Discovery and biological evaluation of a new type of dual inhibitors of indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase from ethnomedicinal plant Dactylicapnos scandens [0.03%]
来自药用植物崖爬藤的新吲哚胺2,3-双氧酶1和色氨酸2,3-双氧酶双重抑制剂的发现与生物活性评价
Mei-Fen Bao,Xin-Ni Yang,Jing Wu et al.
Mei-Fen Bao et al.
The root of Dactylicapnos scandens (D.Don.) Hutch (Papaveraceae), one of the most famous ethno-medicinal plants from the Bai communities in P. R. China, is used to treat various inflammations and tumours. Bioassay-guided phytochemical resea...
Ent-eudesmane sesquiterpenoids from the Chinese liverwort Chiloscyphus polyanthus [0.03%]
中华小碗苔中的_ent-eudesmane_倍半萜类化合物
Ming-Zhu Zhu,Yi Li,Jin-Chuan Zhou et al.
Ming-Zhu Zhu et al.
- Seven previously undescribed ent-eudesmane sesquiterpenoids (1-7), as well as seven known analogs (8-14), were isolated from the Chinese liverwort Chiloscyphus polyanthus var. rivularis. Their structures were established based on comprehe...
Isolation and characterization of dihydropyran-ring containing meroterpenoids from Ganoderma lucidum and their inhibitory activity against renal fibrosis-related protein expression [0.03%]
从灵芝中分离鉴定含二氢吡喃环的倍半萜木脂素类化合物及其对肾纤维化相关蛋白表达的抑制作用
Yun-Li Peng,Yong-Xiang Wang,Yong-Xian Cheng
Yun-Li Peng
The Ganoderma lucidum mushroom, which has been used as a traditional medicine in China for more than 2000 years, is a source of many interesting natural product. In this study, the five undescribed minor meroterpenoids baoslingzhines F-J (1...
Anti-inflammatory polyoxygenated cyclohexene derivatives from Uvaria macclurei [0.03%]
Uvaria macclurei的抗炎性多含氧环己烯衍生物
Yexin Cheng,Hailong Li,Dan Wu et al.
Yexin Cheng et al.
Two undescribed polyoxygenated seco-cyclohexene derivatives named macclureins A and B, and three undescribed polyoxygenated cyclohexene derivatives macclureins C-E, together with 15 known analogues were isolated from the twigs and leaves of...
Natural complex substances: From molecules to the molecular complexes. Analytical and technological advances for their definition and differentiation from the corresponding synthetic substances [0.03%]
天然复杂物质：从分子到分子复合物。定义及区分相应合成物质的分析和科技进展
Luisa Mattoli,Caroline Pelucchini,Valentina Fiordelli et al.
Luisa Mattoli et al.
Natural complex substances (NCSs) are a heterogeneous family of substances that are notably used as ingredients in several products classified as food supplements, medical devices, cosmetics and traditional medicines, according to the corre...
Triterpenoid saponins from Psammosilene tunicoides and their antinociceptive activities [0.03%]
掌叶半边莲抗痛风三萜皂苷及其活性研究
Yan-Hong Li,Xi-Shan Bai,Xiu-Xia Yang et al.
Yan-Hong Li et al.
Herein, five undescribed oleanane-type triterpenoid saponins, namely, psammosaponins A-E, along with nine known compounds, were isolated from the roots of Psammosilene tunicoides. Moreover, part of the ethanolic extract of P. tunicoides was...
DESIGNER fraction concept unmasks minor bioactive constituents in red clover (Trifolium pratense L.) [0.03%]
设计师分数概念揭开了红三叶草（Trifolium pratense L.）中微量生物活性成分的面纱
Ryan Hitzman,Gonzalo R Malca-Garcia,Caitlin Howell et al.
Ryan Hitzman et al.
In botanical extracts, highly abundant constituents can mask or dilute the effects of other, and often, more relevant biologically active compounds. To facilitate the rational chemical and biological assessment of these natural products wit...
Phytocannabinoids biosynthesis during early stages of development of young Cannabis sativa L. seedlings: Integrating biochemical and transcription data [0.03%]
大麻幼苗早期发育阶段的次生代谢产物的大麻二酚生物合成：结合生化和转录数据
Flavia Fulvio,Giuseppe Mandolino,Cinzia Citti et al.
Flavia Fulvio et al.
Cannabis sativa (L.) is characterized by great genetic and phenotypic diversity, also expressed in the array of bioactive compounds synthesized. Despite its great potential economic interest, knowledge of the biology and genetics of this cr...
Undescribed 2,9-deoxyflavonoids and flavonol-diamide [3+2] adduct from the leaves of Aglaia odorata Lour. Inhibit nitric oxide production [0.03%]
具有抗炎作用的皱皮柑属植物(Lour.)叶中的两类新黄酮类成分及其结构相关的类似物
Pham Hai Yen,Ngo Anh Bang,Do Thi Trang et al.
Pham Hai Yen et al.
Phytochemical study on the methanol extract of Aglaia odorata leaves resulted in the isolation of four previously undescribed compounds, including three 2,9-deoxyflavonoids and one flavonol-diamide [3 + 2] adduct, and 13 known compounds. Th...
Lanostane triterpenoids with anti-proliferative and anti-inflammatory activities from medicinal mushroom Ganoderma lingzhi [0.03%]
灵芝抗肿瘤和抗炎兰脂素三萜化合物研究
Zhen-Zhu Zhao,Bao-Yu Ji,Zhen-Zhen Wang et al.
Zhen-Zhu Zhao et al.
Eight previously undescribed lanostane triterpenoids and nine known ones were identified from the fruiting bodies of Ganoderma lingzhi S.H. Wu, Y. Cao & Y.C. Dai. Their structures were determined based on spectroscopic data and quantum chem...