Yaohua Li,Yuexin Liu,Yang Guo et al.
Yaohua Li et al.
Follicle-stimulating hormone (FSH) and its receptor FSHR have traditionally been studied as regulators of reproductive physiology. Recent evidence indicates that FSH-FSHR signaling may be involved in selected cancer-related processes, but i...
Salidroside alleviates age-related metaphase II oocyte aging by enhancing mitochondrial complex I-mediated oxidative phosphorylation [0.03%]
红景天苷通过增强复合物I介导的氧化磷酸化缓解卵母细胞衰老
Feimiao Wang,Zhaoyang Wang,Jialing Li et al.
Feimiao Wang et al.
The deterioration of metaphase II (MII) oocyte quality is a principal factor compromising fertility in women of advanced maternal age and a core hallmark of ovarian aging; however, effective interventions to counteract this age-related decl...
Corrigendum to "Natural exosome-like nanovesicles from Salvia chinensis Benth induce Ferroptosis to suppress Hepatocellular Carcinoma progression via AMPK/Nrf2/xCT axis" [Cellular Signalling 134 (2025) 111928] [0.03%]
中国红景天天然外泌体样纳米囊泡通过AMPK/Nrf2/xCT轴诱导铁死亡以抑制肝癌进展的更正文章
Zicheng Liang,Xiayi Fang,Zhen Zhang et al.
Zicheng Liang et al.
Published Erratum
Cellular signalling. 2026 Jul 10:112727. DOI:10.1016/j.cellsig.2026.112727 2026
Inorganic phosphate beyond a mineral: Signal transduction in multi-organ pathology [0.03%]
无机磷酸盐与多器官病理信号转导之间的关系
Amanda Lima Silva,Beatriz Bereda da Silva Freitas,Pedro Henrique Silva Oliveira et al.
Amanda Lima Silva et al.
Inorganic phosphate (Pi) is a fundamental cellular metabolite whose excess triggers active signalling cascades that drive pathological remodelling across multiple organ systems. This review synthesises evidence from vascular, renal and onco...
An H3K18la-ALKBH5-Runx2-LDHA positive feedback loop promotes vascular calcification in the osteogenic phenotypic transition of vascular smooth muscle cells [0.03%]
血管平滑肌细胞成骨表型转化中促进血管钙化的H3K18la-ALKBH5-Runx2-LDHA正反馈环路
Yifan Deng,Jing Chen,Qinyu Sun et al.
Yifan Deng et al.
Osteogenic phenotypic transition of vascular smooth muscle cells (VSMCs) is the core pathological event underlying the initiation and progression of vascular calcification (VC). Runt-related transcription factor 2 (Runx2), a master osteogen...
NSUN2 integrates glucose and one‑carbon metabolism upstream of Rag GTPase-dependent mTORC1 signaling [0.03%]
NSUN2整合葡萄糖和一碳代谢的信号通路上游于Rag GTP酶依赖性mTORC1信号转导路径
Xueyi Chen,Li Xiao,Yiying Zhou et al.
Xueyi Chen et al.
How glucose and one‑carbon metabolism converge on Rag GTPase-dependent mechanistic target of rapamycin complex 1 (mTORC1) remains poorly defined, particularly in the absence of AMP-activated protein kinase (AMPK). This study mapped an AMPK...
PFKP promotes oncogenesis in osteosarcoma through PI3K/HIF-1α pathway-mediated H3K18la modification [0.03%]
PFKP通过PI3K/HIF-1α途径介导的H3K18la修饰促进骨肉瘤的致癌作用
Xue Zhang,Mingyue Guan,Yuanyuan Wang et al.
Xue Zhang et al.
The preferential utilization of aerobic glycolysis by cancer cells causes lactate accumulation, resulting in histone H3 lysine 18 lactylation (H3K18la), lactylation of other proteins, and alterations in gene expression. Given the rate-limit...
IP3R1-mediated Ca2+ overload promotes SAH-induced neuron apoptosis through MAMs [0.03%]
IP3R1介导的钙超载通过MAM促进脑卒中后血管性痴呆的神经元凋亡
Zhonghua Zhang,Peipei Shen,Lin Zong et al.
Zhonghua Zhang et al.
Background: Aneurysmal subarachnoid hemorrhage (SAH) is a devastating acute hemorrhagic stroke. The communication between the endoplasmic reticulum (ER) and mitochondria, mediated by mitochondria-associated membranes (MAM...
YBX1 phase separation promotes radioresistance in lung adenocarcinoma by suppressing ferroptosis through GPX4 regulation [0.03%]
YBX1相分离通过GPX4调控抑制铁死亡从而促进肺腺癌放射抵抗性
Lifei Tong,Yiqian Wang,Xia Zhang et al.
Lifei Tong et al.
Lung adenocarcinoma (LUAD) remains a leading cause of cancer-related mortality, and resistance to radiotherapy is a major clinical obstacle. Stress granules (SGs) are involved in tumor adaptation and therapy resistance, but the core regulat...
SGLT2 inhibition attenuates diabetes-induced lipid nephrotoxicity by targeting SOAT1-mediated cholesterol metabolism in proximal tubular cells [0.03%]
通过靶向近端小管细胞中SOAT1介导的胆固醇代谢来缓解糖尿病引起的脂质肾毒性：SGLT2抑制作用
Ping Wang,Hongtu Hu,Jingjing Ke et al.
Ping Wang et al.
Diabetic kidney disease (DKD) is a severe complication of diabetes mellitus and a leading cause of end-stage kidney disease (ESKD). Ectopic lipid accumulation, particularly cholesterol deposition in renal proximal tubular cells, contributes...