Armanda Teixeira-Gomes,Vera Marisa Costa,Rita Feio-Azevedo et al.
Armanda Teixeira-Gomes et al.
Amphetamine-type psychostimulants (ATS), such as amphetamine (AMPH), 3,4-methylenedioxymethamphetamine (MDMA), and methamphetamine (METH) are psychoactive substances widely abused, due to their powerful central nervous system (CNS) stimulat...
Immediate and long-term effects of psychological stress during adolescence in cardiovascular function: comparison of homotypic vs heterotypic stress regimens [0.03%]
青少年心理压力对心血管功能的即时和长期影响：同质性与异质性压力方案的比较
Josiane O Duarte,Cleopatra S Planeta,Carlos C Crestani
Josiane O Duarte
Adolescence has been proposed as an ontogenic period of vulnerability to stress. Nevertheless, the impact of stressful events during adolescence in cardiovascular activity is poorly understood. Therefore, the purpose of this study was to in...
Evaluation of spontaneous dense array gamma oscillatory activity and minor physical anomalies as a composite neurodevelopmental endophenotype in schizophrenia [0.03%]
评估自发密集阵列γ振荡活动和轻微身体畸形作为精神分裂症的复合神经发育内表型的价值
Sai Krishna Tikka,S Haque Nizamie,Nishant Goyal et al.
Sai Krishna Tikka et al.
Objective: Minor physical anomalies (MPAs) and gamma oscillatory activity have been proposed as associated endophenotypes in schizophrenia. Combining these endophenotypes to create a composite endophenotype may help ident...
Increased expression of Hes5 protein in Notch signaling pathway in the hippocampus of mice offspring of dams fed a high-fat diet during pregnancy and suckling [0.03%]
高脂饮食母鼠后代海马区Notch信号通路Hes5蛋白表达增强
Cristiano Mendes-da-Silva,Simone Ferreira Lemes,Tanyara da Silva Baliani et al.
Cristiano Mendes-da-Silva et al.
Maternal high-fat diet (HFD) impairs hippocampal development of offspring promoting decreased proliferation of neural progenitors, in neuronal differentiation, in dendritic spine density and synaptic plasticity reducing neurogenic capacity....
Cerebellum neurotransmission during postnatal development: [Pt(O,O'-acac)(γ-acac)(DMS)] vs cisplatin and neurotoxicity [0.03%]
小儿后天发育期间小脑神经信号传输：[Pt(O,O'-acac)(γ-acac)(DMS)]和顺铂及神经毒素作用关系的研究
Valeria Maria Piccolini,Alessandra Esposito,Veronica Dal Bo et al.
Valeria Maria Piccolini et al.
Several chemotherapeutic drugs are known to cause neurotoxicity. Platinum-based agents in use or in clinical trials display neurotoxic potential accompanied by neurological complications; recent studies have identified a large number of beh...
Variations in the neonatal environment modulate adult behavioral and brain responses to palatable food withdrawal in adult female rats [0.03%]
新生环境的改变调节了成年雌性大鼠对美味食物撤除的成年行为和大脑反应
Juliana Barcellos Colman,Daniela Pereira Laureano,Tatiane Madeira Reis et al.
Juliana Barcellos Colman et al.
Background/objectives: Early handling alters adult behavioral responses to palatable food and to its withdrawal following a period of chronic exposure. However, the central mechanisms involved in this phenomenon are not k...
Assessment of in-utero venlafaxine induced, ROS-mediated, apoptotic neurodegeneration in fetal neocortex and neurobehavioral sequelae in rat offspring [0.03%]
评估盐酸文拉法辛致胎鼠海马ROS介导的凋亡性神经退行性病变及子代大鼠的行为异常
Manish Singh,K P Singh,Shubha Shukla et al.
Manish Singh et al.
Venlafaxine (VEN), a serotonin and noradrenaline reuptake inhibitor is being used as a drug of choice for treating clinical depression even during pregnancy. It is an important therapeutic option in the treatment of perinatal depression, bu...
IL-1β increases necrotic neuronal cell death in the developing rat hippocampus after status epilepticus by activating type I IL-1 receptor (IL-1RI) [0.03%]
IL-1β通过激活I型IL-1受体(IL-1RI)增加宫内炎症后海马区坏死性神经元细胞死亡
Jesús-Servando Medel-Matus,Dulce-Mariely Álvarez-Croda,Joel Martínez-Quiroz et al.
Jesús-Servando Medel-Matus et al.
Interleukin-1β (IL-1β) is associated with seizure-induced neuronal cell death in the adult brain. The contribution of IL-1β to neuronal injury induced by status epilepticus (SE) in the immature brain remains unclear. In the present study...
Developmental changes in hypothalamic toll-like-receptor 4 mRNA expression and the effects of lipopolysaccharide on such changes in female rats [0.03%]
雌性大鼠下丘脑Toll样受体4的发育变化及其对内毒素感染易感性影响的研究
Takeshi Iwasa,Toshiya Matsuzaki,Altankhuu Tungalagsuvd et al.
Takeshi Iwasa et al.
Hypothalamic pro-inflammatory cytokine expression exhibits a weaker response to lipopolysaccharides (LPS) during the early neonatal period than during the later developmental period. Although toll-like receptor 4 (TLR4), which recognizes ba...
Embryological exposure to valproic acid disrupts morphology of the deep cerebellar nuclei in a sexually dimorphic way [0.03%]
胚胎暴露于丙戊酸盐会以性别二态的方式破坏深 cerebellar 核的形态
Todd M Mowery,Sarah M Wilson,Polina V Kostylev et al.
Todd M Mowery et al.
Autism spectrum disorders (ASD) is diagnosed in males at a much higher rate than females. For this reason, the majority of autism research has used male subjects exclusively. However; more recent studies using genetic sex as a factor find t...