Inhibition of ETS1/DRP1 axis attenuates intervertebral disc degeneration by suppressing excessive mitochondrial fission [0.03%]
抑制ETS1/DRP1轴通过抑制过度线粒体分裂来缓解椎间盘退变
Pengfei Li,Yichen Que,Shuhao Zhang et al.
Pengfei Li et al.
Intervertebral disc degeneration (IVDD) is a predominant contributor to low back pain, characterized by nucleus pulposus cell (NPC) senescence, extracellular matrix (ECM) metabolic dysfunction, and chronic inflammation. Excessive mitochondr...
Corrigendum to 'Keratinocyte growth factor (KGF) induces podosome formation via integrin-Erk1/2 signaling in human immortalized oral epithelial cells' [Cellular Signaling 61 (2019) 39-47] [0.03%]
关于“角质细胞生长因子(KGF)通过整合素-Erk1 / 2信号传导诱导人类口腔上皮细胞永生化podosomes的形成”[信号转导杂志61(2019)39-47]的勘误表
Guoliang Sa,Zhikang Liu,Jiangang Ren et al.
Guoliang Sa et al.
Published Erratum
Cellular signalling. 2026 Jul 27:112749. DOI:10.1016/j.cellsig.2026.112749 2026
Effect of moderate-intensity aerobic exercise on early oxidative stress and muscle atrophy in SAMP8 mice through modulation of the DAO/SRR and Nrf2/Keap1 pathways [0.03%]
有氧运动通过调节DAO/SRR和Nrf2/Keap1信号通路对SAMP8小鼠早期氧化应激及肌萎缩的影响
Xiangli Tong,Jinkun Xue,Zixuan Chen et al.
Xiangli Tong et al.
Age-related muscle atrophy is closely associated with oxidative stress imbalance. This study investigated the molecular mechanisms by which moderate-intensity aerobic exercise alleviates early oxidative stress and muscle atrophy in senescen...
Gα13 signaling in the nervous system: Roles in neurodevelopment, stress responses, and neurological disorders [0.03%]
神经系统的Gα13信号转导：在神经发育、应激反应和神经系统疾病中的作用
Xiaokang Ke,Honglin Yan,Jingping Yuan et al.
Xiaokang Ke et al.
miR-143-3p integrates contractility and growth in benign prostate stromal cells [0.03%]
miR-143-3p在前列腺良性基质细胞中整合收缩力和增殖能力
Wenbin Zhu,Yajie Xu,Anna Ciotkowska et al.
Wenbin Zhu et al.
Background: Prostate smooth muscle contraction and stromal growth are key determinants of voiding symptoms in benign prostatic hyperplasia (BPH), but their regulation by microRNAs is unknown. Here, we assessed the functio...
Hederacolchiside A1 targets ERO1A to suppress PI3K/AKT/mTOR signaling and induce ferroptosis in colorectal cancer [0.03%]
蔊菜秋水仙苷A1靶向ERO1A以抑制PI3K / AKT / mTOR信号传导并诱导结直肠癌铁死亡
Peipei Li,Linguo Cao,Tao Bi et al.
Peipei Li et al.
Colorectal cancer (CRC) remains a major global health challenge due to high incidence, poor prognosis, and limited therapeutic options. Ferroptosis, an iron-dependent form of regulated cell death, has emerged as a promising anti-tumor strat...
HSV-1 induced autophagy-associated DPD degradation promotes antitumor efficacy of oncolytic HSV-CD/5-FC in experimental glioblastoma [0.03%]
HSV-1诱导的自噬相关DPD降解增强溶瘤HSV-CD/5-FC治疗实验性胶质母细胞瘤的疗效
Peiwen Wang,Sheng Fang,Rui Wu et al.
Peiwen Wang et al.
PTPN14 functions as an oncogenic promoter in colon adenocarcinoma and liver hepatocellular carcinoma via Notch Signaling [0.03%]
PTPN14通过诺特定理信号促进结肠腺癌和肝细胞肝癌的致癌作用
Yuliuming Wang,Jingtao Li,Chunlin Wang et al.
Yuliuming Wang et al.
Protein tyrosine phosphatase non-receptor type 14 (PTPN14) exhibits dual roles in cancer, acting as either a tumor suppressor or oncogene depending on context, while its role in colon adenocarcinoma (COAD) and liver hepatocellular carcinoma...
Impaired mitochondrial quality control and stress signalling machinery modulate senescence induction by genotoxic challenge [0.03%]
遗传毒性损伤诱发衰老的分子机制研究进展
Mia Simons Weston,Marta Dominguez Prieto,Nicoleta Moisoi
Mia Simons Weston
Cellular senescence is a hallmark of ageing and age-related disease and is closely associated with mitochondrial dysfunction and the accumulation of DNA damage. However, the contribution of mitochondria-nucleus communication, mitochondrial ...
Integrative multi-omics profiling reveals DRG1 promotes hepatocellular carcinoma via c-Myc phosphorylation and facilitates lenvatinib resistance [0.03%]
整合多组学分析揭示DRG1通过促进c-Myc磷酸化来促进肝癌并诱导仑伐替尼耐药性
Peng Wang,Junying Xu,Hao Huang et al.
Peng Wang et al.
Background & aims: Developmentally regulated GTP-binding protein 1 (DRG1), a member of the GTPase family, has been implicated in cancer progression; however, its biological function and therapeutic relevance in hepatocell...