Hexarelin attenuates atherosclerosis via inhibiting LOX-1-NF-κB signaling pathway-mediated macrophage ox-LDL uptake in ApoE-/- mice [0.03%]
_hexarelin通过抑制LOX-1-NF-κB信号途径介导的巨噬细胞ox-LDL摄取缓解 apoE基因敲除小鼠的动脉粥样硬化
Xiu-Li Cheng,Fan Ding,De-Ping Wang et al.
Xiu-Li Cheng et al.
Growth hormone secretagogues (GHS) have been proved to exert protective effects on the cardiovascular system, while their potential beneficial effects on macrophages in atherosclerosis (AS) are rarely been clarified. This study aimed to dem...
Hexarelin attenuates atherosclerosis via inhibiting LOX-1-NF-κB signaling pathway-mediated macrophage ox-LDL uptake in ApoE-/- mice [0.03%]
Hexarelin通过抑制LOX-1-NF-κB信号通路介导的巨噬细胞ox-LDL摄取缓解动脉粥样硬化（Apoe基因敲除小鼠模型）
Xiu-Li Cheng,Fan Ding,De-Ping Wang et al.
Xiu-Li Cheng et al.
Growth hormone secretagogues (GHS) have been proved to exert protective effects on the cardiovascular system, while their potential beneficial effects on macrophages in atherosclerosis (AS) are rarely been clarified. This study aimed to dem...
The protective role of calcitonin gene-related peptide (CGRP) in high-glucose-induced oxidative injury in rat aorta endothelial cells [0.03%]
降钙素基因相关肽对高糖诱导的培养大鼠主动脉内皮细胞氧化损伤的保护作用
Yanjun Guo,Qin Zhang,Huilu Chen et al.
Yanjun Guo et al.
Endothelial dysfunction is considered to be an initial indicator in diabetes-induced macrovascular complications. Evidence has shown that CGRP is an important neuropeptide active in vascular system, especially in vasorelaxation. This study ...
The protective role of calcitonin gene-related peptide (CGRP) in high-glucose-induced oxidative injury in rat aorta endothelial cells [0.03%]
降钙素基因相关肽对高糖诱导的血管内皮细胞氧化损伤的保护作用
Yanjun Guo,Qin Zhang,Huilu Chen et al.
Yanjun Guo et al.
Endothelial dysfunction is considered to be an initial indicator in diabetes-induced macrovascular complications. Evidence has shown that CGRP is an important neuropeptide active in vascular system, especially in vasorelaxation. This study ...
Hypoxia augments NaHS-induced ANP secretion via KATP channel, HIF-1α and PPAR-γ pathway [0.03%]
缺氧增强NaHS诱导ANP分泌的KATP通道、HIF-1α和PPAR-γ通路作用
Lamei Yu,Weijian Li,Byung Mun Park et al.
Lamei Yu et al.
It has been reported that sodium hydrosulfide (NaHS) stimulated high stretch induced-atrial natriuretic peptide (ANP) secretion via ATP sensitive potassium (KATP) channel. KATP channel is activated during hypoxic condition as a compensatory...
Hypoxia augments NaHS-induced ANP secretion via KATP channel, HIF-1α and PPAR-γ pathway [0.03%]
缺氧增强NaHS诱导的ANP分泌的KATP通道、HIF-1α及PPAR-γ信号通路参与作用
Lamei Yu,Weijian Li,Byung Mun Park et al.
Lamei Yu et al.
It has been reported that sodium hydrosulfide (NaHS) stimulated high stretch induced-atrial natriuretic peptide (ANP) secretion via ATP sensitive potassium (KATP) channel. KATP channel is activated during hypoxic condition as a compensatory...
Irisin reverses insulin resistance in C2C12 cells via the p38-MAPK-PGC-1α pathway [0.03%]
irisin通过p38-MAPK-PGC-1α通路逆转C2C12细胞胰岛素抵抗
Xiao Ye,YiMin Shen,Chao Ni et al.
Xiao Ye et al.
Insulin resistance (IR) is a fundamental pathogenic factor shared by a myriad of metabolic disorders, including obesity and type 2 diabetes. The mechanism of IR is usually accompanied by mitochondrial dysfunction. Irisin has been proposed t...
Insulin-like peptide 5 fails to improve metabolism or body weight in obese mice [0.03%]
胰岛素样肽5不能改善肥胖小鼠的新陈代谢或体重
Alexander N Zaykov,Vasily M Gelfanov,Diego Perez-Tilve et al.
Alexander N Zaykov et al.
Insulin-like peptide 5 (INSL5) is a member of the insulin-like family of peptides. It has been reported to be orexigenic in rodent models of obesity with impaired glucose metabolism. We attempted to confirm this property as a first step in ...
Understanding interactions of Citropin 1.1 analogues with model membranes and their influence on biological activity [0.03%]
柑橘素1.1类似物与模型膜的相互作用及其对生物活性的影响
Nathalia Rodrigues de Almeida,Jonathan Catazaro,Maddeboina Krishnaiah et al.
Nathalia Rodrigues de Almeida et al.
The rapid emergence of resistant bacterial strains has made the search for new antibacterial agents an endeavor of paramount importance. Cationic antimicrobial peptides (AMPs) have the ability to kill resistant pathogens while diminishing t...
Intracerebroventricular administration of arginine vasotocin (AVT) induces anorexigenesis and anxiety-like behavior in goldfish [0.03%]
精氨酸血管紧张素(AVT)的脑室内给药可诱导金鱼食欲减退和类似焦虑的行为
Koh Araishi,Keisuke Watanabe,Takumi Yamazaki et al.
Koh Araishi et al.
Arginine vasotocin (AVT) is known as a neurohypophyseal hormone that regulates water- and mineral-balance in non-mammalian vertebrates. Recent studies revealed that AVT also exerts central effects on behavior. The goldfish has several merit...