Dimorphic substrates, monomorphic outcomes: Social behavior neural circuit tuning in social monogamy [0.03%]
Varvara A Shvareva,Kristen M Berendzen,Kevin J Bender et al.
Varvara A Shvareva et al.
Social behaviors are dramatically influenced by variations in mating systems that shape sex differences in the neural substrates underlying such displays. In polygamous species, distinct evolutionary pressures on males and females produce p...
Postnatal sensory experience and barrel cortex alterations anticipate autistic traits in a mouse model of CDKL5 deficiency disorder [0.03%]
产后感觉体验和桶状皮层改变预测CDKL5缺陷症小鼠模型自闭症样特征
Alessandra Raspanti,Riccardo Pizzo,Antonia Gurgone et al.
Alessandra Raspanti et al.
Autistic traits may arise from atypical sensory experience during postnatal life, but whether there is a causal link between defects in cortical circuitry in the brain, altered sensory processing and social behavior remains unknown. Here, w...
Neural Selection in Corticothalamocortical Loops: Heterogeneity as a Computational Resource [0.03%]
皮层-丘脑-皮层环路中的神经元选择：异质性作为一种计算资源
Brandon R Munn,Eli J Müller,Christopher J Whyte et al.
Brandon R Munn et al.
Neuroscience has long relied on (typically binary) categorisations to manage the complexity of brain organisation. Yet growing anatomical and physiological evidence reveals that these dichotomies artificially partition systems that are inhe...
Oscar Woolnough,Elliot Murphy,Stanislas Dehaene et al.
Oscar Woolnough et al.
As you read this sentence, you integrate meanings of individual words into complex, higher-order representations. In addition to the core language network (LN), this dynamic process recruits other domain-general networks such as the default...
Afferent and efferent projections of parvalbumin-expressing neurons in the thalamic reticular nucleus of the mouse [0.03%]
小鼠丘脑网状核_parvalbumin阳性神经元的传入和传出投射
Yi-Yao Li,Xin-Tong Qiu,Xiao Ren et al.
Yi-Yao Li et al.
The whole-brain connectivity of thalamic reticular nucleus (TRN) parvalbumin-positive (PV+) neurons has been characterized at the population level, yet their single-cell projectome diversity and the corresponding electrophysiological hetero...
Astrocytic α7 nicotinic acetylcholine receptors play an essential role in regulating glutamate dynamics and memory flexibility in the hippocampus [0.03%]
海马星形胶质细胞α7烟碱乙酰胆碱受体在调节谷氨酸动力学和记忆灵活性中的重要作用
Maria Rosaria Tropea,Marcello Melone,Roberto Piacentini et al.
Maria Rosaria Tropea et al.
Astrocytes regulate hippocampal excitatory transmission by controlling glutamate dynamics, yet the contribution of cholinergic signaling to these processes remains poorly understood. Here, we investigated the role of astrocytic α7 nicotini...
Deletion of Fbxo25 causes excessive repetitive behavior, impaired recognition memory, reduced dendritic complexity, and aberrant protein expression in mice [0.03%]
Fbxo25基因缺失导致小鼠重复行为过度、识别记忆受损、树突复杂度下降和蛋白表达异常
Szu-Yu Lin,Ho-Ching Chang,Ya-Han Chang et al.
Szu-Yu Lin et al.
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and restricted repetitive behaviors. Genetic studies have implicated chromosomal microdeletions in the 8p23.2-pter region in A...
Neuropsychiatric Disease Mechanisms and Interventions. from 22q11.2 Deletion Syndrome Experimental Studies [0.03%]
22q11.2缺失综合征的精神神经疾病发病机制和干预实验研究
Prakash Devaraju
Prakash Devaraju
A high genetic predisposition for neuropsychiatric disorders, such as schizophrenia and autism spectrum disorders (ASDs), is 22q11.2 deletion syndrome (22q11DS), caused by a hemizygous microdeletion in the q-arm of human chromosome 22. The ...
Stefano T Censi,Alberto Granzotto,Stefano L Sensi
Stefano T Censi
Sleep remains a complex and only partially understood neurophysiological process, with current theories often fragmented across electrophysiological, metabolic, and phenomenological domains. In this paper, we propose an advanced and integra...
Cynthia Rais,Maxime Maheu,J Simon Wiegert
Cynthia Rais
Neuronal representations of the world are dynamic. A striking example is the rapid remapping of the hippocampal spatial code, which occurs even when the environment and behavior remain unchanged. CA3 input to CA1 has been shown to exert a k...