Interpretable machine learning for cognitive impairment screening: Development and external validation of a clinical prediction model based on NHANES data [0.03%]
基于NHANES数据的认知障碍筛查的可解释机器学习：临床预测模型的开发和外部验证
Kang Chen,Guran Yu,Hao Li
Kang Chen
Background: Cognitive impairment in older adults poses a growing public health challenge, yet accessible screening tools remain limited. We aimed to develop and validate an interpretable machine learning model for cogniti...
The skeletal muscle function deficit: From an operational definition to clinic results from the InCHIANTI longitudinal study [0.03%]
骨骼肌功能缺陷：从操作定义到InCHIANTI纵向研究的临床结果
Angelo Di Iorio,Raffaello Pellegrino,Roberto Paganelli et al.
Angelo Di Iorio et al.
Age-related muscle dysfunction is a major contributor to disability, frailty, and poor clinical outcomes in older adults. Skeletal Muscle Function Deficit (SMFD) framework integrates multiple domains as: muscle mass, muscle density, strengt...
Bidirectional associations between metabolic syndrome and epigenetic age acceleration: A 20-year longitudinal study in midlife adults [0.03%]
代谢综合征与表观遗传学衰老加速之间的双向关联：中年成年人20年的纵向研究
Hye-Young Park,Kyeezu Kim
Hye-Young Park
Introduction: Metabolic syndrome (MetS) increases with age. Epigenetic alterations reflect lifelong biological and environmental influences on aging. MetS may contribute to epigenetic age acceleration (EAA) through inflam...
Maryam Fallah,Fatemeh Naeini,Fatemeh Sadat Fahimzad et al.
Maryam Fallah et al.
Immunonutrition refers to nutritional interventions that can improve immune function. The nutritional contents used in immunocytes include amino acids, vitamins, minerals, and flavonoids. In this study, we examine the oxi-inflamm-aging theo...
Association of grip indicators with post-discharge recovery in geriatric and hip fracture inpatients [0.03%]
握力指标与老年患者和髋部骨折患者的术后恢复之间的关系
Myrthe Swart,Merle Geerds,Ivan Bautmans et al.
Myrthe Swart et al.
Objectives: Hand grip measures offer potential indicators for recovery after hospitalization in older adults. We investigated prospective associations of the grip indicators maximal grip strength (GSmax), fatigue resistan...
The impact of adapted tango dance on cognitive and executive function in older adults: A randomized controlled trial [0.03%]
一项随机对照试验：改编探戈舞对老年人认知功能和执行功能的影响
Yuexin Zhang,Hongli Zhang,Hongtao Ma
Yuexin Zhang
Purpose: This study aimed to evaluate the effects of a 12-week adapted tango program on executive and cognitive function in older adults. Methods: ...
Autonomous fall risk assessment in Australian Residential Aged Care Facilities using passive sensors: A feasibility study [0.03%]
基于被动传感器的澳大利亚养老机构居民跌倒风险自主评估研究
David Silvera-Tawil,Jane Li,Liesel Higgins et al.
David Silvera-Tawil et al.
Background: Falls in residential aged care home (RAC) remain a critical issue in Australia, contributing to diminished quality of life and increased morbidity among older adults. This study investigates the feasibility of...
Ginsenoside Rb1 attenuates arterial aging by reducing DNA damage in aged mice [0.03%]
红参皂苷Rb1通过减少DNA损伤来缓解老年小鼠的动脉衰老现象
Qi Si,Lin Wu,Ximei Zhang et al.
Qi Si et al.
Objective: Vascular aging is a critical risk factor for the development and progression of cardiovascular diseases. Age-related degenerative changes in vascular structure and function significantly promote the onset of va...
Therapeutic effects of Total flavonoids of Epimedium Folium on sarcopenia via modulation of gut microbiota and bile acid metabolism [0.03%]
Epimedium叶总黄酮通过调节肠道菌群和胆汁酸代谢改善少肌症的作用研究
Yujie Zhang,Zhe Pan,Jiewen Shi et al.
Yujie Zhang et al.
Background: The total flavonoids of Epimedii Folium (Epimedium brevicornu Maxim.) are the main active component, and have unique advantages in sarcopenia intervention. Nevertheless, its efficacy and mechanism of action ha...
Mediating role of neutrophil-percentage-to-albumin ratio in the association between stroke and heart failure among U.S. adults [0.03%]
中性粒细胞比率-白蛋白比值在卒中与心力衰竭关联中的介导作用
Yan Zhao,Tingting Chen,Conghua Ji et al.
Yan Zhao et al.
Background: Stroke is an independent risk factor for heart failure (HF), and they are both linked to systemic inflammation. The neutrophil-percentage-to-albumin ratio (NPAR) is a novel inflammation biomarker. However, it ...