A bioelectronic interface for continuous neuroinflammation monitoring and neuromodulation in Parkinson's disease model [0.03%]
帕金森病模型的连续神经炎症监测和神经调控的生物电子界面
Siyi Zou,Jingze Li,Yancong Yu et al.
Siyi Zou et al.
Neuroinflammation is increasingly recognized as a critical driver in the onset and progression of Parkinson's disease (PD), yet technologies capable of continuously tracking neuroinflammatory dynamics in vivo remain limited. Here, we report...
An ultrasensitive electrochemical nucleic acid biosensor with a triple amplification strategy for bacterial detection in water [0.03%]
用于水体中细菌检测的三重信号放大电化学核酸生物传感器
Youke Li,Tianzhi Li,Ling Liu et al.
Youke Li et al.
Rapid and sensitive determination of total bacterial count in water is essential for safeguarding water safety. In this work, an ultrasensitive electrochemical nucleic acid biosensor was developed for the detection of total bacteria in wate...
R Cancelliere,G Rea,A Sierra Padilla et al.
R Cancelliere et al.
The rising demand for sustainable, high-performance materials in electrochemical (bio)sensing (EB) has driven the exploration of carbon materials derived from renewable resources. While graphene, carbon nanotubes, and similar nanocarbons ar...
Recognition-induced in situ plasmonic modulation of a near-infrared-responsive organic photoelectrochemical transistor for ultrasensitive detection of ampicillin [0.03%]
基于金纳米棒的光电化学传感器的原位等离激元调控用于超灵敏青霉素检测研究
Lei Zhao,Xin-Xin Xie,Pei Song et al.
Lei Zhao et al.
Ampicillin (AMP) residues arising from widespread antibiotic use pose increasing concerns for food safety and environmental health, while their trace detection in complex matrices remains challenging. Here, we report a recognition-induced i...
AI-automated portable FRET platform for ultra-sensitive and rapid on-site lead sensing using a bacterial biosensor [0.03%]
一种便携式FRET平台用于现场快速灵敏的铅检测——使用细菌生物传感器的自动化人工智能系统
Yu-Sheng Liu,Pei-Yun Xie,Hung-Chi Hsu et al.
Yu-Sheng Liu et al.
Rapid on-site monitoring of lead (Pb) contamination is often limited by the fragility of mammalian-cell biosensors in an environmental setting and the manual image analysis that is labor intensive. This work demonstrates a stable, on-site p...
Minimally invasive monitoring of acute liver injury using ROS-responsive gold aggregates for urinary readout [0.03%]
用于尿液检测的ROS响应性金聚集体的微创急性肝损伤监测方法研究
Shaowen Wang,Hui Fang,Xiaochun Xie et al.
Shaowen Wang et al.
Acute liver injury is a life-threatening disorder associated with substantial morbidity and mortality worldwide, underscoring the need for convenient and minimally invasive monitoring. Here, we develop an ALI-responsive nanoprobe that disso...
Engineering bubble structures as Cas12a activators for highly sensitive monitoring of WRN helicase function [0.03%]
工程设计气泡结构作为Cas12a激活剂以实现WRN解旋酶功能的高灵敏监测
Jiajun Ke,Han Zhang,Shengrou Chen et al.
Jiajun Ke et al.
The Werner syndrome helicase (WRN) is a critical synthetic lethal target in microsatellite instability cancers, essential for resolving complex genomic structures like replication bubbles and R-loops. However, strategies to simultaneously d...
High-performance photoelectrochemical biosensor with Bi2S3/RuO2 heterojunction cascade multi-tetrahedral DNA nanonet for ultrasensitive lead ions detection [0.03%]
一种高性能的光电化学生物传感器用于超灵敏检测铅离子：具有Bi2S3 / RuO2异质结级联多四面体DNA纳米网
Luguang Cai,Yaqi Shen,Ying Jiang et al.
Luguang Cai et al.
Herein, a novel signal-off photoelectrochemical (PEC) biosensor was rationally constructed by integrating a Bi2S3/RuO2 heterojunction with the multiple tetrahedral DNA nanonet (mTDN) for ultrasensitive and accurate lead ions detection. This...
Flexible bioelectronic electrodes: From engineering strategies to cross-domain biomedical applications [0.03%]
柔性生物电子电极：从工程策略到跨领域生物医学应用
Xiaoyi Zuo,Xinyu Sun,Liu Cong et al.
Xiaoyi Zuo et al.
Flexible electrodes have emerged as key bioelectronic interfaces for recording, modulation, and sensing in complex biological environments. Their mechanical compliance, conformal contact, and tunable electrochemical properties enable effect...
Ordered macro-microporous Co-ZIF nanozyme with phytate enrichment-linker for efficient visual vanillin detection [0.03%]
一种有序的宏观-微观多级次Co-ZIF纳米酶用于可视化检测香草醛
Zhanli Zhao,Lintao Yang,Xinyang She et al.
Zhanli Zhao et al.
Nitrogen-rich zeolitic imidazolate frameworks (ZIFs) are promising for rapid small-molecule sensing due to their tunable porosity. Yet, their practical application is often hindered by mass transfer limitations and low metal utilization cau...