Yingyi Ma,Yu Si,Shun Yao et al.
Yingyi Ma et al.
Chiral discrimination is crucial in medicine, food, and materials science. Herein, we report a novel electrochemical chiral sensor with a three-dimensional (3D) porous interface integrating chirality, conductivity, and porosity for efficien...
Synergistic modulation of oxidation state of Pt nanozymes via Pd doping and ZIF-67 support enhances the catalytic efficiency for immunoassay detection [0.03%]
Zhenjiang Liu,Ying Yang,Weiguo Yu et al.
Zhenjiang Liu et al.
Modulating the oxidation state of active sites presents a promising strategy for enhancing catalytic performance. However, the intrinsic electronic properties of a single regulatory strategy make it difficult to accurately control the oxida...
Highly integrated chip for continuous chemical synthesis, purification and inline biosensoric monitoring of biological activity on stem cell-derived 3D cardiomyocyte cultures [0.03%]
一种用于连续化学合成、纯化和基于干细胞的三维心肌细胞培养生物活性联机生物传感器监测的高度集成芯片
T Haensch,F D Zitzmann,S Schmidt et al.
T Haensch et al.
Miniaturization and development of lab-on-a-chip (LOC) devices are a fast-evolving research field. While single processes e.g. pharmacological compound testing on cells and organoids, diagnostic applications, chemical synthesis or on-chip a...
Rossella Labarile,Anna De Salvo,Federico Rondelli et al.
Rossella Labarile et al.
The use of the abundant and easily available solar energy is central towards a carbon-free society and represents the most sustainable strategy for the increasing energy demand. Rhodobacter (R.) sphaeroides is a versatile photosynthetic pur...
Self-driven microfluidic chip with integrated lateral and vertical flow assays for dual-readout point-of-care testing [0.03%]
集成了横向和纵向流动测定的自驱动微流控芯片用于双读出的即时检测
Qifan Zhou,Yu Lu,Miaomiao Li et al.
Qifan Zhou et al.
Rapid and sensitive detection of biomarkers is pivotal for disease prevention and control in point-of-care testing (POCT). Traditional nitrocellulose (NC) membrane-based lateral flow assay (LFA) often cause suboptimal sensitivity and poor u...
pLDH to identify severity in imported malaria: Implementing smartphone video analysis for rapid clinical decision-making [0.03%]
利用智能手机视频分析快速临床决策以识别输入性疟疾的严重程度： LDH的作用
Julia Pedreira-Rincón,Leire Balerdi-Sarasola,Guillermo Villanueva et al.
Julia Pedreira-Rincón et al.
Malaria is the main parasitic disease-causing death in endemic and non-endemic regions. Imported malaria cases face an elevated risk of severe disease, but non-specific clinical presentations and limited clinician experience often delay dia...
Creating a novel halotolerant whole-cell biosensor for efficient degradation and precise quantification of p-nitrophenol-substituted organophosphate pesticides in hypersaline ecosystems [0.03%]
一种新型耐盐性全细胞生物传感器的创制及其在高盐生态系统中高效降解和精准定量p-硝基苯酚取代有机磷农药中的应用研究
Yujie Liu,Xinyu Zhang,Haomin Chen et al.
Yujie Liu et al.
The previously constructed biosensors for organophosphate pesticides (OPs) detection cannot be used to measure OPs concentrations under high salt conditions. In this study, a novel halotolerant whole-cell biosensor J9U-pBBR-pobRA-gfp, which...
CRISPR-Cas12a-integrated pregnancy test strip biosensors: Visual detection of telomerase and miRNA let-7a in cervical cancer diagnostics [0.03%]
整合CRISPR-Cas12a的孕期试纸生物传感器：人乳头瘤病毒所致宫颈癌相关端粒酶和miRNA let-7a的可视化检测
Xiaoya Gu,Tong Zhang,Haoyan Yao et al.
Xiaoya Gu et al.
Cervical cancer is a leading cause of female cancer-related mortality globally, and early screening based on reliable biomarkers is critical for improving prognosis. Telomerase (a key driver of cellular immortalization) and microRNA let-7a ...
Perovskite-COF hybrid enables sequence-programmed, anti-correlated ECL/SERS readout of NF-κB p50 [0.03%]
序控式NF-κB p50核小体电化学发光/表面增强拉曼散射双通道检测的钙钛矿-共价有机框架杂化模式
Yanfei Ma,Chan Yang,Fengqing Liao et al.
Yanfei Ma et al.
Physical medicine and rehabilitation (PM&R) needs mechanism-anchored biomarkers that change early enough to guide exercise dosing and physiotherapy. Here we position NF-κB p50 as a PM&R biomarker-read out not by bulk abundance but by DNA-b...
DNAzyme walker-triggered HCR dual amplification mediated by MOF-derived bimetallic Fe-Ni-doped porous carbon nanozyme for homogeneous dual-mode aptasensor detection of profenofos [0.03%]
基于MOF衍生的二金属Fe-Ni掺杂多孔碳纳米酶介导的DNAzyme行走触发HCR双扩增同种双模式适配子传感器检测丙硫磷
Yifan Xu,Baoshan He,Ming Lu et al.
Yifan Xu et al.
Profenofos (PFF), a widely utilized organophosphorus pesticide, readily accumulates in crops and poses neurotoxic risks to humans. However, rapid and precise detection of PFF in complex matrices remains challenging. Herein, we report a homo...