Unsaturated fatty acids mediate the bidirectional link between psoriasis and depression: Evidence from observational and mendelian randomization studies [0.03%]
不饱和脂肪酸介导银屑病和抑郁之间的双向关联：来源于观察性研究和孟德尔随机化研究的证据
Mengyang Chu,Biqing Tian,Jian Zhou et al.
Mengyang Chu et al.
Background: Depression is a prevalent and debilitating comorbidity of psoriasis. While the epidemiological association between the two conditions is well established, the causal relationship and the underlying biological ...
Modulation of proinflammatory but not regulatory cytokines by in vitro JAK inhibition in peripheral blood B-cells of patients with psoriatic arthritis [0.03%]
抑制 Jak 的体外调节会改变外周血 B 细胞中促炎细胞因子而非调节性细胞因子的表达（银屑病关节炎患者）
Antonio Tonutti,Natasa Isailovic,Francesca Motta et al.
Antonio Tonutti et al.
Epidermal deletion of Kindlin-1 drives matrix changes in the mouse skin and altered responses to ultraviolet radiation [0.03%]
表皮Kindlin-1缺失诱导小鼠皮肤基质变化并改变紫外线照射后的反应
Giovana Carrasco,Emily R Webb,Molly R Danks et al.
Giovana Carrasco et al.
Background: Kindler syndrome (KS) or Kindler epidermolysis bullosa (KEB) is a rare genetic autosomal skin fragility disorder with photosensitivity and abnormal pigmentation, with patients also having an increased risk of ...
Protective effects of the selective JAK2/3 inhibitor AG490 against ulcer formation following cutaneous ischemia-reperfusion injury [0.03%]
JAK2/3选择性抑制剂AG490对皮肤缺血再灌注损伤后溃疡形成的保护作用
Shintaro Saito,Akihiko Uchiyama,Takeshi Araki et al.
Shintaro Saito et al.
Background: Pressure ulcers are refractory skin ulcers that frequently develop at pressure sites in elderly individuals and those with reduced physical activity, and effective preventive strategies are urgently needed. Th...
Exploring the efficacy evaluation model for androgenic alopecia using hair organoids: Transcending conventional hair research [0.03%]
雄激素性脱发疗效评估模型的探索：利用毛囊器官芯片超越传统毛发研究
Seoyeon Kyung,Su Jin Lim,Kyung Eun Lee et al.
Seoyeon Kyung et al.
Background: The development of effective evaluation tools for anti-hair loss therapies is critical due to limitations in existing experimental systems. Hairy 3D skin models and hairy skin explants are not yet commercially...
A possible link between epidermal TRPV4 expression, osmolality, and itch in atopic dermatitis [0.03%]
特应性皮炎中皮肤TRPV4表达、渗透压与瘙痒的可能联系
Atsuko Kamo,Mao Hotta,Mitsutoshi Tominaga et al.
Atsuko Kamo et al.
Identification of novel small molecule compounds with readthrough activity in Nagashima-type palmoplantar keratosis [0.03%]
纳加岛型掌跖角化症读码活性新型小分子化合物的鉴定
Jin Teng Peh,Takato Sugiyama,Risa Nobuta et al.
Jin Teng Peh et al.
Background: Nagashima-type palmoplantar keratosis (NPPK), the most common form of hereditary palmoplantar keratodermas in East Asian populations, is caused by biallelic loss-of-function mutations in SERPINB7 such as p.Arg...
Treg cells as potential therapeutic targets for bullous pemphigoid: A review [0.03%]
调节性T细胞作为大疱性天疱疮的潜在治疗靶点：综述研究
Honghao He,Shiguang Peng,Xinyi Wei et al.
Honghao He et al.
Bullous pemphigoid (BP) is an autoimmune disease characterized by Bullous pemphigoid antigen 180(BP180) and Bullous pemphigoid antigen 230(BP230) autoantibodies production. Regulatory T cells (Tregs) are key cells for the maintenance of imm...
Eribulin promotes dendritic cell activation and migration in the murine tumor microenvironment [0.03%]
厄立替尼促进小鼠肿瘤微环境中的树突状细胞活化和迁移
Kazumasa Oya,Ko Matsuoka,Yoshiyuki Nakamura et al.
Kazumasa Oya et al.
Heparinoid and phospho-pyridoxal preserve tight junction integrity in human skin under oxidative stress [0.03%]
肝素样及焦磷酸吡哆醛通过抗氧化压力来维持人体皮肤紧密连接的完整性
Hiroki Sakamoto,Ryota Asahina,Momoyo Nishikawa et al.
Hiroki Sakamoto et al.