A Novel De Novo Frameshift Variant of TBL1XR1 Leads to Neurodevelopmental Disorders and Treatment Experience [0.03%]
TBL1XR1的新发 frameshift变异导致神经发育障碍及治疗经验
Fangfang Cao,Jihua Xie,Zhixin Huang et al.
Fangfang Cao et al.
Background: Neurodevelopmental disorders were a wide range of cognitive and behavioural disorders. Its pathogenic genes, transduction beta like 1 X-linked receptor 1 (TBL1XR1), had been a hot research topic recently. Howe...
Gender-Specific Behavioural and Nociceptive Alterations in an Autism Model Induced by Prenatal Exposure to Lipopolysaccharide [0.03%]
产前暴露于脂多糖诱导的自闭症模型中性别特异的行为和痛觉异常反应
Elizabeth Teodorov,Rodrigo Augusto Foganholi da Silva,Maria Martha Bernardi et al.
Elizabeth Teodorov et al.
Autism spectrum disorders (ASD) are frequently associated with sensory abnormalities, particularly altered pain sensitivity, which may manifest as either hypo- or hypersensitivity to painful stimuli. Despite the higher prevalence of ASD in ...
Effects of Pregestational Stress and Concomitant Administration of Dracocephalum moldavica Extract on Seizure Behaviours in Next Generation Developing Rats [0.03%]
孕前应激及伴予毛地黄鼠带提取物对后代大鼠发育中癫痫行为的影响
Hajar Ramezanikhah,Leila Ghassemifard,Ehsan Saboory et al.
Hajar Ramezanikhah et al.
Objective: Little is known about how the effects of pregestational stress on seizure susceptibility in male and female offspring might be attenuated. The current study was undertaken to determine whether Dracocephalum mol...
Narcissistic Traits, Self-Esteem and Aggression Symptoms in Children and Adolescents With Attention-Deficit/Hyperactivity Disorder [0.03%]
narcissism、自我评价和注意缺陷多动障碍青少年的症状表現
Gökçe Kırlı Öcal,Arif Önder,Aslı Sürer Adanır et al.
Gökçe Kırlı Öcal et al.
Although it is well established that many children diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD) experience considerable difficulties during the transition to adolescence, the specific pathways linking childhood ADHD to agg...
Microplastics as a Silent Threat to Child Neurodevelopment: Evidence and Perspectives on Autism [0.03%]
微塑料对儿童神经发育的隐秘威胁：自闭症的研究证据与展望
David Santos Grillo,Maria Eduarda de Carvalho Alencar,Vanessa da Silva Ribeiro Souza et al.
David Santos Grillo et al.
Autism spectrum disorder (ASD) is caused by an interaction of both environment and genetics. Recently, there has been an increased focus on how environmental toxins may alter a child's biological systems. Microplastics and nanoplastics are ...
Homozygous Variant in NADSYN1 Causes Multiple Congenital Vertebral Malformation, With Neurodevelopmental Disorder [0.03%]
NADSYN1同功变异导致多发性先天性脊椎畸形并神经发育障碍
Zaheer Ahmed,Summan Thahiem,Allah Bakhsh et al.
Zaheer Ahmed et al.
Congenital NAD deficiency (CNDD) is a rare autosomal recessive disorder characterized by multiple congenital anomalies, frequently affecting the spine, kidneys, heart and nervous system. NADSYN1 is one of the genes of the NAD pathway that i...
Redefining Peer Tutoring: Academic and Social Gains Through Twice-Exceptional Student Leadership [0.03%]
通过双例外才学生领导力实现学术和社会进步的同伴辅导再定义
Gul Kahveci
Gul Kahveci
This study explored the dual effects-both academic and social-of a peer tutoring framework where a twice-exceptional student with autism spectrum disorder (2e-ASD) served as a tutor for three students with learning disabilities (LDs). The g...
Personalized Medicine in Autism Spectrum Disorder: Integrating Epigenomics, Microbiome Research and Early Diagnostics [0.03%]
自闭症谱系障碍的精准医疗：表观遗传学、微生物组研究和早期诊断的整合
Amr Ali Mohamed Abdelgawwad El Sehrawy,Omar I Aljumaili,Ulugbek Axmedov et al.
Amr Ali Mohamed Abdelgawwad El Sehrawy et al.
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition characterized by persistent difficulties in social communication together with restricted, repetitive patterns of behaviour and sensory-processing differences. G...
Complicated Spastic Paraparesis: Study of a Patient With a De Novo Pathogenic Variant in ELOVL1 [0.03%]
复杂性痉挛性轻偏瘫：ELOVL1基因新发致病突变病例研究
Ylenia Vaia,Eleonora Mura,Fabio Bruschi et al.
Ylenia Vaia et al.
Very long-chain fatty acid elongase-1 (ELOVL1) is essential for fatty acid elongation and is widely expressed in numerous tissues, including the central nervous system, being involved in the elongation of very long-chain fatty acids (VLCFAs...
Sleep Disturbances and Behavioural Phenotypes in Children With Autism Spectrum Disorder: A Comparative Study With Typically Developing Peers [0.03%]
孤独症谱系障碍儿童睡眠问题及行为表型与普通发展匹配儿羣的比较研究
Doga Sevincok,Cansu Mercan Isik,Mutlu Muhammed Ozbek et al.
Doga Sevincok et al.
Objectives: The primary objective of this study was to investigate the relationship between different types of sleep problems and specific behavioural difficulties in children and adolescents with autism spectrum disorder...