A combined experimental and computational chiroptical approach to establish the biosynthesis and absolute configuration of licochalcone L [0.03%]
结合实验和计算圆二色法确立甘草/licochalcone L的生物合成及绝对构型
Pankaj Pandey,William M Neal,Fazila Zulfiqar et al.
Pankaj Pandey et al.
Often, chiral natural products exist as single stereoisomers; however, simultaneous occurrences of both enantiomers can exist in nature, resulting in scalemic or racemic mixtures. Ascertaining theabsolute configuration (AC) of natural produ...
3-Hydroxybutyrate-containing triterpenoid saponins from Brachyscome angustifolia and their immunogenic activity [0.03%]
含3-羟基丁酸的三萜皂苷及其免疫原活性成分从巢丝叶草中提取
Mira Oh,Soohyun Um,Jae-Hyeon Jeong et al.
Mira Oh et al.
Three unique hydroxybutyrate-containing triterpenoid saponins, angustiside A-C (1-3), were isolated from the shoots of Brachyscome angustifolia (Asteraceae). The extensive spectroscopic study showed that their aglycone is a previously undes...
Chemical constituents with senolytic activity from the stems of Limacia scandens [0.03%]
Limacia scandens藤茎中的抗衰老化学成分筛选及机制研究
Hee Ju Lee,Mi Zhang,Thi Phuong Doan et al.
Hee Ju Lee et al.
While screening senotherapeutics from natural products, seven undescribed chemicals, two syringylglycerol derivatives, two cyclopeptides, one tigliane analogue, and two chromone derivatives, as well as six known compounds were isolated from...
Ten undescribed eremophilane and guaiane sesquiterpenes from Penicillium roqueforti [0.03%]
源自白色青霉的10个新倍半萜组成成分
Shuyuan Mo,Zhangyan Huang,Zi Ye et al.
Shuyuan Mo et al.
Nine undescribed eremophilane sesquiterpenes, one undescribed guaiane sesquiterpene, along with ten known analogues were isolated and identified from fungus Penicillium roqueforti, which was separated from the root soil of Hypericum beanii ...
Daphnane-type diterpenoids from Stellera chamaejasme L. and their inhibitory activity against hepatocellular carcinoma cells [0.03%]
星毛菊中的杜松烷二萜及其对肝癌细胞的抑制作用
Zhuo-Yang Cheng,Jing-Xian Ren,Xiao-Bian Xue et al.
Zhuo-Yang Cheng et al.
Daphnane-type diterpenoids, which are scarce in nature, exhibit potent growth-inhibitory activities against various cancer cells. To identify more daphnane-type diterpenoids, the phytochemical components in the root extracts of Stellera cha...
Liver-cell protective pyridones from the fungi Tolypocladium album dws120 [0.03%]
来源于托氏青霉菌的护肝吡啶酮类化合物
Xiao-Qian Wu,Jing Li,Xi Zhou et al.
Xiao-Qian Wu et al.
Five previously undescribed pyridone derivatives, tolypyridones I-M, were identified from the solid rice medium fermented by Tolypocladium album dws120, along with two known compounds tolypyridone A (or trichodin A) and pyridoxatin. Their p...
Cinnamigones A-C, three highly oxidized guaiane-type sesquiterpenes with neuroprotective activity from Cinnamomum migao [0.03%]
来自肉桂树的三个高度氧化的神经保护单萜类化合物Cinnamigones A-C
Lang Zhou,Li-Shou Yang,Li Wang et al.
Lang Zhou et al.
Cinnamigones A-C, three undescribed highly oxidized guaiane-type sesquiterpenes were isolated from the fruits of Cinnamomum migao. Cinnamigone A (1), structurally artemisinin-like, is a natural 1,2,4-trioxane caged endoperoxide with an unpr...
Synthesis and characterization of an artificial glucosinolate bearing a chlorthalonil-based aglycon as a potent inhibitor of glucosinolate transporters [0.03%]
一种氯thal尼基葡萄糖硫苷的人工合成及特性分析：作为一种强力抑制剂的葡萄糖硫苷运输蛋白特征分析
Yingjie Wen,Xunyuan Jiang,Dehong Li et al.
Yingjie Wen et al.
Glucosinolates (GSLs) are specialized metabolites in plants of the order Brassicales. GSL transporters (GTRs) are essential for the redistribution of GSLs and also play a role in controlling the GSL content of seeds. However, specific inhib...
Structurally diverse spirocyclic polycyclic polyprenylated acylphloroglucinols from Hypericum ascyron Linn. and their anti-tumor activity [0.03%]
含有新颖螺并多环骨架的圣约翰草二氢芭蕉素型新天然产物及其抗肿瘤活性研究
Ya-Li Hu,Grace Gar-Lee Yue,Xing-Ren Li et al.
Ya-Li Hu et al.
Ten spirocyclic polycyclic polyprenylated acylphloroglucinols (PPAP), hunascynols A-J (1-10), and 12 known analogs were isolated from the aerial parts of Hypericum ascyron Linn. Compounds 1 and 2, which share a 1,2-seco-spirocyclic PPAP ske...
Diana Persia,Francesca Mangiavacchi,Maria Carla Marcotullio et al.
Diana Persia et al.
Since ancient times, Cannabis and its preparations have found various applications such as for medical, recreational and industrial purposes. Subsequently the 1930s, legislation in many countries has restricted its use due to its psychotrop...