Heterolinker MOFs synergized with entropy-driven DNA amplification for precision dual-mode sensing of Microcystin-LR [0.03%]
基于熵驱动DNA扩增的异联吡啶鎓MOFs用于精确检测微囊藻毒素-LR传感器
Yawei Sun,Yamei Li,Zhuangzhuang Ru et al.
Yawei Sun et al.
To overcome the high risk of false results in single-mode detection for environmental toxins, a self-validating dual-mode biosensing platform integrating photoelectrochemical (PEC) and fluorescence (FL) signals was developed for the ultrase...
Multi-hotspot coupled metasurface for fingerprint identification of trace carcinoembryonic antigen molecules [0.03%]
用于识别痕量癌胚抗原分子指纹的多热点耦合超表面
Xiaoxuan Li,Linlong Tang,Xiaojian Zhang et al.
Xiaoxuan Li et al.
Cancer remains a major global health challenge, highlighting the need for effective biomarker monitoring. Carcinoembryonic antigen (CEA), a widely used tumor-associated marker, is crucial for cancer diagnosis. Surface-enhanced infrared abso...
Bifunctional DNA multivalent structure integrating stable capture of urothelial carcinoma cells with CRISPR/Cas12a signal amplification for bladder cancer detection [0.03%]
一种用于膀胱癌检测的双功能DNA多价结构，集稳定捕获上皮细胞癌细胞与CRISPR / Cas12a信号扩增于一体
Xiaofei Sun,Lei Qian,Di Jin et al.
Xiaofei Sun et al.
Noninvasive detection of bladder cancer remains challenging due to the limited analytical performance of current urine-based assays under realistic detection conditions. Here, we report a linear programmable DNA nanostructure that integrate...
Ultrasensitive cell surface stress biosensor based on magnetic-stress-electrical coupling [0.03%]
基于磁-力-电耦合的超高灵敏度细胞表面应力生物传感器
Haoyu Wang,Dong Zhao,Sitong Wu et al.
Haoyu Wang et al.
Surface stress, as an indicator of cellular state, responds to morphological changes, signaling, and disease processes, and is therefore highly significant for early diagnosis and precise disease monitoring. However, cell surface stress can...
Covalently functionalized MoS2 nanopore with amino acids for label-free protein residue discrimination [0.03%]
基于氨基酸共价修饰的二硫化钼纳米孔单分子蛋白多肽无标记识别与检测研究
Junzhou He,Yubin Cao,Meiting Zeng et al.
Junzhou He et al.
Precise detection of amino acids is critical for proteomics and molecular recognition. Nanopore sensing enables label-free single-molecule analysis but often lacks sufficient spatial resolution to control translocation dynamics and resolve ...
Electrophoresis-assisted SERS-LFA strip for simultaneous HIV and HBV detection [0.03%]
一种用于同时检测HIV和HBV的电泳增强型SERS-LFA试纸条
Mengdan Lu,Ji Qi,Younju Joung et al.
Mengdan Lu et al.
This study presents an electrophoresis-assisted surface-enhanced Raman scattering (SERS)-based lateral flow assay (E-SERS-LFA) for the simultaneous detection of human immunodeficiency virus p24 antigen (HIV p24) and hepatitis B virus surfac...
Accurate diagnosis of triple-negative breast cancer enables temperature-compensation all optical microfibre gratings system [0.03%]
温度补偿全光学微光纤光栅系统助力准确诊断三阴性乳腺癌
Xin Liu,Qiao Xu,Yunlong Wang et al.
Xin Liu et al.
Accurate clinical diagnosis of triple-negative breast cancer (TNBC) usually needed tedious, time consuming, high-cost tissue section analyzation procedures by using conventional clinical medical approaches. Thus, it is an urgent to develop ...
Chip electrophoresis titration biosensors: Recent developments for biomedical targets [0.03%]
芯片电泳滴定生物传感器：面向生物医学目标的新进展
Muhammad Idrees Khan,Lianhua Liu,Ali Sani et al.
Muhammad Idrees Khan et al.
Chip Electrophoresis Titration (ET) is an alternative distance-based measurement approach for Point-of-Care Testing (POCT) where the idea of acid-base titration is applied in a microchannel to detect chemical and biological targets through ...
Wearable microneedle patches integrated with a bicatalytic nanozyme for self-cascade amplified dopamine sensing [0.03%]
一种用于自级联放大多巴胺检测的可穿戴微针贴片集成双催化纳米酶传感器
Meini Li,Qin Liang,Yunfei Xie et al.
Meini Li et al.
This study constructs a wearable microneedle sensing platform integrated with a bicatalytic nanozyme, enabling minimally invasive detection of dopamine (DA) in interstitial fluid. Firstly, a dual-enzyme mimic nanozyme (CMCO-S) with high cat...
Defining virulence factor as a pre-screening strategy for gram negative bacterial infection: A GO-Fe3O4-based electrochemical siderosensor for detection of virulent Escherichia coli [0.03%]
基于GO-Fe3O4的电化学铁传感器检测毒力因子作为革兰氏阴性菌感染前期筛查策略及检测致病大肠杆菌
C S Sreelakshmi,Pooja Nag,Maargavi Singh et al.
C S Sreelakshmi et al.
Infections caused by antibiotic resistant bacteria pose a multifaceted threat to global health. Sensors targeting key virulence factors such as siderophores, offer an unconventional yet selective detection approach for determination of bact...