A Ratiometric genetically encoded fluorescent probe for ultrasensitive and self-calibrated detection of Hg2 [0.03%]
一种比率型遗传编码荧光探针用于Hg²⁺的超灵敏自校准检测
Dan Wang,Zixin Wu,Tianyu Song et al.
Dan Wang et al.
Mercury ion (Hg2+) pollution poses severe environmental and health risks, necessitating the development of highly sensitive and reliable detection methods. Although ratiometric and genetically encoded fluorescent probes each offer distinct ...
Construction of BSA-CuNCs@UiO-66 nanoprobe based on MOF confinement effect and its ultrasensitive fluorescence sensing for creatinine [0.03%]
基于MOF限制效应的BSA-CuNCs@UiO-66纳米探针构建及其超灵敏荧光检测创inine性能研究
Lian-Lian Duan,Wen-Jun Liu,Rui Zhai et al.
Lian-Lian Duan et al.
This study employed a pore-confined synthesis strategy to achieve the in situ growth of bovine serum albumin-capped copper nanoclusters (BSA-CuNCs) within the UiO-66 framework (BSA-CuNCs@UiO-66). This nanocomposite enables highly sensitive ...
A novel amide-quinoline salt-based mitochondrial-targeted fluorescent probe for detecting pH in cells and water samples [0.03%]
一种新型酰胺-喹啉盐类线粒体靶向荧光探针用于检测细胞和水样中的pH值
Feng-Ting Liu,Bang-Zhao Zhou,Jun-Ying Miao et al.
Feng-Ting Liu et al.
Mitochondria is the primary organelle responsible for energy production, and their weakly alkaline microenvironment (pH ≈ 8) is closely linked to cellular metabolism and disease states. Mitochondrial acidification is closely associated wit...
Exploring the use of FTIR Amide I band deconvolution to investigate protein secondary structure and texturisation during high moisture extrusion [0.03%]
探讨FTIR酰胺I带分解用于研究高水分挤压过程中蛋白质二级结构及质构化的影响
Clara Barnés-Calle,Pere Gou,Elena Fulladosa et al.
Clara Barnés-Calle et al.
Fourier transform infrared spectroscopy (FTIR) combined with Amide I band deconvolution has been used to investigate protein structural changes occurring during high moisture extrusion processing (HMEP). However, it is a sensitive, user-dep...
Deciphering functional redundancy of lysine decarboxylases in probiotic E. coli Nissle 1917 via an integrated CRISPR-FTIR phenomics platform [0.03%]
基于CRISPR-FTIR表型组学平台解析益生菌E.coli Nissle 1917中赖氨酸脱羧酶的功能冗余性
Yiqing Zhang,Mingyu Wu,Feng Geng et al.
Yiqing Zhang et al.
Fourier transform infrared (FTIR) microspectroscopy is a rapid, label-free tool for microbial metabolic phenotyping. Here, we integrate synchrotron-based FTIR microspectroscopy with CRISPR-Cas9 editing to decipher the functional redundancy ...
Advanced spectral modeling for bacterial strains: A MARS-PLS2 approach with Lasso regularization and baseline optimization [0.03%]
先进的细菌菌株光谱建模：带Lasso正则化和基线优化的MARS-PLS2方法
Sughra Sarwar,Tahir Mehmood,Mudassir Iqbal
Sughra Sarwar
The natural characteristics of the infrared spectroscopic data are that it tends to distort the baseline, there is high-dimensionality and non-linear correlation that hinder reliable prediction of biochemical properties. To overcome these o...
Progress of stimuli-responsive fluorescent materials with time-dependent optical properties for information anti-counterfeiting and encryption [0.03%]
具有时间依赖性光学性能的刺激响应荧光材料在信息防伪加密领域中的进展
Qi Zhang,Guoxin Liu
Qi Zhang
Information security and anti-counterfeiting technologies are facing increasingly severe challenges worldwide. Traditional static anti-counterfeiting methods, being relatively easy to replicate, are gradually becoming inadequate to meet hig...
Effect of proton therapy and chemoradiotherapy on biochemistry of radioresistant prostate cancer cells studied by Raman microspectroscopy [0.03%]
拉曼显微光谱法研究质子治疗和化学放疗对放射抵抗性前列腺癌细胞生化特性的影响
Maciej Roman,Tomasz P Wrobel,Agnieszka Panek et al.
Maciej Roman et al.
Radiotherapy is an effective type of anticancer treatment due to its localized impact and fewer side effects. Nowadays, proton therapy has become a more common choice than photon-based radiotherapy due to its advantages, including independe...
Detection of hazelnut rancidity inside chocolate tablets using near-infrared hyperspectral imaging [0.03%]
基于近红外高光谱成像的巧克力板中杏仁氧化检测技术
Jokin Ezenarro,Núria Vera-I-Valls,Ángel García-Pizarro et al.
Jokin Ezenarro et al.
Near-infrared hyperspectral imaging (NIR-HSI) was evaluated as a non-destructive tool to detect hazelnut rancidity directly inside commercial chocolate bars, without separating the nuts from the chocolate matrix. Chocolate bars containing f...
SERS-based quantitative detection of furfural in transformer oil using an improved residual network and transfer learning [0.03%]
基于改进残差网络和迁移学习的变压器油中糠醛定量检测（SERS法）
Xia Jie
Xia Jie
Accurate quantification of furfural concentration in transformer oil is crucial for assessing the aging status of insulating paper; however, conventional quantitative models face significant challenges in generalizing due to interference fr...