Supplementation of polyphenol-rich grapes attenuates colitis, colitis-associated colon cancer, and disease-associated dysbiosis in mice, but fails to mitigate colitis in antibiotic-treated mice [0.03%]
富含多酚的葡萄补充剂可通过减轻小鼠结肠炎，相关结肠癌及疾病相关的菌群失调来改善肠道健康，但在抗生素处理的小鼠中无法缓解结肠炎症状
Yiying Zhao,Cindy Nakatsu,Yava Jones-Hall et al.
Yiying Zhao et al.
Polyphenols are known to interact with gut microbes that play key roles in maintaining gut health, but the role of gut microbiota modulation by polyphenols in mitigating colonic diseases is not fully established. We hypothesize that the int...
Daytime restricted feeding promotes circadian desynchrony and metabolic disruption with changes in bile acids profiles and gut microbiota in C57BL/6 Male Mice [0.03%]
限食引起的昼夜节律失调和代谢紊乱以及对胆汁酸轮廓和肠道微生物群的影响
Yuan Cui,Shilan Li,Yan Yin et al.
Yuan Cui et al.
Fasting/feeding cycles regulate clock-lipid-bile acid (BA) metabolic homeostasis, and gut microbiota also participates in connecting circadian rhythms with BA metabolism. To investigate the cyclical nature of microbial-metabolism-host inter...
Visceral and body adiposity are negatively associated with vitamin A nutritional status independently of Body Mass Index and recommended intake of vitamin A in Brazilian Women [0.03%]
内脏脂肪和身体脂肪与巴西女性维生素A营养状况负相关性独立于体质指数和维生素A推荐摄入量
Amanda Ribamar,Sabrina Cruz,Cláudia Bento et al.
Amanda Ribamar et al.
Vitamin A (VA) has a negative association with body mass index (BMI) since it is involved in the regulation of body adiposity via nuclear receptors. However, few studies have investigated the relationship between VA nutritional status and t...
Analytical methods for 25-hydroxyvitamin D: advantages and limitations of the existing assays [0.03%]
25-羟基维生素D的检测方法：现有检测手段的优势与不足
Aparna Tripathi,MohdShamshad Ansari,Prajakta Dandekar et al.
Aparna Tripathi et al.
Vitamin D plays an important role in the absorption of calcium and phosphorus, bone metabolism. Various analytical methods are being used to measure the circulating vitamin D levels in the blood. Among all vitamin D metabolites, 25 hydroxyv...
Effect of processing on the anti-inflammatory efficacy of cocoa in a high fat diet-induced mouse model of obesity [0.03%]
加工方法对高脂饮食诱导的肥胖小鼠模型中可可抗炎功效的影响
Daphne K Weikart,Vijaya V Indukuri,Kathryn C Racine et al.
Daphne K Weikart et al.
Obesity causes inflammation which may lead to development of co-morbidities like cardiovascular diseases. Cocoa is a popular food ingredient that has been shown to mitigate obesity and inflammation in preclinical models. Cocoa typically und...
1α,25-dihydroxyvitamin D reduction of MCF10A-ras cell viability in extracellular matrix detached conditions is dependent on regulation of pyruvate carboxylase [0.03%]
1α,25-二羟基维生素D通过调节丙酮酸羧化酶降低无细胞外基质粘附的MCF10A-RAS细胞活力
Madeline P Sheeley,Violet A Kiesel,Chaylen Andolino et al.
Madeline P Sheeley et al.
An emerging hallmark of cancer is cellular metabolic reprogramming to adapt to varying cellular environments. Throughout the process of metastasis cancer cells gain anchorage independence which confers survival characteristics when detached...
Genistein attenuates memory impairment in Alzheimer's disease via ERS-mediated apoptotic pathway in vivo and in vitro [0.03%]
染料木素通过体内和体外实验中的内质网应激介导的凋亡途径来缓解阿尔茨海默病引起的记忆损伤
Huawu Gao,Xin Lei,Shu Ye et al.
Huawu Gao et al.
Genistein (GS), an isoflavone compound found in soybean, plays a neuroprotective role in Alzheimer's disease (AD). However, the mechanism of its action remains unclear. Herein, binding ability between GS and GRP78 was predicted by molecular...
Maternal soybean diet on prevention of obesity-related breast cancer through early-life gut microbiome and epigenetic regulation [0.03%]
大豆饮食通过生命早期肠道微生态和表观遗传调控预防肥胖相关乳腺癌研究
Min Chen,Shizhao Li,Itika Arora et al.
Min Chen et al.
Overnutrition-induced obesity and metabolic dysregulation are considered major risk factors contributing to breast cancer. The origin of both obesity and breast cancer can retrospect to early development in human lifespan. Genistein (GE), a...
Dietary iron modulates hepatic glucose homeostasis via regulating gluconeogenesis [0.03%]
铁元素摄入量通过调节糖异生作用调控肝脏葡萄糖稳态
Jiahui Li,Li Jia,Wan Ma et al.
Jiahui Li et al.
Iron exerts significant influences on glucose metabolism. However, the regulatory mechanisms underlying disordered glucose response remains largely unclear. The aim of this study was to examine the impact of dietary iron on hepatic gluconeo...
Pectin supplementation ameliorates intestinal epithelial barrier function damage by modulating intestinal microbiota in lipopolysaccharide-challenged piglets [0.03%]
果胶通过调控脂多糖刺激仔猪肠道菌群改善肠道屏障功能损伤
Xiaobin Wen,Ruqing Zhong,Guoqi Dang et al.
Xiaobin Wen et al.
During weaning, infants and young animals are susceptible to severe enteric infections, thus inducing intestinal microbiota dysbiosis, intestinal inflammation, and impaired intestinal barrier function. Pectin (PEC), a prebiotic polysacchari...