Health phenome of Parkinson's patients reveals prominent mood-sleep cluster [0.03%]
帕金森病患者的健康表型揭示了显著的情绪-睡眠亚群
Abby L Olsen,Joseph J Locascio,Idil Tuncali et al.
Abby L Olsen et al.
Introduction: Parkinson's disease (PD) patients have multiple co-morbidities, exposures, and medications. Our objective is to evaluate the complexity of features associated with PD in a study of 933 cases and 291 controls...
Frequency and outcome of PEG tube implantations in hospitalized Parkinson's disease patients [0.03%]
住院帕金森病患者的PEG置管频率及预后
Rachael M Burke,Ruina He,Hikaru Kamo et al.
Rachael M Burke et al.
Background: Dysphagia is a known complication of Parkinson's Disease (PD). Percutaneous endoscopic gastrostomy (PEG) tube placement is a therapy for select patients with dysphagia. There is a paucity of information on the...
The acute effects of a single session of intermittent hypoxia on blood biomarker concentrations and sleep parameters in people with Parkinson's disease: A randomized, double-blind, crossover trial [0.03%]
间断性低氧单次暴露对帕金森病患者血液生物标志物浓度和睡眠参数急性影响的随机双盲交叉试验
Murilo Henrique Faria,Carlos Augusto Kalva-Filho,Vinicius Oliveira Queiroz et al.
Murilo Henrique Faria et al.
Background: People with Parkinson's disease (pwPD) exhibit sleep and blood biomarker alterations. Intermittent normobaric hypoxia (IH) may promote neuroprotection, but acute effects remain unclear. We aimed to investigate...
A framework for multidisciplinary management of autonomic dysfunction in Parkinson disease [0.03%]
帕金森病自主神经功能障碍的多学科管理框架
Cameron Miller-Patterson,Delaram Safarpour,Katherine Longardner et al.
Cameron Miller-Patterson et al.
Autonomic dysfunction (AD) is present in nearly all people with Parkinson disease (PD), contributing to tremendous morbidity and mortality. Highly variable presentations including cardiovascular, gastrointestinal, urogenital, and thermoregu...
MANAGE-PD and clinician recommendations for device-aided therapy in Parkinson's disease: Insights from a Turkish tertiary movement disorders cohort [0.03%]
土耳其三级运动障碍病区帕金森病的自我管理和临床医生对辅助治疗建议的见解
Halil Onder,Zehra Yavuz,Selçuk Comoglu
Halil Onder
Introduction: The MANAGE-PD tool was developed to identify patients with Parkinson's disease (PD) who may require treatment optimization or consideration of device-aided therapies (DAT). However, real-world studies have s...
Diagnostic odyssey in type B Kufs disease: From autoimmune encephalitis mimicry to a frontotemporal dementia phenotype [0.03%]
Kufs病型B的诊断之旅:从自身免疫性脑炎假象到额颞叶痴呆表型
Sayooja Sachithanandan,Kiren Koshy,Syam Krishnan et al.
Sayooja Sachithanandan et al.
A novel SGCE splicing variant in a Chinese family with Myoclonus-Dystonia: Rare phenotype and phenotypic variability [0.03%]
中国MYD患者家系中新型SGCE可变剪接变异及其罕见表型和表型变异研究
Xiaoxue Peng,Jilin Yu,Xiaoyang Lei et al.
Xiaoxue Peng et al.
Efficacy of citicoline as an add-on therapy in Parkinson's disease: a randomized, double-blind trial [0.03%]
尼麦角碱作为辅助治疗改善帕金森病功效的随机双盲试验
Massimo Marano,Andrea Pilotto,Giancarlo Logroscino et al.
Massimo Marano et al.
Background: Citicoline is a promising therapeutic option for improving both motor and non-motor symptoms in Parkinson's disease (PD) beyond levodopa and other standard dopaminergic treatments. ...