Antenatal betamethasone produces protracted changes in anxiety-like behaviors and in the expression of microtubule-associated protein 2, brain-derived neurotrophic factor and the tyrosine kinase B receptor in the rat cerebellar cortex [0.03%]
孕酮贝特米塞松产生长期的类似焦虑的行为变化，并在大鼠小脑皮层中微管相关蛋白2、脑源性神经营养因子和酪氨酸激酶B受体表达的变化
Rodrigo Pascual,Martina Valencia,Carlos Bustamante
Rodrigo Pascual
Using classic Golgi staining methods, we previously showed that the administration of synthetic glucocorticoid betamethasone in equivalent doses to those given in cases of human premature birth generates long-term alterations in Purkinje ce...
Maternal omega-3 fatty acid supplementation to a vitamin B12 deficient diet normalizes angiogenic markers in the pup brain at birth [0.03%]
维生素B12缺乏 diet补充母体欧米茄-3脂肪酸可正常化新生儿大脑的血管生成标志物
Richa S Rathod,Amrita A Khaire,Anvita A Kale et al.
Richa S Rathod et al.
Vitamin B12 and omega-3 fatty acids are critical for normal brain development and function and their deficiencies during pregnancy could have adverse effects on cognitive performance in children. Our earlier studies indicate that both mater...
Prenatal undernutrition increases the febrile response to lipopolysaccharides in adulthood in male rats [0.03%]
孕期营养不良增强雄性大鼠成年后对内毒素的发热反应
Takeshi Iwasa,Toshiya Matsuzaki,Altankhuu Tungalagsuvd et al.
Takeshi Iwasa et al.
It has been reported that prenatal undernutrition affects the development of the peripheral immune system. In this study, the effects of prenatal undernutrition on the febrile response and hypothalamic innate immune system were evaluated in...
Autistic spectrum disorders: A review of clinical features, theories and diagnosis [0.03%]
自闭症谱系障碍的临床特征、理论和诊断综述
Marc Fakhoury
Marc Fakhoury
Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders that is among the most severe in terms of prevalence, morbidity and impact to the society. It is characterized by complex behavioral phenotype and deficits in both soci...
LH and testosterone production are more sensitive to the suppressive effects of food deprivation in prenatally undernourished male rats [0.03%]
prenatal营养不良影响雄性大鼠对食物剥夺的反应
Takeshi Iwasa,Toshiya Matsuzaki,Altankhuu Tungalagsuvd et al.
Takeshi Iwasa et al.
Although prenatal undernutrition affects the development of metabolic, physiological, and reproductive functions, it remains unclear whether it also affects physiological responses to undernutrition in adulthood. Therefore, in this study we...
The effects of PBDE-209 exposure during pregnancy on placental ET-1 and eNOS expression and the birth weight of offspring [0.03%]
妊娠期暴露于多溴二苯醚-209对胎盘内ET-1和eNOS表达及子代体重的影响效应研究
Peili Du,Zhihua Li,Lili Du et al.
Peili Du et al.
Decabrominated diphenyl ether (PBDE-209) is a persistent organic pollutant. Gestational exposure to PBDE-209 can accumulate in pregnant women and fetuses via the placenta and umbilical cord, affecting perinatal outcome. In this study, pregn...
Hypoxic preconditioning can reduce injury-induced inflammatory processes in the neonatal rat brain [0.03%]
缺氧预处理可减少伤害性刺激诱导的新生鼠脑炎性反应
Jasneet Parmar,Nicole M Jones
Jasneet Parmar
Inflammation plays an important role in the pathophysiology of neonatal hypoxic-ischemic (HI) brain injury. Studies have shown that hypoxic preconditioning (HP) can ameliorate brain damage, but its effects on inflammation remain unknown. Po...
Advanced magnetic resonance spectroscopy and imaging techniques applied to brain development and animal models of perinatal injury [0.03%]
应用于脑发育和围产期损伤动物模型的高级磁共振波谱及影像学技术
Yohan van de Looij,Justin M Dean,Alistair J Gunn et al.
Yohan van de Looij et al.
Magnetic resonance spectroscopy (MRS) and magnetic resonance imaging (MRI) are widely used in the field of brain development and perinatal brain injury. Due to technical progress the magnetic field strength (B0) of MR systems has continuous...
Effects of developmental alcohol exposure vs. intubation stress on BDNF and TrkB expression in the hippocampus and frontal cortex of neonatal rats [0.03%]
酒精和插管应激对新生大鼠海马及前额叶脑源性神经营养因子及其受体表达的影响
K E Boschen,K J Criss,V Palamarchouk et al.
K E Boschen et al.
Third trimester-equivalent alcohol exposure causes significant deficits in hippocampal and cortical neuroplasticity, resulting in alterations to dendritic arborization, hippocampal adult neurogenesis, and performance on learning tasks. The ...
Expression of vascular endothelial growth factor (VEGF) mRNA, VEGF receptor 2 (Flk-1) mRNA, and of VEGF co-receptor neuropilin (Nrp)-1 mRNA in brain tissue of aging Tg2576 mice by in situ hybridization [0.03%]
AGE-TG2576小鼠脑组织中血管内皮生长因子及其受体mRNA的原位杂交检测研究
Abebe Muche,Marina Bigl,Thomas Arendt et al.
Abebe Muche et al.
Vascular endothelial growth factor (VEGF) has been characterized as a heparin binding angiogenic growth factor displaying high specificity for endothelial cells. It is profoundly accumulated and co-localized with amyloid beta (Aβ) plaques ...