CASPR2-Deficiency Neurodevelopmental Disorder Associated With Biallelic CNTNAP2 Gene Variants: Phenotypic and Genetic Analysis From Prenatal to Paediatric Period [0.03%]
与双等位基因CNTNAP2基因变异相关的CASPR2缺陷神经发育障碍：从产前到儿科的表型和遗传分析
Shouxing Wang,Yuanzhi He,Zhongli Zhao et al.
Shouxing Wang et al.
Variants of the CNTNAP2 gene are closely associated with various neurological disorders, including neurodevelopmental disorders, schizophrenia and behavioural abnormalities. Biallelic CNTNAP2 gene variants may lead to more complex or severe...
Differential Functional Connectivity Between Silent Reading and Resting-State fMRI and Their Relationships With Reading Performance in Children With and Without Dyslexia [0.03%]
儿童阅读困难症患者与非患者静息态功能磁共振和阅读时的功能连接差异及其与阅读成绩的关系研究
Şerife Gengeç Benli,Esra Demirci,Semra İçer et al.
Şerife Gengeç Benli et al.
The clinical diagnostic parameters of dyslexia and the alterations it creates on brain connectivity continue to be the focus of current studies. In this study, where clinical neuropsychiatric tests and neuroimaging results are examined toge...
Adolescent Chronic Sleep Disruption Increases Blood-Brain Barrier Permeability, but in a Time-, Region- and Sex-Dependent Manner in CD-1 Mice [0.03%]
青春期慢性睡眠紊乱会以时间、区域和性别依赖性方式增加CD-1小鼠血脑屏障通透性
Abigale Hinterberger,Pasquale Esposito,Luna Cappelletti et al.
Abigale Hinterberger et al.
During puberty and adolescence, there is a natural change in the circadian rhythm, which could result in inadequate sleep and increase the likelihood of physical and mental health issues. Previously, we have developed a mouse model showing ...
Neuroprotective Effect of Palmatine Against Anti-Epileptic Drug Induced Autism in Wistar Rat Pups [0.03%]
palmatine对西大鼠抗癫痫药物所致自闭症的神经保护作用
Kulwant Singh,Dinesh Dhingra
Kulwant Singh
Background: Autism spectrum disorder is a developmental disorder that affects the central nervous system. It is characterized by impaired social interaction and communication, along with patterns of repetitive behaviours....
Novel KDM3B Variants in Two Chinese Patients With Global Developmental Delay and Autism [0.03%]
KDM3B新变异导致的中国患儿发育迟缓和自闭症谱系障碍病例报告
Fangfang Cao,Ling Xiong,Huaping Wu et al.
Fangfang Cao et al.
Background: Haploinsufficiency of KDM3B has also been linked to developmental delay, intellectual disability, autism spectrum disorder (ASD) and immunodeficiency known as developmental delay, intellectual disability, join...
Deficiency of the Tangier Disease Gene Abca1 Is Associated With Microglial Defects in Mice [0.03%]
与Tangier病基因ABCA1缺乏相关的的小鼠微胶质缺陷现象
Tomas Celis,Oriana Ramírez-Herrera,Myrna Barraza et al.
Tomas Celis et al.
Microglia, the resident macrophages of the central nervous system, are a diverse population that develop during embryonic and postnatal stages in the mouse. Several signalling pathways are involved in their specification and maturation, but...
Sericin Administration During Gestation Improves Reflexive Motor Behaviour and Serum Growth Hormone and IGF Levels in Mice Offspring [0.03%]
丝素蛋白在妊娠期间的施用可改善小鼠后代的反射运动行为以及血清生长激素和IGF水平
Shahla Fadaei,Shahin Hassanpour,Akram Eidi et al.
Shahla Fadaei et al.
This study investigated the effect of sericin consumption during gestation on the neurodevelopmental reflexes, motor behaviour and biochemical profiles of mice offspring. Forty pregnant NMRI mice were randomly assigned into four groups: a c...
Low Expression Levels of MAOA and TPH1 Genes May Represent Risk Factors in Boys With Autism Spectrum Disorder-A Case-Control Study [0.03%]
MAOA和TPH1基因低表达水平可能是自闭症谱系障碍男童的风险因素-一项病例对照研究
Hilal Akalin,Berrin Bilgic,Sibelnur Avcil et al.
Hilal Akalin et al.
Introduction: It has been reported that disruptions in the metabolic pathways of tryptophan, the precursor of the neurotransmitter serotonin, may contribute to the development of autism spectrum disorder (ASD); however, f...
Madhusmita Mishra,Bibhukalyan P Nayak
Madhusmita Mishra
Zebrafish (Danio rerio) have emerged as a pivotal model organism in translational neuroscience, neuropharmacology and CNS disorder research, leveraging their striking anatomical and physiological parallels to humans. With a brain architectu...
Catalase Gene Variants and Oxidative Stress in Autism Spectrum Disorder: A Northern Lebanon Cohort and Aripiprazole In Vitro Toxicity [0.03%]
过氧化氢酶基因变异和自闭症谱系障碍中的氧化应激：来自黎巴嫩北部人群队列和阿立哌唑体外毒性结果的证据
Jeanne d&#x;arc Bacha,Nawal El Zoebi,Houssein Al-Attrache
Jeanne d&#x;arc Bacha
Background: Autism spectrum disorder (ASD) is a multifactorial neurodevelopmental condition influenced by genetic, epigenetic and environmental factors. Oxidative stress and antioxidant enzyme polymorphisms, particularly ...