Shikimic acid ameliorates immobilization-induced muscle atrophy through regulation of inflammation and muscle protein homeostasis [0.03%]
虾夷素改善束缚致肌肉萎缩的机制研究
Mi-Bo Kim,Jihee Yoo,Chae Young Moon et al.
Mi-Bo Kim et al.
Immobilization induces skeletal muscle atrophy by disrupting muscle protein homeostasis, leading to progressive loss of muscle mass and function. Shikimic acid (SA), a plant-derived organic acid with anti-inflammatory and antioxidant proper...
Interaction between Composite Dietary Antioxidant Index and physical activity on sleep condition: NHANES 2007-2018 [0.03%]
复合膳食抗氧化指数与身体活动对睡眠状况的交互作用：基于NHANES 2007-2018数据的研究
Yan Liu,Xiaopeng Sun,Yu Han et al.
Yan Liu et al.
Background: The Composite Dietary Antioxidant Index (CDAI), a composite score of multiple dietary antioxidants that assesses and reflects the overall impact of dietary antioxidants on health. The state of sleep is one of ...
LncRNA RRP12-AS regulates UCP1-mediated lipid metabolism through hnRNPA1 and the identification of a functionally conserved human homolog [0.03%]
长链非编码RNA RRP12-AS通过hnRNPA1调节UCP1介导的脂质代谢并鉴定其功能保守的人同源基因
Guoze Wang,Yi Wang,Jiaqiang Luo et al.
Guoze Wang et al.
Long non-coding RNAs (lncRNAs) are important regulators of adipogenesis and energy metabolism, but their roles in visceral fat deposition remain incompletely understood. Here, we investigated the function of the rabbit lncRNA RRP12-AS and e...
The Emerging Role of microRNAs as Targets of Phytochemical Intervention in Myocardial Infarction: A Systematic Review of In Vitro and In Vivo Studies [0.03%]
植物化学干预心肌梗死的微小RNA作用机制及研究进展：体内外研究系统性综述
Mirko Marino,Benedetta Mercuriali,Laura Castiglioni et al.
Mirko Marino et al.
This systematic review evaluates the current literature on the protective mechanisms of dietary phytochemicals in cellular and animal models of myocardial infarction, with a specific focus on miRNA modulation. A literature search was conduc...
The high-carbohydrate diet delayed skin wound healing through suppressing AGEs-MTOR-HIF1A-driven glycolysis in turbot, Scophthalmus maximus L [0.03%]
高碳水化合物日粮通过抑制AGEs-MTOR-HIF1A驱动的糖酵解延迟欧洲扁鱼皮肤伤口愈合
Zhichu Chen,Yuanting Li,Yuanyuan Fang et al.
Zhichu Chen et al.
This study investigated the impact of a high-carbohydrate diet (HC: 25% carbohydrate) on skin wound healing in turbot versus a control diet (CC: 16% carbohydrate). Following 10 weeks of triple replicates of fish (n = 40), standardized 8 mm ...
L-serine dose-dependently ameliorates high-selenium-induced insulin resistance in mice [0.03%]
L-丝氨酸剂量依赖性缓解小鼠高硒诱导的胰岛素抵抗
Shuo Zhan,Qin Wang,Yiqun Liu et al.
Shuo Zhan et al.
Background: Supranutritional selenium intake, while potentially oncoprotective, paradoxically elevates the risk of type 2 diabetes through metabolic hijacking of the one-carbon pool. Se-detoxification exhausts S-adenosylm...
Adaptive response of breastmilk metabotype and miRNAs patterns in a rat model of gestational diabetes and its postpartum evolution [0.03%]
妊娠糖尿病大鼠模型下乳汁代谢型和miRNA的适应性变化及其产后演变规律研究
Paul Bobin,Sandrine Le Guillou,Mathilde Gourdel et al.
Paul Bobin et al.
Background: Epidemiological evidence suggests foetal-hyperglycemia predisposes the offspring of mothers with gestational diabetes (GDM) to insulin resistance. While breastfeeding is known to improve metabolic outcomes in ...
Ferulic Acid Ameliorates High-Fat Diet-Induced Hyperlipidemia in Mice via Suppressing the PGC-1β/miR-378a-3p Axis [0.03%]
金丝桃素通过抑制PGC-1β/miR-378a-3p轴改善高脂饮食诱导的小鼠高脂血症
Kaili Cui,Meihong Chen,Lichao Zhang et al.
Kaili Cui et al.
Hyperlipidemia (HLP) has emerged as a prevalent chronic metabolic disorder and seriously threatens human health. Given the limitations of current pharmacotherapies, the exploration of safe and effective natural bioactive compounds for HLP m...
Quercetin Reverses DEHP-Induced ZBP1-Mediated PANoptosis in Thymus by Targeting NF-κB to Regulate the TNF-α/ROS Signaling Pathway [0.03%]
槲皮素通过靶向NF-κB调节TNF-α/ROS信号通路逆转DEHP诱导的胸腺ZBP1介导的PANoptosis
Yuting Dong,Xiaodan Wang,Shize Wang et al.
Yuting Dong et al.
Quercetin (Que), a natural dietary flavonoid, possesses significant antioxidative and immunoregulatory properties. Di(2-ethylhexyl) phthalate (DEHP), a pervasive environmental endocrine-disrupting chemical, triggers oxidative stress (OS) an...
Molecular Pathways and Clinical Applications of Probiotics as Effective Supporters of Intestinal, Neurologic, and Cardiovascular Health: a Narrative Review [0.03%]
益生菌分子机制及其在肠道、神经和心血管健康支持方面的临床应用：综述
Álvaro Vergara A Nieto,Andrés Halabi Diaz,Millaray Hernández Millán et al.
Álvaro Vergara A Nieto et al.
Purpose of review: This narrative review aims to synthesize current knowledge on the molecular mechanisms and clinical applications of probiotics across three major health domains: intestinal, neurologic, and cardiovascul...