Jia-Yuan Li,Shi-Fei Wu,Ya-Ling An et al.
Jia-Yuan Li et al.
Eight undescribed steroidal alkaloid derivatives, including three cevanine-type isosteroidal alkaloids (two N-oxide glycosides and one D-ring aromatization) (1-3), one verazine-type steroidal alkaloid derivative (4), three solanidine-type s...
Effect of postharvest nicotinamide treatment on NAD+ metabolism and redox status in strawberry fruit during storage [0.03%]
采后组蛋白乙酰化对草莓贮藏期间NAD+代谢和抗氧化能力的影响
Tomasz Piechowiak,Bartosz Skóra,Maciej Balawejder
Tomasz Piechowiak
The increased activity of PARP enzymes is associated with a deficiency of NAD+, as well as with a loss of NADPH and ATP, and consequent deterioration of the redox state in fruits. In this study, we checked whether treatment with nicotinamid...
Anti-inflammatory quinoline-4(1H)-one derivatives from the aerial parts of Waltheria indica linn [0.03%]
印度尼西亚印加草属植物的抗炎喹啉-4(1H)-酮类成分
Yiming Hua,Kewu Zeng,Haizhen Liang et al.
Yiming Hua et al.
Eight previously undescribed quinoline-4(1H)-one derivatives (1-8) and five known analogues (9-13) were isolated from the 95% aqueous extract of the aerial parts of Waltheria indica Linn. Their chemical structures were determined by analyzi...
Bioactivity-guided isolation of trypanocidal coumarins and dihydro-pyranochromones from selected Apiaceae plant species [0.03%]
从选定的伞形科植物中通过生物活性导向分离查尔酮和氢吡喃香豆素类滴虫杀灭剂化合物
Sandhya R Krishnan,Adrianna Skiba,Simon Vlad Luca et al.
Sandhya R Krishnan et al.
Bioactivity-guided isolation of natural products from plant matrices is widely used in drug discovery. Here, this strategy was applied to identify trypanocidal coumarins effective against the parasite Trypanosoma cruzi, the etiologic agent ...
Hunteriasines A - D, tryptamine-derived alkaloids from Hunteria umbellata [0.03%]
拟裸芸香素A-D抗氧化白粉藤生物碱簇
Daijing Wei,Yun Yang,Ruiying Xi et al.
Daijing Wei et al.
Four undescribed tryptamine-derived alkaloids, hunteriasines A - D, were isolated and identified from Hunteria umbellata (Apocynaceae), together with fifteen known indole alkaloids. The chemical structure and absolute configuration of hunte...
Cytotoxic pyridine alkaloids from a marine-derived fungus Arthrinium arundinis exhibiting apoptosis-inducing activities against small cell lung cancer [0.03%]
一种海洋来源真菌Arthrinium arundinis中具有促凋亡活性的细胞毒吡啶类生物碱成分研究
Yiwei Hu,Shuai Ma,Xiaoyan Pang et al.
Yiwei Hu et al.
Small cell lung cancer (SCLC) is a kind of high-grade neuroendocrine carcinoma, which is characterized by a higher proliferative rate, earlier metastasis and more poor outcomes compared to non-small cell lung cancer (NSCLC). Under the guida...
Phytochemical study of Boswellia dalzielii oleo-gum resin and evaluation of its biological properties [0.03%]
博斯韦利亚达尔齐尔树脂的植物化学研究及其生物活性评估
Kimberley Massei,Thomas Michel,Girma Ilayas Obersat et al.
Kimberley Massei et al.
Boswellia dalzielii is a resin-producing tree endemic to West and Central Africa, used by local populations for various medicinal purposes. In this study, B. dalzielii gum resin was analyzed by GC-MS and UHPLC-MS to identify and quantify vo...
Triterpenoids with diverse skeletons from the roots of Rhus chinensis and their protective effects on isoproterenol-induced heart failure in zebrafish [0.03%]
多种骨架三萜类化合物从梾木果实中的根中分离获得及其对斑马鱼异丙肾上腺素致心力衰竭的保护作用
Miao Ye,Lingjie Ruan,Lina Huang et al.
Miao Ye et al.
In the ongoing quest to discover previously unreported lead compounds that provide protection against heart failure (HF), ten formerly undescribed (1-10) and nine known (11-19) triterpenoids were obtained from the roots of Rhus chinensis Mi...
Francesco Epifano,Salvatore Genovese,Serena Fiorito
Francesco Epifano
Dammarane-type saponins from Gynostemma pentaphyllum and their anti-aging activities via up-regulating mitochondria related proteins [0.03%]
绞股蓝达玛烷型皂苷及其通过调节线粒体相关蛋白发挥抗衰老作用
Hai-Zhen Liang,Peng-Xin Lu,Li-Li Chu et al.
Hai-Zhen Liang et al.
The importance of mitochondria in regulation of aging has been extensively recognized and confirmed. Gynostemma pentaphyllum (Thunb.) Makino, a homology of medicine and food, has been widely utilized as dietary supplement. In this study, th...