An unrecognized hazard of inhaled 6:2 FTOH: Pulmonary transformation and interfacial toxicity in the lung [0.03%]
一种吸入性6:2 FTOH的未被认识到的危险：肺部转化及界面毒性
Linfeng Zhang,Yan Cao,Haoran Song et al.
Linfeng Zhang et al.
Evidence for the transformation of volatile fluorotelomer alcohols (FTOHs) after respiratory uptake remains elusive, and the role of their surface activity in health risk has been overlooked. Herein, the 6:2 FTOH interaction with the pulmon...
Photoaging amplified the inhibition of microplastics on salivary amylase function via affecting the structure of α-helix: From in vitro digestive models to human samples [0.03%]
光老化通过影响α-螺旋结构增强微塑料对唾液淀粉酶功能的抑制：从体外消化模型到人体样本研究
Han Li,Shusi Wang,Jing He et al.
Han Li et al.
Microplastics (MPs), as ubiquitous environmental contaminants, inevitably undergo photoaging processes. Critically, the predominant route of human exposure to environmental MPs is oral ingestion, thereby establishing the digestive system as...
Building transparency, credibility and trust in evidence synthesis practice: why editorial standards and policies matter [0.03%]
建立证据综合实践的透明性、可信性和信任：编辑标准和政策为何重要
Nicolas Roth,Yefeng Yang,Frederic Coulon et al.
Nicolas Roth et al.
Editorial standards are not administrative formalities; they function as scientific quality control mechanisms that directly shape the validity, credibility, integrity, and utility of published research. Since 2016, Environment Internationa...
Distinctive respiratory toxicity induced by hypoxanthine metabolic disorder from polystyrene microplastics and nanoplastics at environmentally relevant doses: multi-omics insights and experimental validation [0.03%]
环境相关剂量下聚苯乙烯微塑料和纳米塑料通过次黄嘌呤代谢紊乱诱导的特异性呼吸毒性：多组学见解与实验验证
Xiaole Xu,Mengnan He,Meiqi Lan et al.
Xiaole Xu et al.
Microplastics (MPs) and nanoplastics (NPs) are pervasive environmental contaminants, raising concerns about their potential to cause inflammation, oxidative stress, and lung injury through respiratory toxicity. Due to their smaller size, la...
Bisphenol-A from environment macro-circulation to human micro-circulation: a novel link to abdominal aortic aneurysm [0.03%]
从环境大循环到人体微循环的双酚A：与腹主动脉瘤的新联系
Shuli Zhang,Feilong Zhang,Dandan Liu et al.
Shuli Zhang et al.
The current fragmented nature of research impedes a comprehensive understanding of the mechanistic pathways linking environmental exposure to emerging pollutants and their pathogenic outcomes. This study establishes a systematic framework l...
Sensitive windows of per- and polyfluoroalkyl substances exposure and children's intelligence quotient [0.03%]
环境中多氟化合物暴露的敏感时期与儿童智商的关系研究
Yanan Xing,Hong Gan,Dihui Xu et al.
Yanan Xing et al.
Accurate identification of critical windows of neurodevelopmental susceptibility to per- and polyfluoroalkyl substances (PFAS) exposure across the prenatal-to-childhood continuum carries significant public health implications. Although PFAS...
Associations between maternal blood lead concentration during pregnancy and trajectories of wheezing and asthma in offspring: The Japan Environment and Children's Study (JECS) [0.03%]
孕期母亲血液铅浓度与后代喘息和哮喘发生轨迹的关系：日本环境与儿童研究（JECS）
Yukiko Nishihama,Tomohiko Isobe,Yukihiro Ohya et al.
Yukiko Nishihama et al.
Background: Asthma is a major chronic disease in childhood. Environmental factors such as air pollution, tobacco smoke, and dust have been associated with asthma prevalence. Lead (Pb) exposure can cause adverse health out...
The amphipod ecdysone receptor as a complementary tool for environmental risk assessment: from functional analysis to proof of concept study [0.03%]
等胸螠虫蜕皮激素受体在环境风险评估中的应用：从功能分析到概念验证研究
João Sousa,Anabelle Espeyte,Teresa Neuparth et al.
João Sousa et al.
Endocrine-disrupting chemicals (EDCs) pose significant risks to aquatic wildlife by disrupting hormonal signaling pathways, notably those mediated by nuclear receptors (NRs) - key regulators of endocrine processes. For decades, in vitro bio...
Co-exposure to polystyrene nanoparticles and cypermethrin regulates ferroptosis-mediated hepatic steatosis via the GPX4/SREBP1/SCD1 molecular axis [0.03%]
聚苯乙烯纳米颗粒和高效氯氟氰菊酯共暴露通过GPX4/SREBP1/SCD1分子轴调节铁死亡介导的肝脂肪变性
Fan Yu,Shihao Luo,Zhengrong Zhou et al.
Fan Yu et al.
Cypermethrin (CY), a pyrethroid insecticide, accumulated in aquatic environments and exertd toxic effects on aquatic organisms, impairing their development, nervous system, and immune function. Polystyrene nanoparticles (PS-NPs) readily ads...
Tracking resurgence of SARS-CoV-2 in Shenzhen, China, 2023-2025: evidence from wastewater, clinical, and climatic data [0.03%]
深圳2023-2025年新冠病毒再次流行追踪：来自废水、临床和气候数据的证据
Bincai Wei,Chen Du,Ziquan Lv et al.
Bincai Wei et al.
Wastewater-based epidemiology has emerged as a crucial tool for monitoring SARS-CoV-2 circulation beyond clinical testing. Despite the official end of the COVID-19 public health emergency, intermittent resurgences continue to challenge prep...