Development of composite scales for assessing disease progression and treatment effects among patients with Parkinson's disease in a clinical trial setting [0.03%]
帕金森病临床试验中评定疾病进展和治疗效果的量表构建
Gil L&#x;Italien,Basia Rogula,Lauren C Powell et al.
Gil L&#x;Italien et al.
Background: The measures used to assess Parkinson's disease (PD) in clinical trials were developed for a broad spectrum of disease severity, limiting their ability to detect meaningful changes in early PD over a feasible ...
Parkinson's disease mild cognitive impairment with MRI evidence of cholinergic nucleus 4 degeneration: A new subtype? [0.03%]
帕金森病轻度认知障碍伴胆碱能核团4型磁共振证据：一种新的亚型吗？
Ahmed Negida,Hiba Z Vohra,Sarah K Lageman et al.
Ahmed Negida et al.
Background: Subtyping Parkinson's disease with mild cognitive impairment (PD-MCI) into clinically and pathologically homogeneous groups could improve clinical trials and enable personalized treatments. Cholinergic nucleus...
Expert commentary for "Neurophysiological findings in abdominal movements in CASPR2 encephalitis" [0.03%]
CASPR2脑炎腹部运动的神经生理发现专家评论
Pattamon Panyakaew,Pramod Kumar Pal
Pattamon Panyakaew
Apathy's hidden pathways: Psychosocial mediators of quality of life among people with early-onset Parkinson's disease [0.03%]
冷漠的隐秘途径——帕金森病早期患者的身心健康质量介导因素
Bradley McDaniels,Heerak Choi,Ripley Fricano et al.
Bradley McDaniels et al.
Introduction: Apathy is a highly prevalent non-motor symptom of Parkinson's disease (PD) and a major determinant of health-related quality of life (HRQoL). Its impact may be especially pronounced in early-onset PD (EOPD),...
Peripheral renin-angiotensin system and cognitive decline in Parkinson's disease patients without co-morbidities [0.03%]
无合并症的帕金森病患者外周肾素血管紧张素系统与认知下降的关系
Magdalena Kwaśniak-Butowska,Agnieszka Skrzypkowska,Agnieszka Konkel et al.
Magdalena Kwaśniak-Butowska et al.
Introduction: Peripheral renin angiotensin system (RAS) regulates blood pressure and is involved in inflammation and oxidative stress processes. We aimed to determine whether a peripheral RAS may contribute to cognitive i...
The genetic landscape of spinocerebellar ataxias in Taiwan: Insights from 876 genetically confirmed cases [0.03%]
台湾脊髓小脑共济失调的遗传谱系：来自876例基因确诊患者的启示
Shih-Chun Lan,Cheng-Tsung Hsiao,Kang-Yang Jih et al.
Shih-Chun Lan et al.
Background: Spinocerebellar ataxias (SCAs) are a group of inherited neurodegenerative disorders characterized by progressive cerebellar dysfunction and variable neurological features. Although the distribution and genetic...
Prevalence, characteristics, and clinical outcomes of Huntington's disease in Sub-Saharan Africa: A systematic review and meta-analysis [0.03%]
非洲撒哈拉以南地区亨廷顿舞蹈病的患病率、特征和临床结局：系统评价和荟萃分析
Nicholas Aderinto,Gbolahan Olatunji,Emmanuel Kokori et al.
Nicholas Aderinto et al.
Background: Huntington's disease (HD) is a rare neurodegenerative disorder with limited epidemiological data in Sub-Saharan Africa. This systematic review and meta-analysis aimed to estimate HD prevalence, describe demogr...
No anti-IgLON5 antibody in carefully diagnosed PSP patients with "atypical" or variant clinical features [0.03%]
无抗IgLON5抗体的PSP患者的临床特征分析
Anis Nadhirah Khairul Anuar,Ai Huey Tan,Jeremy Christopher Fernandiz et al.
Anis Nadhirah Khairul Anuar et al.
Background: "Atypical" features including REM sleep behaviour disorder (RBD) symptoms and visual hallucinations, and non-Richardson's syndrome (non-RS) variants, are increasingly recognized in progressive supranuclear pal...
Dyskinesia-hyperpyrexia syndrome due to introduction of continuous subcutaneous infusion of levodopa: A case report [0.03%]
左旋多巴连续皮下输注致运动障碍-高热综合征病例报告
Kanako Menjo,Rei Yasuda,Hiroki Yoshida et al.
Kanako Menjo et al.
The interplay between obesity and triglyceride-glucose index in modulating Parkinson's disease risk: A cross-sectional NHANES study of middle-aged and young adults [0.03%]
肥胖与三酰甘油-血糖指数在调节帕金森病风险中的相互作用：对中青年人群的横断面NHANES研究
Jincheng Ma,Mimi Li,Zhendong Lei
Jincheng Ma
Introduction: The triglyceride-glucose (TyG) index is a newly proposed biomarker of insulin resistance, and its relationship with Parkinson's disease (PD) remains to be studied, particularly among individuals with obesity...