Neurosyphilis in a patient with a corticobasal syndrome-like presentation and preserved dopamine transporter uptake [0.03%]
以皮质基底节综合征样表现为特征的神经梅毒一例及其多巴胺转运蛋白摄取量的保存价值研究
Kazuhiro Iwaoka,Tetsuro Kiyokawa,Kai Takahashi et al.
Kazuhiro Iwaoka et al.
Expert commentary for approach to a case of neuro-gonadal disorder: Perrault syndrome [0.03%]
神经系统和生殖系统异常病例解析——Perrault综合征患者一例
Susanne A Schneider
Susanne A Schneider
Tiago F Outeiro,Eduardo Tolosa
Tiago F Outeiro
Parkinson's disease (PD) is a complex heterogeneous neurodegenerative syndrome that is clinically defined. However, how it begins at the molecular and systems level remains unresolved. In this review, we cover selected evidence from neuropa...
Combined impact of depressive symptoms and mild cognitive impairment on Parkinson's disease progression [0.03%]
抑郁症状和轻度认知障碍对帕金森病进展的联合影响
Tianyu Hu,Chenqin Xu,Yilin Tang et al.
Tianyu Hu et al.
Objective: To investigate the joint associations of depressive symptoms and mild cognitive impairment (MCI) with longitudinal cognitive and clinical progression in Parkinson's disease (PD). ...
The association between social determinants of health and Parkinson's disease prevalence among U.S. adults: A cross-sectional study [0.03%]
美国成年人帕金森病患病率与健康社会决定因素之间的关联：一项横断面研究
Renjie Huang,Miao Huang,Rui Zhang
Renjie Huang
Background: Social determinants of health (SDOH) encompass the economic, social, and environmental conditions that shape health outcomes. While SDOH are increasingly recognized as fundamental drivers of chronic disease, t...
Association of early adjunctive dopaminergic therapy and 5-year mortality in Parkinson's disease: A nationwide cohort study [0.03%]
早发型多巴胺能药物联合治疗与帕金森病五年期死亡率的关联性全国队列研究
Seung Hyun Lee,Jooyoung Lee,Jang Hyun Bae et al.
Seung Hyun Lee et al.
Background: Although dopaminergic therapy improves motor symptoms in Parkinson's disease (PD), the association between initial treatment strategy and long-term survival remains unclear. ...
Alterations in regional cerebral perfusion in drug-induced Parkinsonism: Spatial covariance analyses of early-phase 18F-FP-CIT PET data [0.03%]
多巴胺能药物引起的帕金森综合征患者早期18F-FP-CIT PET成像的区域脑血流改变
Min Young Chun,Junyong Jang,Youngseok Choi et al.
Min Young Chun et al.
Background and objectives: Drug-induced Parkinsonism (DIP) develops in patients who are treated with drugs with D2 receptor-blocking activity, despite normal ranges of the striatal dopamine transporter (DAT) availability....
Longitudinal changes in DTI-ALPS index are associated with clinical progression and brainstem atrophy in spinocerebellar ataxia type 3 [0.03%]
脊髓小脑共济失调Ⅲ型中DTI-ALPS指数的纵向变化与临床进展和延髓萎缩有关
Zhe Long,Zhao Chen,Huirong Peng et al.
Zhe Long et al.
Background: The perivascular and neurofluid-related tissue environment is implicated in neurodegeneration, but its clinical relevance in spinocerebellar ataxia type 3 (SCA3) remains unclear. We investigated alterations in...
Health phenome of Parkinson's patients reveals prominent mood-sleep cluster [0.03%]
帕金森病患者的健康表型揭示了显著的情绪-睡眠亚群
Abby L Olsen,Joseph J Locascio,Idil Tuncali et al.
Abby L Olsen et al.
Introduction: Parkinson's disease (PD) patients have multiple co-morbidities, exposures, and medications. Our objective is to evaluate the complexity of features associated with PD in a study of 933 cases and 291 controls...
Frequency and outcome of PEG tube implantations in hospitalized Parkinson's disease patients [0.03%]
住院帕金森病患者的PEG置管频率及预后
Rachael M Burke,Ruina He,Hikaru Kamo et al.
Rachael M Burke et al.
Background: Dysphagia is a known complication of Parkinson's Disease (PD). Percutaneous endoscopic gastrostomy (PEG) tube placement is a therapy for select patients with dysphagia. There is a paucity of information on the...