulates cortical plasticity and brain activation in patients with amnestic mild cognitive impairment [0.03%]
加速间歇θ节律爆发刺激联合认知训练调节遗忘型轻度认知障碍患者皮质可塑性及脑激活
Jiali Luo,Zefeng Tan,Pan Shang et al.
Jiali Luo et al.
Amnestic mild cognitive impairment (aMCI) is the prodromal period of Alzheimer's disease without effective treatment. This research aimed to investigate the effects of accelerated intermittent theta burst stimulation (iTBS) combined with ad...
Optimizing recovery after a hip fracture: Protocol of a randomized controlled trial to study the effects, costs, and cost-effectiveness of a combined protein and exercise intervention in older adults after a hip fracture (ProBUS study) [0.03%]
股骨骨折后的优化恢复：老年股骨骨折患者蛋白质和锻炼联合干预效果、成本及效益的随机对照试验方案（ProBUS研究）
Emma Treijtel,Hugo H Wijnen,Nienke M S Golüke et al.
Emma Treijtel et al.
Background: Hip fractures are common among older adults and typically occur alongside accumulating comorbidities and age-related musculoskeletal decline. While nutritional or exercise interventions can support recovery, t...
Disentangling the overlap between frailty and intrinsic capacity in older adults [0.03%]
梳理老年人虚弱和内在能力之间的重叠关系
Yuwei Qi,Natasja M van Schoor,Laura A Schaap et al.
Yuwei Qi et al.
Introduction: It has been suggested that two prominent frameworks in geriatrics, frailty and intrinsic capacity (IC), represent two opposite ends of the same continuum. Frailty quantifies accumulated deficits and vulnerab...
Persistent musculoskeletal pain and subsequent falls in China: Evidence from CHARLS with exploratory frailty mediation analyses [0.03%]
中国社区老年人慢性疼痛与跌倒的纵向关系及其潜在机制：CHARLS数据探索性分析
Ruizheng Zhu,Guangjun Tang,Manhong Yang et al.
Ruizheng Zhu et al.
Background: Musculoskeletal pain (MSP) is prevalent among middle-aged and older adults and may increase fall risk through functional decline, but evidence on pain persistence and the potential role of frailty in China rem...
Association between C-reactive protein-triglyceride glucose index and risk of sarcopenia in older adults: findings from CHARLS and NHANES [0.03%]
基于CHARLS和NHANES研究探讨CRP-TG-GLU指数与老年人肌少症风险的关系
Yan Chen,Tianchong Huang,Jiayin Wang et al.
Yan Chen et al.
Background: Insulin resistance (IR) and inflammation are two crucial risk factors of sarcopenia. C-reactive protein-triglyceride glucose index (CTI) has been proposed to be a novel biomarker reflecting IR and inflammation...
Chronotype, serum metabolome, and nonalcoholic fatty liver disease in middle-aged and older adults: Association and potential mediation analyses [0.03%]
昼夜节律、血清代谢组与中老年人非酒精性脂肪肝病的关联及潜在中介作用分析
Ming-Jun Hu,Xiao-Min Dong,Xue-Li Wang et al.
Ming-Jun Hu et al.
Objective: Chronotype represents individual's circadian preference in behavioral and circadian rhythm. This study aimed to investigate association between chronotype and nonalcoholic fatty liver disease (NAFLD) and underl...
Immune cell-associated DNA methylation responses to exercise in women: A bioinformatics analysis comparing pre- and postmenopausal stages [0.03%]
基于生物信息学的绝经前后妇女运动应答差异的免疫细胞相关DNA甲基化研究
Guilherme da Silva Rodrigues,Natalia Yumi Noronha,Andressa Crystine da Silva Sobrinho et al.
Guilherme da Silva Rodrigues et al.
Introduction: Menopause is associated with immunosenescence and altered immune profiles, potentially reducing immune competence. Physical exercise may counteract these changes by modulating DNA methylation in fitness-rela...
Distinct patterns of cortical activity associated with cognitive and motor decline in community-dwelling older adults [0.03%]
与社区老年人认知和运动功能衰退相关的皮层活动模式
Eun-Seon Noh,Jiwon Yang,Kai Wang et al.
Eun-Seon Noh et al.
This study aimed to examine whether resting-state EEG markers show potential for distinguishing individuals as healthy control, mild cognitive impairment (MCI), and motoric cognitive risk syndrome (MCR), based on their levels of cognitive a...