Resveratrol and resveratrol nano-delivery systems in the treatment of inflammatory bowel disease [0.03%]
白藜芦醇和白藜芦醇纳米递送系统在治疗炎症性肠病中的作用
Vemana Gowd,Kanika,Chandrashekhar Jori et al.
Vemana Gowd et al.
Inflammatory bowel disease (IBD) is a chronic disorder associated with the inflammation in the digestive tract. The exact cause of IBD is unknown; nevertheless, in IBD, the homeostasis of key regulatory factors involved in intestinal immuni...
Alleviation of cognitive deficits via upregulation of chondroitin sulfate biosynthesis by lignan sesamin in a mouse model of neuroinflammation [0.03%]
愈创木塞米通过上调硫酸软骨素生物合成缓解神经炎症小鼠模型的认知障碍
Jun Yamada,Shoichiro Maeda,Mariko Soya et al.
Jun Yamada et al.
Lignans are plant-derived compounds that act as partial estrogen agonists. Chondroitin sulfate proteoglycans (CSPGs) represent one of the major components of the extracellular matrix. Here we aimed to understand the role of sesamin (SES), a...
Sodium butyrate modulates blood pressure and gut microbiota in maternal tryptophan-free diet-induced hypertension rat offspring [0.03%]
丁酸钠调节无色氨酸饮食诱导的母体高血压大鼠后代血压和肠道菌群
Chien-Ning Hsu,Hong-Ren Yu,I-Chun Lin et al.
Chien-Ning Hsu et al.
Maternal nutrition, gut microbiome composition, and metabolites derived from gut microbiota are closely related to the development of hypertension in offspring. A plethora of metabolites generated from diverse tryptophan metabolic pathways ...
Obesity, the other pandemic: linking diet and carcinogenesis by epigenetic mechanisms [0.03%]
肥胖的另一场流行病：通过表观遗传机制连接饮食和癌症发生率
Eduardo Izquierdo-Torres,Andrés Hernández-Oliveras,Dalia Lozano-Arriaga et al.
Eduardo Izquierdo-Torres et al.
Both obesity and cancer are complex medical conditions that are considered public health problems. The influence of obesity on the predisposition to develop various types of cancer has been observed in a wide variety of studies. Due to thei...
The influence of phytochemicals on cell heterogeneity in chronic inflammation-associated diseases: the prospects of single cell sequencing [0.03%]
植物化学物质对慢性炎症相关性疾病细胞异质性影响的研究前景——单细胞测序技术的应用价值
Fan Xiao,Mohamed A Farag,Jianbo Xiao et al.
Fan Xiao et al.
Chronic inflammation-associated diseases include, but is not limited to cardiovascular disease, cancer, obesity, diabetes, etc. Cell heterogeneity is a prerequisite for understanding the physiological and pathological development of cell me...
The role of orally ingested milk fat globule membrane on intestinal barrier functions evaluated with a suckling rat pup supplementation model and a human enterocyte model [0.03%]
口服摄入的乳脂肪球膜对肠道屏障功能的作用：小鼠补充模型与人体肠细胞模型的研究
Rulan Jiang,Xiaogu Du,Lauren Brink et al.
Rulan Jiang et al.
Milk fat globule membrane (MFGM), the membrane surrounding secreted fat droplets in milk, contains components involved in a wide range of bioprocesses including cell proliferation and differentiation. The intestine is relatively immature an...
Effects of dietary restriction on hepatic sulfur-containing amino acid metabolism and its significance in acetaminophen-induced liver injury [0.03%]
饮食限制对肝脏含硫氨基酸代谢的影响及其在乙酰氨基酚致肝损伤中的意义
Doyoung Kwon,Seung Won Son,Sou Hyun Kim et al.
Doyoung Kwon et al.
Dietary restriction (DR) has been revealed to have health benefits as it induces reduction in oxidative stress. Glutathione (GSH), an important cellular antioxidant, is increased in rodent livers owing to DR; however, the exact mechanism an...
Green tea catechin EGCG could prevent obesity-related precocious puberty through NKB/NK3R signaling pathway [0.03%]
绿茶儿茶素EGCG通过NKB/NK3R信号通路预防肥胖相关性早熟
Qiuyun Gu,Xiaodi Wang,Luyao Xie et al.
Qiuyun Gu et al.
This study aimed to explore the potential regulatory pathways of (-)-epigallocatechin-3-gallate (EGCG) in preventing obesity-related precocious puberty. A retrospective analysis on the impact of EGCG on puberty onset in obese girls was cond...
Randomized Controlled Trial
The Journal of nutritional biochemistry. 2022 Oct:108:109085. DOI:10.1016/j.jnutbio.2022.109085 2022
Synergistic anti-inflammatory effects and mechanisms of the combination of resveratrol and curcumin in human vascular endothelial cells and rodent aorta [0.03%]
白藜芦醇与姜黄素联合抗炎的协同作用及机制研究：人血管内皮细胞和小鼠主动脉模型中的作用及机制探讨
Lijuan Zhang,Xiaoyong Wang,Hongwei Si
Lijuan Zhang
Chronic increased pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α) play critical roles in the development of endothelial dysfunction and therefore induce cardiovascular disease. Although phytochemicals have the potent...
The PNPLA3 variant I148M reveals protective effects toward hepatocellular carcinoma in mice via restoration of omega-3 polyunsaturated fats [0.03%]
PNPLA3变异体I148M通过恢复ω-3多不饱和脂肪在小鼠中对肝细胞癌具有保护作用
Eleonora Patsenker,Veera Raghavan Thangapandi,Oskar Knittelfelder et al.
Eleonora Patsenker et al.
Alcohol consumption and high caloric diet are leading causes of progressive fatty liver disease. Genetic variant rs738409 in patatin-like phospholipase domain-containing protein 3 (PNPLA3 rs738409 C>G) has been repeatedly described as one o...