HOXA13 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating SLC7A11 and SLC3A2 [0.03%]
HOXA13通过上调SLC7A11和SLC3A2抑制铁死亡从而促进前列腺癌转移
Yongliang Ma,Rui Liu,Pan Qi et al.
Yongliang Ma et al.
Background: HOXA13, a member of the homeobox gene family, has emerged as a potential oncogenic driver in prostate cancer (PCa). However, its regulatory role in ferroptosis and interactions with SLC7A11 and SLC3A2 remain u...
Junqiang Lin,Ye Qiu,Chun Ye et al.
Junqiang Lin et al.
Aging involves a profound reorganization of metabolic processes, marked by a progressive decline in anabolic activity and a compensatory increase in catabolic flux. This imbalance drives cellular dysfunction and contributes to age-related p...
Corrigendum to' Rab27a+ CAF-derived exosomal miR-9-5p promotes osteosarcoma progression via CREBRF/MAPK signaling pathway', [Cellular Signaling Oct:134(2025):111964-111975] [0.03%]
关于“ Rab27a+CAF源外泌体miR-9-5p通过CREBRF/MAPK信号通路促进骨肉瘤进展”的勘误说明
Xiaoying Niu,Wen Tian,Zhongyi Li et al.
Xiaoying Niu et al.
Published Erratum
Cellular signalling. 2025 Oct 11:112158. DOI:10.1016/j.cellsig.2025.112158 2025
CPSF6 loss mediates LDHA 3'UTR shortening to promote fibroblast glycolysis and pulmonary fibrosis [0.03%]
CPSF6缺失介导LDHA 3'UTR缩短以促进成纤维细胞糖酵解和肺纤维化
Huanyu Yang,Mengjia Han,Li Zhang et al.
Huanyu Yang et al.
Pulmonary fibrosis is a chronic and progressive fibrotic lung disease with a poor prognosis and few treatment options. Alternative polyadenylation (APA), an important post-transcriptional regulatory mechanism, remains poorly understood in p...
Regulatory T cell death in inflammation and tumor immunity: Focus on necroptosis, pyroptosis and ferroptosis [0.03%]
免疫炎症和肿瘤免疫中调节性T细胞的死亡：重点关注坏死性凋亡、焦亡和铁死亡
Chuanxiang Zhao,Xinglong Wang
Chuanxiang Zhao
Regulatory T (Treg) cells are a developmentally and functionally distinct cell lineage with the suppressive capacity among CD4+ T cell subgroups, which contributes to immune tolerance, tissue homeostasis and regeneration. Therefore, the pre...
PPP1R14B promotes the progression of prostate cancer by regulating the JAK2/STAT3/AR pathway and alters the sensitivity and resistance to enzalutamide [0.03%]
PPP1R14B通过调节JAK2/STAT3/AR通路促进前列腺癌进展并改变对恩杂鲁胺的敏感性和耐药性
Long Cheng,Chengyu You,Longtu Ma et al.
Long Cheng et al.
Prostate cancer (PCa) is the tumor with the highest incidence rate among men worldwide. There is still a lack of effective treatment options for metastatic PCa and castration-resistant prostate cancer (CRPC). Protein phosphatase 1 regulator...
Mechanistic insights into homocysteine-induced coronary microcirculatory dysfunction post-MI: The pivotal role of LncMEG3/miR-223/NLRP3 signaling axis [0.03%]
同型半胱氨酸诱导的心肌梗死后冠状动脉微循环障碍：LncMEG3/miR-223/NLRP3信号轴起关键作用
Jingan Rao,Congcong Ding,Xiao Huang et al.
Jingan Rao et al.
Background: Hyperhomocysteinemia (HHcy) is known to exacerbate coronary microvascular dysfunction in patients experiencing acute myocardial infarction (AMI). However, the precise mechanisms underlying the exacerbation of ...
Resolvin E1 improves the maturation of porcine oocytes by suppressing oxidative stress via Nrf2 pathway activation [0.03%]
白细胞介素E1通过激活Nrf2信号通路抑制氧化应激促进猪卵母细胞成熟
Hyo-Gu Kang,Ji Hyeon Yun,Eun Young Choi et al.
Hyo-Gu Kang et al.
Resolvin E1 (RvE1) is a specialized pro-resolving mediator from the bioactive lipid family that has been detected in follicular fluid and serum and is secreted by cumulus cells during culture. However, its role in mammalian oocyte maturatio...
Unraveling the hnRNPK/miR-133a-3p/UCP2 axis: a novel regulatory circuit governing porcine skeletal muscle satellite cell fate [0.03%]
解译hnRNPK/miR-133a-3p/UCP2轴：一个新的调控通路决定猪骨骼肌卫星细胞命运
Yongjie Xu,Xiaofang Cheng,Mengjia Zhang et al.
Yongjie Xu et al.
Objective: MicroRNAs (miRNAs) post-transcriptionally regulate gene expression by targeting mRNA 3'UTRs, critically influencing skeletal muscle development. While miR-133a-3p is implicated in myogenesis, its regulatory int...
Study on the molecular mechanism of KPNA2 regulation of myocardial ischemia/delayed reperfusion injury through mitophagy [0.03%]
KPNA2通过线粒体自噬调控心肌缺血/延迟再灌注损伤的分子机制研究
Ende Tao,Zhe Tao,Fudon Wang et al.
Ende Tao et al.
This study investigates the role of Karyopherin Subunit Alpha 2 (KPNA2) in myocardial ischemia/delayed reperfusion (I/dR) injury and its underlying molecular mechanisms. Using SD rat I/dR models and cell hypoxia/reoxygenation (H/R) models, ...