Ganocochlearcins A-P: Acyclic meroterpenoids from Ganoderma mushrooms targeting extracellular matrix remodeling in cancer-associated fibroblasts [0.03%]
Ganocochlearcin A-P：从灵芝中分离的非环状倍半萜杂交衍生物，靶向癌相关成纤维细胞中的细胞外基质重塑作用
Fu-Ying Qin,Dan Cai,Jiao-Jiao Zhang et al.
Fu-Ying Qin et al.
Sixteen undescribed acyclic meroterpenoids, ganocochlearcins A-P (1-10 and 12-17) and two known meroterpenoids, cochlearin K (11) and fornicin C (18), were obtained from Ganoderma mushrooms, including nine pairs of enantiomers, 3, 6-8, 11-1...
Seven undescribed steroidal glycosides with CYP3A4 inhibitory activity from the stems of Marsdenia tenacissima [0.03%]
来源于黄连木茎的7种新活性甾体苷成分及其CYP3A4抑制作用研究
Bian-Xia Xue,Dong Zhang,Qing-Xia Li et al.
Bian-Xia Xue et al.
Seven undescribed steroidal glycosides (compounds 1-7) and nine known glycosides (compounds 8-16) were isolated from the ethyl acetate fraction of Marsdenia tenacissima, which is frequently utilized as an adjunctive treatment alongside conv...
Isolation and functional characterization of terpene synthases from mediterranean plant Styrax officinalis [0.03%]
肉桂科植物圣木中异戊二烯合成酶的分离与功能表征
Bharadwaj Revuru,Prasada Rao Konagala,Hanan Swaed et al.
Bharadwaj Revuru et al.
Terpenes are specialized metabolites widely distributed across life, including plants, bacteria, fungi, and insects, where they play diverse ecological and physiological roles. In plants, they contribute to defense, reproduction, and intera...
Anti-inflammatory flavan alkaloids from the bulbs of Hymenocallis littoralis (Jacq.) Salisb [0.03%]
海滨中国百合鳞茎中的抗炎黄烷生物碱成分研究
Ruyang Guan,Meiqi Zhu,Mengke Zhang et al.
Ruyang Guan et al.
Hymenocallis littoralis (Jacq.) Salisb. (Coastal Spider Lily) is a rich source of structurally diverse specialized metabolites. In the present study, a phytochemical investigation of the bulbs of H. littoralis (collected in Guangdong, China...
Dracacochins A-H, undescribed flavonoid dimers and monomers from the red resin of Dracaena cochinchinensis and their anti-renal fibrosis activities [0.03%]
来自龙血树红色树脂的八种新的黄酮二聚体和单体化合物及其抗肾纤维化活性研究
Yu-Jie Wang,Tian-Chang He,Jing-Jing Qi et al.
Yu-Jie Wang et al.
Eight undescribed flavonoids including three dimers (1-3) and five monomers (4-8), together with ten known compounds (9-18) were isolated from the resins of Dracaena cochinchinensis (Chinese dragon's blood). Structurally, compounds 1-3 are ...
Immunosuppressive ergosterol-emodin hybrids from the endophytic Penicillium sp. XB152 [0.03%]
内生曲霉XB152中具有免疫抑制活性的麦角固醇-番木鳖苷杂合衍生物
Chunlun Qin,Qianxi Ouyang,Jinling Chang et al.
Chunlun Qin et al.
Ergostemodins A-D (1-4), four unprecedented heterodimers of ergosterol and emodin units featuring a unique 6/6/6/5/6/6/5/6 octacyclic skeleton, along with an unreported ergosterol, penicillisterene A (5), and a known ergosterol, acrocalyste...
Neodolastane diterpenoids from cultures of basidiomycete hydropus cf. trichoderma [0.03%]
来源于伞菌Hydropus cf. Trichoderma培养物的新倍半萜茋类化合物
Arunrat Yangchum,Thapanee Pruksatrakul,Malipan Sappan et al.
Arunrat Yangchum et al.
A highly conjugated 17-nor-neodolastane diterpenoid possessing a nitrile group, hydropusin A (1), and a neodolastane, hydropusin B (2a/2 b/2c), were isolated from cultures of the basidiomycete Hydropus cf. Trichoderma TBRC-BCC 43790. Hydrop...
Bsglucidines A-I: Eight previously undescribed meroterpenoids and a des-D-steroid from Ganoderma lucidum with anti-renal fibrotic activities [0.03%]
灵芝酸A—I：八种新的具有抗肾纤维化活性的杂萜及一种脱糖基固醇类化合物
Meng-Ying Chen,Yong-Sheng Xu,Yun-Yun Liu et al.
Meng-Ying Chen et al.
Eight previously undescribed Ganoderma meroterpenoids (GMs) including four enantiomeric bsglucidines A-D (1 and 3-5), two 6/6/6 and two 6/5/6 scaffold meroterpenoids bsglucidines F-I (7-10), an ergosteroid bsglucidine E (6), and one known G...
Identification and characterization of three acyltransferases involved in the hydroxycinnamic acid amide synthesis of goji berry [0.03%]
三种参与枸杞羟基肉桂酰胺合成的酰基转移酶的鉴定与功能分析
Pei Ma,Jiao Zhang,Wei Liu et al.
Pei Ma et al.
Hydroxycinnamic acid amides (HCAAs) featuring spermine or spermidine represent a major class of specialized metabolites in goji berries (Lycium spp.) and exhibit diverse pharmacological activities. Acylation is essential for HCAAs biosynthe...
Discovery of twelve undescribed diterpenoid alkaloids and identification of shawurensine A as a potent α7 nAChR antagonist [0.03%]
十二个新二萜类生物碱的发现及shawurensine A作为α7nAChR拮抗剂的作用机制研究
Yuqin Yang,Nurfida Ablajan,Wenjuan Xue et al.
Yuqin Yang et al.
A systematic phytochemical investigation of the whole plant of Delphinium naviculare var. lasiocarpum W.T. Wang (Ranunculaceae) led to the isolation and identification of 26 diterpenoid alkaloids (1-26), including twelve highly functionaliz...