Adaptation of eating behaviour to reduced dietary protein intake in rats: influence of the amount of protein and amino acid composition in the diet [0.03%]
蛋白质摄入量减少时大鼠摄食行为的适应:饮食中蛋白质的数量和氨基酸组成的影响
Tristan Dadillon,Gaëlle Champeil-Potokar,Marjorie Gourru et al.
Tristan Dadillon et al.
Reducing meat consumption is encouraged to improve diet environmental sustainability. It results in reducing protein intake, and this can have consequences on eating behaviour. To better characterise these consequences, six-week-old male Wi...
Sweet stimuli induce cephalic phase insulin release to varying degrees in humans [0.03%]
甜味刺激物会不同程度地诱导人体产生cephalic相胰岛素分泌
Alexa J Pullicin,Juyun Lim
Alexa J Pullicin
Previous work has shown that oral stimulation with glucose and glucose-containing carbohydrates induces cephalic phase insulin release (CPIR), and that inhibiting the sweet taste receptor, T1R2+T1R3, attenuates this effect in humans. It rem...
Metabolic changes explain how training mitigates the reduction in strength caused by sleep restriction [0.03%]
代谢变化解释了训练如何缓解睡眠限制导致的力量下降
Paulo Drs Nosé,Lila M Oyama,Gustavo Gomes de Araujo et al.
Paulo Drs Nosé et al.
Sleep is crucial for maintaining physiological and cognitive functions, including athletic performance; yet, nearly half of adults in Western countries experience sleep restriction. While human studies demonstrate that sleep restriction imp...
Synergistic effects of capsaicin and ketamine on the depression-like behaviors of animals subjected to the chronic unpredictable mild stress protocol [0.03%]
辣椒素和氯胺酮对慢性轻度不可预测应激小鼠的协同抗抑郁作用研究
Irving S Aguilar-Martínez,José L Góngora-Alfaro,Ricardo A Navarro-Polanco et al.
Irving S Aguilar-Martínez et al.
A significant percentage of depression patients are resistant to pharmacological treatments, highlighting the need for novel antidepressant strategies. Ketamine, an NMDA receptor antagonist, produces rapid antidepressant effects and is effe...
Analysis of Nonclinical Safety and Corneal Pain-Inducing Potential of Amentoflavone (AMT) in Adult Zebrafish (Danio rerio) [0.03%]
异黄酮(AMT)非临床安全和引起成年斑马鱼角膜疼痛潜力的分析研究
Lucas Soares Frota,Francisco Ernani Alves Magalhães,Daniela Braga de Sousa et al.
Lucas Soares Frota et al.
Corneal pain affects the outer layer of the eye and can result from injuries, infections, autoimmune diseases, or dry eye syndrome. Amentoflavone (AMT), a natural biflavonoid used in traditional Chinese medicine, is known for its anti-infla...
Gut Microbiota Mediates the Protective Effects of SGLT-2 Inhibitors on Bipolar Disorder: an intermediary Mendelian randomization study [0.03%]
肠道微生物介导SGLT-2抑制剂对双向情感障碍的保护作用:中介性孟德尔随机化研究
Yaofeng Wang,Yunchang Yang,Yunqin Sun
Yaofeng Wang
Background: Bipolar disorder (BD), with a global prevalence of approximately 1%, is characterized by mood swings and social impairment, and involves factors such as genetics, brain structure abnormalities, and gut-brain a...
Sex differences in cortisol levels and their relationship with memory and negative affectivity in patients with drug-resistant epilepsy [0.03%]
药物难治性癫痫患者皮质醇水平的性别差异及其与记忆和负向情绪的关系
Paula Tormos-Pons,Irene Cano-López,Judit Catalán-Aguilar et al.
Paula Tormos-Pons et al.
Drug-resistant epilepsy can be considered a chronic stress condition characterized by uncontrollable seizures together with cognitive and affective alterations. Epilepsy and its treatments affect men and women differently, potentially due t...
Molecular Mechanisms Underlying Obesity-Induced Memory Dysfunction: A Comprehensive Narrative Review [0.03%]
肥胖引起的记忆障碍分子机制:全面叙述性综述
Ahmad Golkar,Fateme Razazpour,Mohammad Dalfardi et al.
Ahmad Golkar et al.
Obesity has reached epidemic proportions globally and is increasingly recognized as a significant risk factor for cognitive decline and memory impairment. This comprehensive narrative review synthesizes current evidence on the molecular mec...
Female mantled howler monkeys (Alouatta palliata mexicana) alter their diet in terms of tannin consumption according to their reproductive stage [0.03%]
雌性吼猴根据其生殖阶段调整单宁的摄取量
Anna Gisbrecht,John F Aristizabal,Erandi Susana Hernández-Arriaga et al.
Anna Gisbrecht et al.
Tannins (TN) are polyphenolic compounds primarily known to be involved in the defense mechanism of vascular plants against herbivory. Their excessive consumption can cause damage to an animal's digestive tract; yet, with moderate consumptio...
Adolescent Swimming Exercise Induces Systemic Adaptations and Molecular Changes in the Rat Cerebral Cortex [0.03%]
青春期游泳锻炼引起大鼠大脑皮层的全身性适应及分子改变
Douglas Buchmann Godinho,Leandro Machado Severo Feiteiro,João Victor de Mattos Mautone Pedroso et al.
Douglas Buchmann Godinho et al.
Objective: Adolescence is a critical developmental window during which physical activity can exert long-lasting effects on brain function and health. However, the molecular impact of structured exercise during this period...