1H NMR-guided isolation of ophiobolins from Bipolaris maydis and their bioactivities [0.03%]
基于~1H NMR导向的玉米丝核菌中奥波博林类化合物的分离及其生物活性研究
Yong Shen,Xiaotian Zhang,Qin Li et al.
Yong Shen et al.
Ophiobolins present characteristic 1H NMR resonances, which distinctly differ from other metabolites reported from Bipolaris maydis, and were used for an NMR-guided isolation in this research. As a result, 17 undescribed ophiobolin-sesterte...
Triterpenoid saponins from the roots and rhizomes of Clematis terniflora var. manshurica (Rupr.) Ohwi and their anti-inflammatory activities [0.03%]
狭叶铁线莲根及根茎中的三萜皂苷及其抗炎活性研究
Sheng Dong,Anqi Lu,Kexin Li et al.
Sheng Dong et al.
The 60% EtOH-eluted fraction (60%EF) from the roots and rhizomes of Clematis terniflora var. manshurica (Rupr.) Ohwi exhibited potent anti-inflammatory activity with minimal cytotoxicity compared to other fractions. A total of 88 compounds ...
Eremophilane-type sesquiterpenes from Ligularia hodgsonii: isolation, structural characterization, and pro-angiogenic potential [0.03%]
莱叶黄花蒿中裂环环烯醚萜类成分的分离、结构鉴定及促血管生成活性研究
Zhenhua Wan,Huilin Peng,Chunping Tang et al.
Zhenhua Wan et al.
A comprehensive chemical investigation of the rhizomes and roots of Ligularia hodgsonii Hook. was undertaken, which resulted in the identification of 11 previously undescribed eremophilane-type sesquiterpenes (1-4, 7-12, and 14), in additio...
Yu Zhang,Yu-Chen Zhang,Yu-Chen Fan et al.
Yu Zhang et al.
From the rhizomes of Paris polyphylla var. yunnanensis (Franch.) Hand.-Mazz., five novel steroidal saponins (Polyphyllozsides A-E, 1-5) and four known steroidal saponins (6-9) were isolated. The biological activities of the nine compounds a...
Chloro-containing polyketides with anti-neuroinflammatory and anti-angiogenic activities from a coralline algicolous fungal strain Diaporthe middletonii Km3279 [0.03%]
产于珊瑚藻的真菌Diaporthe middletonii Km3279中的含氯聚酮及其抗神经炎症和抗血管生成活性研究
Yi-Fei Liao,George Hsiao,Shih-Wei Wang et al.
Yi-Fei Liao et al.
In this study, a fungal strain Diaporthe middletonii Km3279, was isolated from the coralline alga Corallina declinata collected in Lieyu Township, Kinmen County, Taiwan, and subsequently identified. Liquid fermentation was carried out using...
Undescribed triterpenoid saponins from the leaves of Astragalus membranaceus (Fisch.) Bge. and their neuroprotective effects [0.03%]
一种新的膜荚黄芪叶三萜皂苷及其神经保护作用
Wenxiang Xu,Qian Zhang,Xinyuan Li et al.
Wenxiang Xu et al.
In total, 14 undescribed triterpenoid saponins (1-14), along with three known ones (15-17), were isolated from the leaves of Astragalus membranaceus (Fisch.) Bge.. In the case of previously unknown compounds, it was observed that dehydratio...
Discovery of and mechanistic insights into anti-inflammatory sesquiterpenoids from flowers of Inula japonica Thunb [0.03%]
日本矮蓬蒿花的抗炎倍半萜及其活性机制研究
Trung Huy Ngo,Ngoc Duy Le,Kibria Gulam et al.
Trung Huy Ngo et al.
Flowers of Inula japonica Thunb., a rich source of sesquiterpenoids, have long been used in traditional medicine to improve inflammatory conditions. To explore previously unreported anti-inflammatory sesquiterpenoids, isolation and structur...
Natural cadinane-type sesquiterpenoids and their bioactivity: a review (2015-2025) [0.03%]
natura_cadinane_型倍半萜类化合物及其生物活性研究（2015—2025）
Sheng-Zhi Wang,Hong Zhu,Xiao-Po Zhang et al.
Sheng-Zhi Wang et al.
Natural cadinene-type sesquiterpenoids (CTSs) exhibit diverse structures and a wide range of pharmacological activities, including anti-tumor, anti-inflammatory, and antibacterial effects. They represent an important source for new drug dis...
Dibenzocyclooctadiene lignans from Kadsura coccinea and their immunosuppressive activities [0.03%]
紫花地不容中分离得到的茋木脂素类化合物及其免疫抑制活性研究
An Jin,Zhuocan Huang,Hui Li et al.
An Jin et al.
A detailed phytochemical analysis of the dried, ripe fruits of Kadsura coccinea led to the isolation and structural characterization of eleven undescribed lignans, designated kadcolignan K-U (1-11), together with thirteen previously documen...
Guaianolide sesquiterpenoids from Chrysanthemum indicum L. alleviate rheumatoid arthritis by targeting of NLRP3 inflammasome pathway [0.03%]
牻牛儿菊素类倍半萜化合物通过靶向NLRP3炎性小体通路治疗类风湿关节炎作用机制研究
Gui-Min Xue,Hao Feng,Dong-Rong Zhu et al.
Gui-Min Xue et al.
Thirteen undescribed guaianolide lactones chryguaialactones A-M (1-13), together with ten known analogues (14-23), were isolated from the flowers of Chrysanthemum indicum L. The previously unreported structures including their absolute conf...