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Macrophage membrane-decorated MnO2 nanozyme catalyzed the scavenging of estradiol for endometriosis treatment [0.03%] 用于治疗子宫内膜异位症的雌二醇纳米酶催化清除调控
Qinkun Sun,Jiahao Chen,Mengjie Yang et al. Qinkun Sun et al.
Endometriosis (EMs) is an inflammatory, estrogen-dependent disease characterized by the growth of endometrial-like tissue outside the uterus. Despite many efforts to develop effective treatment regimens, the overall response to halting EMs ...
Propelling CuCo-based nanozyme design to new heights through triple enzyme-like power for high-efficiency bacterial eradication [0.03%] 通过三重酶促活性推动CuCo基纳米酶设计高效杀菌性能研究
Zheng Liu,Ruibang Wu,Yulin Jiang et al. Zheng Liu et al.
Bacterial infection-related diseases are a serious issue that threatens human health, and it is highly desirable to develop a high-performance antibacterial agent to combat it. Herein, copper/cobalt-based metal sulfide nanoparticles (CCS NP...
Fe-Ni dual-single atoms nanozyme with high peroxidase-like activity for sensitive colorimetric and fluorometric dual-mode detection of cholesterol [0.03%] 一种用于检测胆固醇的高类过氧化物酶活性的Fe-Ni双单原子纳米酶及色度和荧光双模式检测方法
Jia-Qi Li,Yan-Wen Mao,Rui Zhang et al. Jia-Qi Li et al.
Cholesterol is widely existed in nerve myelin sheath and various membrane structures, whose abnormal level would deteriorate human cells or even cause diseases. Herein, Fe-Ni dual-single-atom nanozyme was efficiently incorporated into N-dop...
ATP-triggered, selective superoxide radical generating oxidase-mimetic cerium oxide nanozyme exhibiting efficient antibacterial activity at physiological pH [0.03%] 一种高效抗菌的CeO₂纳米酶：生理pH条件下选择性生成超氧根自由基的氧化酶模拟物
Divya Mehta,Paresh Sharma,Sanjay Singh Divya Mehta
Bacterial infections are considered as one of the major health threats to the global population. The advent of bacterial species with antibiotic resistance has attracted significant efforts to develop novel materials and strategies to effec...
Surface-modified cerium dioxide nanoparticles with improved anti-amyloid and preserved nanozymatic activity [0.03%] 具有改善的抗淀粉样蛋白和保留的纳米酶活性的改性氧化铈纳米粒子
Ivana Garcarova,Eva Valusova,Yuliia Shlapa et al. Ivana Garcarova et al.
Cerium dioxide nanoparticles (CeO2 NPs) are used increasingly in nanotechnology and particularly in biotechnology and bioresearch. Thus, CeO2 NPs have been successfully tested in vitro as a potential therapeutic agent for various pathologie...
Self-cascade catalytic single-atom nanozyme for enhanced breast cancer low-dose radiotherapy [0.03%] 自我催化单原子纳米酶用于增强乳腺癌低剂量放射治疗
Pengyuan Qi,Cheng Luo,You Pan et al. Pengyuan Qi et al.
Radiotherapy (RT) efficacy can be promoted with the help of nanoenzyme that can "re-programing" the tumour's micro-environment by changing the expression level of special bio-molecules. However, problems such as low reaction efficiency, lim...
MOF-based nanozyme grafted with cooperative Pt(IV) prodrug for synergistic anticancer therapy [0.03%] 基于协同Pt(IV)前药的金属有机骨架纳米酶的合成用于协同抗肿瘤治疗
Ping-Hsuan Wu,Pei-Fen Cheng,Watchareeya Kaveevivitchai et al. Ping-Hsuan Wu et al.
Manipulating Fenton chemistry in tumor microenvironment (TME) for the generation of reactive oxygen species is an effective strategy for chemodynamic therapy. However, this is usually restricted by limited intracellular content of H2O2 and ...
Nanozymes and nanoflower: Physiochemical properties, mechanism and biomedical applications [0.03%] 纳米酶和纳米花：理化性质、机制及生物医学应用
Mohammad Perwez,Sie Yon Lau,Danish Hussain et al. Mohammad Perwez et al.
Natural enzymes possess several drawbacks which limits their application in industries, wastewater remediation and biomedical field. Therefore, in recent years researchers have developed enzyme mimicking nanomaterials and enzymatic hybrid n...
High aspect ratio plasmonic Au/Ag nanorods-mediated NIR-II photothermally enhanced nanozyme catalytic cancer therapy [0.03%] 高宽比等离激元金/银纳米棒介导的近红外Ⅱ区光热增强型纳米酶催化癌症治疗
Xinyu Cui,Minghui Li,Lei Tong et al. Xinyu Cui et al.
Chemodynamic therapy (CDT) is based on the endogenous generation of cytotoxic hydroxyl free radicals (·OH) with high specificity and selectivity between cancer and normal cells. However, its efficacy is often limited by the relatively defi...
Mesoporous carbon nanoenzyme as nano-booster for photothermal-enhanced photodynamic therapy compared with graphene oxide [0.03%] 中孔碳纳米酶作为光热增强光动力治疗的纳米增效剂与氧化石墨烯的对比研究
Shuaipeng Feng,Jiahong Wang,Xiaoyang Mu et al. Shuaipeng Feng et al.
The over-expressed GSH in tumor microenvironment significantly weakens the lethal reactive oxygen species (ROS) generated by photodynamic therapy (PDT) and catalysis of nanoenzyme. Hence, it is necessary to excavate a versatile and effectiv...