Transcriptional analysis of glial cell differentiation in the postnatal murine spinal cord [0.03%]
小鼠出生后脊髓中神经胶质细胞分化过程的转录组分析
Barbara B Raddatz,Annika Lehmbecker,Arno Kalkuhl et al.
Barbara B Raddatz et al.
Postnatal murine spinal cord represents a good model system to study mammalian central nervous system myelination in vivo as a basis for further studies in demyelinating diseases. Transcriptional changes were analyzed in SJL/J mice on postn...
Cerebral blood volume measurement using near-infrared time-resolved spectroscopy and histopathological evaluation after hypoxic-ischemic insult in newborn piglets [0.03%]
新生猪lets低氧缺血损伤后近红外时域光谱 cerebral blood volume 测定及组织病理学评价
Makoto Nakamura,Wataru Jinnai,Satoshi Hamano et al.
Makoto Nakamura et al.
The aim of this study was to assess the relationship between the cerebral blood volume (CBV) measured by near-infrared time-resolved spectroscopy (TRS) and pathological change of the brain in a hypoxic-ischemic (HI) piglet model. Twenty-one...
Fragile X mental retardation protein (FMRP) interacting proteins exhibit different expression patterns during development [0.03%]
弗里盖尔X综合症蛋白(FMRP)相互作用的蛋白质在发育过程中表现出不同的表达模式
C M Bonaccorso,M Spatuzza,B Di Marco et al.
C M Bonaccorso et al.
Fragile X syndrome is caused by the lack of expression of fragile X mental retardation protein (FMRP), an RNA-binding protein involved in mRNA transport and translation. FMRP is a component of mRNA ribonucleoprotein complexes and it can int...
Urinary biomarkers of oxidative damage in Maple syrup urine disease: the L-carnitine role [0.03%]
L-肉毒碱在枫糖尿病氧化损伤尿液生物标志物中的作用
Gilian Guerreiro,Caroline Paula Mescka,Angela Sitta et al.
Gilian Guerreiro et al.
Maple syrup urine disease (MSUD) is a disorder of branched-chain amino acids (BCAA). The defect in the branched-chain α-keto acid dehydrogenase complex activity leads to an accumulation of these compounds and their corresponding α-keto-ac...
A reliable and valid method for manual demarcation of hippocampal head, body, and tail [0.03%]
一种可靠有效的人工划分海马头部、体部和尾部的方法
Ana M Daugherty,Qijing Yu,Robert Flinn et al.
Ana M Daugherty et al.
There is a growing interest in characterizing functional specialization along the long axis of the hippocampus in humans. Variability in volumetry along the long axis of the hippocampus may be of functional relevance in human development, a...
High plasma neopterin levels in Chinese children with autism spectrum disorders [0.03%]
自闭症谱系障碍患儿血浆中新蝶呤水平升高
Hong-xiang Zhao,Sha-sha Yin,Jin-gang Fan
Hong-xiang Zhao
Background: Neopterin, a pteridine mainly synthesized by activated macrophages, is a marker of inflammation, immune system activation and an active participant in Autism spectrum disorders (ASD). The aim of this study was...
Signaling via the transcriptionally regulated activin receptor 2B is a novel mediator of neuronal cell death during chicken ciliary ganglion development [0.03%]
转录调节的活化素受体2B介导的感觉神经元程序性细胞死亡是鸡睫状神经节发育过程中的新信号通路
S Koszinowski,K Buss,K Kaehlcke et al.
S Koszinowski et al.
The TGF-β ligand superfamily members activin A and BMP control important aspects of embryonic neuronal development and differentiation. Both are known to bind to activin receptor subtypes IIA (ActRIIA) and IIB, while in the avian ciliary g...
Reduced density of dendritic spines in pyramidal neurons of rats exposed to alcohol during early postnatal life [0.03%]
酒精暴露影响的大鼠海马锥体神经元树突棘密度的降低效应
Andrea De Giorgio,Alberto Granato
Andrea De Giorgio
Dendritic spines are the main postsynaptic sites of excitatory connections of neocortical pyramidal neurons. Alterations of spine shape, number, and density can be observed in different mental diseases, including those caused by development...
Sexual differences in long-term effects of prenatal chronic mild stress on anxiety-like behavior and stress-induced regional glutamate receptor expression in rat offspring [0.03%]
慢性轻度应激对子代长期焦虑行为表型及应激诱导的区域谷氨酸受体表达的影响性别差异研究
Yan Wang,Yuchao Ma,Wenwen Cheng et al.
Yan Wang et al.
Severe adverse life events during pregnancy may increase the risk of anxiety disorders in the offspring. Glutamate receptors are neurobiological targets in anxiety disorders. In this study, we investigated the effects of prenatal chronic mi...
Cerebrovascular adaptations to chronic hypoxia in the growth restricted lamb [0.03%]
生长受限羔羊慢性缺氧下的脑血管适应性变化
Margie Castillo-Melendez,Tamara Yawno,Beth J Allison et al.
Margie Castillo-Melendez et al.
Chronic moderate hypoxia induces angiogenic adaptation in the brain, reflecting a modulatory role for oxygen in determining cerebrovascular development. Chronic intrauterine fetal hypoxia, such as occurs in intrauterine growth restriction (...