Exploring the Interplay of PI3K/AKT/mTOR and JNK Signaling Pathways in Psoriasis: Insights from Systematic Review and Network Pharmacology Approach [0.03%]
探究PI3K/AKT/mTOR和JNK信号通路在银屑病中相互作用：系统综述与网络药理学方法新见解
Ali Ebrahimi,Pantea Mohammadi,Seyedeh Zahra Mirzaei et al.
Ali Ebrahimi et al.
Introduction: Psoriasis is a chronic inflammatory skin disease characterized by excessive keratinocyte proliferation, abnormal differentiation, and infiltration of inflammatory cells. Central to its pathogenesis are the P...
Mechanistic Insights into the Therapeutic Role of Curcumin in Leukemia: Molecular Targets and Clinical Implications [0.03%]
姜黄素治疗白血病的机制研究：分子靶点及临床意义
Rajan Logesh,Waqas Alam,Khalaf F Alsharif et al.
Rajan Logesh et al.
Leukemia is one of the most widespread and life-threatening malignancies that originates in the blood and bone marrow. Despite advances in treatment, there remains a need for safer and more effective therapeutic agents with fewer side effec...
The Contribution of Wearable Devices and Artificial Intelligence to Promoting Healthy Aging [0.03%]
可穿戴设备和人工智能在促进健康老龄化方面的贡献
Natarajan Sisubalan,Natarajan Vijay,Periyanaina Kesika et al.
Natarajan Sisubalan et al.
Introduction: Healthy aging involves consistently maximizing opportunities to maintain and enhance physical and mental well-being, fostering independence, and sustaining a high quality of life. This review examines recent...
Evaluating the Protective Immunity of 5'-Cap Altered Rabies mRNA Vaccines in a Mouse Model [0.03%]
评估5'-帽结构改变的狂犬病mRNA疫苗在小鼠模型中的保护性免疫效果
Teng Zhang,Wen Zhang
Teng Zhang
Introduction: Rabies Virus (RV or RABV) is a neurophilic pathogen predominantly transmitted to humans through bites, scratches, or wounds. Upon entering the central nervous system, the virus can cause severe symptoms, inc...
Pubescine as a Novel Antibacterial Agent Against Vancomycin-Resistant Enterococcus: Growth Inhibition, Antibiotic Synergy, and Anti-Biofilm Activity [0.03%]
披拂霉素作为抗万古霉素耐药肠球菌的新抗菌剂：抑菌生长、抗生素协同作用和抗生物膜活性
Raya Soltane
Raya Soltane
Introduction: The rise of Vancomycin-Resistant Enterococcus (VRE) has become a major public health concern due to its resistance to conventional antibiotics and ability to form biofilms. The urgent need for novel therapeu...
Detection of Virulence Factors and Antimicrobial Susceptibility among Clinical Strains of Enterococcus faecalis [0.03%]
粪肠球菌临床分离株的毒力因子检测及其对药物敏感性分析
Muhamad Ali K Shakhatreh,Hana Hamad Rabaiah,Omar F Khabour et al.
Muhamad Ali K Shakhatreh et al.
Introduction: Enterococci are common commensals in the gastrointestinal tract and are opportunistic organisms that can cause urinary tract infections, bacteremia, endocarditis, and pelvic infections. The study aimed to in...
PhytoCAT: A Comprehensive Data Repository of PhytoChemicals for Affordable Breast Cancer Therapeutics [0.03%]
基于植物化学物质的乳腺癌廉价治疗数据仓库PhytoCAT
Firdaus Fatima,Asgar Hussain Ansari,Surabhi Seth et al.
Firdaus Fatima et al.
Introduction: Breast cancer is a global health challenge with a high mortality rate of 30% of total cases in a year. Breast cancer presents in 4 main types, namely, TNBC, HER2+, luminal A, and Luminal B. Current treatment...
Essential Oils from Olea europaea and Cyperus esculentus Exhibit Promising Therapeutic Effect against Alzheimer's Disease in a Rat Model [0.03%]
Olea europaea和Cyperus esculentus中的精油可成为治疗阿尔茨海默病的潜在药物成分：基于大鼠模型的研究发现
Gamal M Hamad,Neven M Abdo,Sawsan A Abd Ellatif et al.
Gamal M Hamad et al.
Background: Alzheimer's disease poses a major challenge as a widespread and fatal neurodegenerative disorder, primarily affecting the elderly population worldwide. ...
Understanding Antimicrobial Resistance: From Mechanisms to Public Health Implications [0.03%]
抗菌药物耐药性的机制与公共卫生问题
Krishnendu Adhikary,Krishnendu Ganguly,Susmita Chakrabarty et al.
Krishnendu Adhikary et al.
Antimicrobial resistance (AMR) is a global public health crisis driven by the overuse and misuse of antibiotics, inadequate infection control practices, and the evolution of microbes. It compromises the effective treatment of infections, po...
The Role of Pioglitazone as a Ferroptosis Inhibitor in Mitigating Radiation-Induced Damage in Testicular Tissue of Mice [0.03%]
吡格列酮作为铁死亡抑制剂在减轻小鼠放射性睾丸组织损伤中的作用研究
Nikta Shabanian,Mohammad Shourmij,Zahra Nashtahosseini et al.
Nikta Shabanian et al.
Introduction: Radiation targets cancer but risks causing infertility by damaging sensitive testes, especially spermatogonia. This study investigates IR-induced testicular damage and assesses PGZ's potential protective rol...