Enhancing Oxidative Stress Defense to Improve Docosahexaenoic Acid Production in Schizochytrium sp. HX-308 [0.03%]
通过增强氧化压力防御提高Schizochytrium sp. HX-308中二十二碳六烯酸的产量
Chunxiao Yan,Shuai Zhang,Zhihao Huang et al.
Chunxiao Yan et al.
As an excellent host for docosahexaenoic acid (DHA) biosynthesis, Schizochytrium sp. still faces inherent limitations in DHA yield due to oxidative damage induced by reactive oxygen species (ROS). To effectively reduce the ROS levels, the o...
Next level of p-phenylene diisothiocyanate-based covalent immobilization of β-D-galactosidase: Technical optimization as an application [0.03%]
基于p-亚苯基二异硫氰酸酯的β-D-半乳糖苷酶共价固定化的新水平：作为应用的技术优化
Tabea L Boehme,Bernadette Straub,Anja Oberle et al.
Tabea L Boehme et al.
In this study, a continuous lactose hydrolysis process in a fixed-bed reactor was developed using β-galactosidase covalently immobilized on resin beads via 1,4-phenylenediisothiocyanate (PDC) as linker. Process conditions, including temper...
Antibacterial effects and mechanisms of fisetin-β-cyclodextrin complex under UVA light against Escherichia coli O157:H7 [0.03%]
飞斯汀-β环糊精复合物在UVA照射下对O157:H7的抑菌效果及机理研究
Tao Liu,Yuzhang Zhu,Jiahui Wang et al.
Tao Liu et al.
The development of natural product photosensitizers was a critical cornerstone for applying photodynamic antimicrobial technology in the food industry. The objective of this study was to fabricate complex of fisetin-β-cyclodextrin (FIT-β-...
Increasing the chiral purity of cellulosic L-lactic acid by D-Lactate oxidase-catalyzed oxidation in engineered lactic acid bacterium Pediococcus acidilactici [0.03%]
工程益生菌希瓦氏菌催化D-乳酸氧化提高纤维素基L-乳酸光学纯度
Jiao Liu,Chaolong Qu,Bin Zhang et al.
Jiao Liu et al.
Trace amounts of D-lactic acid derived from lignocellulose feedstock and nitrogen additives frequently reduces the chiral purity of L-lactic acid below the polymerization standard during biorefinery fermentations. The spontaneous D-lactic a...
Enhancing heterotrophic lutein production in Chlorella protothecoides through combined phytohormone and nitrogen strategies [0.03%]
通过结合植物激素和氮策略增强小球藻中的异养番茄红素生产
Jiaxin Li,Weiyang Zhao,Yunlei Fu et al.
Jiaxin Li et al.
Large-scale production of microalgal lutein faces challenges due to limited biomass and lutein content. In this work, we developed an exponential fed-batch model to achieve heterotrophic high-density growth of Chlorella protothecoides CS-41...
High specificity of MsmCAR toward 4-hydroxyvaleric acid enables efficient 1,4-pentanediol production from biomass-derived levulinic acid [0.03%]
Msmcar 对 4-羟基戊酸的高特异性使其能够高效地利用生物基 levylic 酸生产 1,4-戊二醇
Suhye Choi,Seung Hun Lee,Yunyeong Kim et al.
Suhye Choi et al.
Alkanediols are industrial compounds with diverse applications. However, the biological production of C5 diols is limited by the low substrate specificity and efficiency of carboxylic acid reductases (CARs) toward short to medium-chain subs...
Experimental immobilization of Clostridium histolyticum collagenases on green-synthesized CuO nanoparticles supported by bioinformatics analysis [0.03%]
生物信息学分析辅助的绿色合成CuO纳米颗粒固定化胶原酶试验研究
Farzaneh Barati,Fakhrisadat Hosseini,Parinaz Ghadam et al.
Farzaneh Barati et al.
Enzymes are widely used in various industries due to their eco-friendly nature, high selectivity, and ability to operate under mild conditions. However, large-scale applications are often hindered by challenges such as limited stability, hi...
Directional lactic acid production could mitigate antibiotic and ARGs pollution [0.03%]
定向乳酸生产或可缓解抗生素和ARG污染问题
Fubin Yin,Tianjing Lian,Haoying Qu et al.
Fubin Yin et al.
The technology of directional lactic acid production (DLAP) for animal manure is an innovative way of value-added utilization, but the influence of residual antibiotics in animal manure on the DLAP is still unclear, especially the degradati...
Sodium alginate-immobilized epoxide hydrolase: A multifaceted strategy for enhanced stability, reusability, and catalytic performance [0.03%]
海藻酸钠固定化环氧水解酶：提高稳定性和催化性能的多方位策略
Zongzhong Yu,Meinan Zhu,Xiao Gu et al.
Zongzhong Yu et al.
Immobilized macromolecular enzymes effectively address critical challenges including environmental sensitivity, thermal instability, and non-reusability, thereby establishing the fundamental and practical significance of enzyme immobilizati...
Human beta-defensin 3-functionalized Fe/GMP nanozyme for multifunctional antimicrobial and anticancer activity against Helicobacter pylori-associated gastrointestinal cancer [0.03%]
人β-防御素3功能化铁/瓜尔胶纳米酶对幽门螺杆菌相关胃肠道癌症的多功能抗菌和抗肿瘤活性
Yoganathan Kamaraj,Veenayohini Kumaresan,Jinhao Hu et al.
Yoganathan Kamaraj et al.
Background: The rising incidence of Helicobacter pylori-associated infections and colorectal cancer necessitates multifunctional therapeutics targeting both microbial and tumor pathologies. However, antimicrobial peptides...