Methanol-induced metabolic disturbances in protein expression in Pichia pastoris: A review of the interaction between amino acid synthesis and higher alcohol pathways [0.03%]
甲醇引起毕赤酵母蛋白表达的代谢紊乱:关于氨基酸合成与高阶酒精路径相互作用的综述
Lifen He,Danling Tang,Fan Feng et al.
Lifen He et al.
Pichia pastoris is a prominent host for recombinant protein production, utilizing the methanol-inducible Alcohol Oxidase 1 (AOX1) promoter to express thousands of heterologous proteins. However, methanol induction, while driving high-level ...
Emerging strategies for enhanced glutathione biosynthesis and its biomedical applications [0.03%]
谷胱甘肽生物合成的新兴策略及其在生物医学中的应用
Yajie Wang,Ruixue Ma,Jia Zhou et al.
Yajie Wang et al.
Glutathione (GSH), a ubiquitous bioactive tripeptide, plays a central role in antioxidant defense, detoxification, and cellular metabolism. This review highlights advanced strategies to enhance GSH production, emphasizing strain improvement...
Optical, structural, and antifungal features of nanosilver borate bioactive glass synthesized using gamma rays on the subsistence of Candida albicans and Candida tropicalis [0.03%]
γ射线合成纳米银硼酸生物活性玻璃的光学、结构和抗真菌特性及其在白色念珠菌和热带假丝酵母存活中的作用
E M Abou Hussein,Rasha Mohammad Fathy
E M Abou Hussein
A New glass system with a composition of; 50.3 B2O3+ 21 CaO + 8 MgO + 8 K2O + 8 Na2O+ 4 P2O5 + 0.7 Nano Ag2O, was prepared by the traditional melting technique. Some of its structural, optical, and physical characteristics were investigated...
Production of High-Nutrient Protein Sources by Pre-Secondary Solid-State Fermentation of Functional Microbiota (Pre-Sec-SSF-FM) from Dehulled Chinese Distillers Grains [0.03%]
基于去皮玉米酒精糟粕的预次级固态发酵功能微生物生产高营养蛋白源技术(Pre-Sec-SSF-FM)
Lian Zhang,Xiaojuan Shen,Zhi Wang et al.
Lian Zhang et al.
Chinese distillers grains (CDGs) are used as low-cost feed additives, because they have issues such as high crude fiber content (> 24%), low crude protein content (< 17%), and low digestibility (< 16%). This study aimed to evaluate whether ...
Beini Sun,Gengqiang Cao,Tian Gan et al.
Beini Sun et al.
Precise targeted drug screening is the key to improve the efficiency of tumour targeted therapy. This report presents a live cell FRET two-hybrid assay-based targeted drug screening method (FRET-HBTDS). In FRET-HBTDS, the cells co-expressin...
Halotolerant black yeast Neophaeotheca triangularis as a source of melanin [0.03%]
耐盐黑酵母Neophaeothecaltricularis作为一种花青素来源
Mercedes Peña,Patricia Gómez-Villegas,Jose Prados et al.
Mercedes Peña et al.
Archaea and bacteria are the most studied extremophiles, but fungi also demonstrate remarkable tolerance, particularly in hypersaline environments such as solar salterns. Among salt-adapted fungi, black yeasts have been shown to be adapted ...
Differential metabolic reprogramming due to nitrogen starvation leads to remobilization of storage metabolites in microalgal strains [0.03%]
微藻菌株由于氮饥饿而产生的不同的代谢重组导致储藏物质的再利用化
Lidiane Covell,Mariana Machado,Marcelo Gomes Marçal Vieira Vaz et al.
Lidiane Covell et al.
Microalgal stress-related responses to nitrogen (N) deprivation are determined by genetically defined metabolic changes, which are further influenced by cultivation and nutritional conditions. In this study, we evaluated the metabolic respo...
Ternary Deep Eutectic Solvent (T-CuCl2-EG) for Lignin Removal from Corn straw [0.03%]
三元深共熔溶剂(T-CuCl2-EG)脱除玉米秸秆中的木质素
Kang Zhao,Sha-Sha Zhao,Quan-Wei Liu et al.
Kang Zhao et al.
To address the challenge of lignin removal while preserving cellulose in lignocellulosic biomass valorization, this study developed a novel ternary deep eutectic solvent (DES) system composed of triethylbenzyl ammonium chloride (T, as hydro...
Corrigendum to "Substitution of reactive centre loop residues from C1 esterase inhibitor increases the inhibitory specificity of alpha-1 antitrypsin for plasma kallikrein" [J. Biotechnol. 405 (2025) 205-214] [0.03%]
“C1酯酶抑制剂反应中心环残基的置换增加α1抗胰蛋白酶对血浆激肽释放酶的特异性[J. Biotechnol. 405 (2025) 205-214]”一文的勘误通知
Sangavi Sivananthan,S Ameer Ahmed,Ammaar M Baig et al.
Sangavi Sivananthan et al.
Published Erratum
Journal of biotechnology. 2025 Nov 8:409:182. DOI:10.1016/j.jbiotec.2025.11.003 2025
High temperature drives torularhodin-dominant carotenoid overaccumulation in Rhodosporidiobolus odoratus XQR via coordinated transcriptomic-metabolomic reprogramming [0.03%]
高温驱动酵母毕赤酵母耐醇酵母中主要为torularhodin类胡萝卜素的积累通过转录组-代谢组联合再编程实现
Die Zhao,Chunji Li,Nan Zeng et al.
Die Zhao et al.
Carotenoids are bioactive pigments widely used in food, pharmaceutical, and cosmetic industries. Rhodosporidiobolus odoratus co-produces commercially significant carotenoids, including β-carotene, torulene, and torularhodin. This study aim...