Multi-wavelength photobleaching kinetics of endogenous fluorophores for label-free tissue characterization with potential for tumor margin estimation using machine learning [0.03%]
基于机器学习的肿瘤边界估计的无标签组织表征的内源性荧光分子多波长光漂白动力学研究
Siddharth Pal,Hemant Krishna,Srinibas Satapathy et al.
Siddharth Pal et al.
Autofluorescence photobleaching encodes valuable information related to tissue morphology, metabolism, and fluorophore microenvironment; however, it remains mostly underexplored as a quantitative imaging biomarker. This study investigates m...
Spectroscopic insight into solvent-dependent self-assembly and supramolecular chirality inversion of an atypical bola-type chiral conjugated gelator [0.03%]
基于溶剂的手性反转及超分子手性的不对称双锥型凝胶剂的光谱研究
Yuxin Ren,Meiyu Jia,Cai-Cai Zhang et al.
Yuxin Ren et al.
A linear bola-type chiral conjugated gelator incorporating a naphthalene core, ethynyl linkers, and terminal chiral amide groups was designed and synthesized to investigate the spectroscopic features of solvent-dependent self-assembly and s...
Macromolecular characterization of basal cell carcinoma using ATR-FT-IR spectroscopy combined with machine learning [0.03%]
结合机器学习的ATR-FT-IR光谱法表征基底细胞癌中的大分子特征
Zozan Guleken,Caglar Uyulan,Hacer Ahsen Yıldırım et al.
Zozan Guleken et al.
Background: Basal cell carcinoma (BCC) is the most common human malignancy, yet its diagnosis relies on invasive histopathological biopsy with considerable inter-observer variability. Attenuated Total Reflectance Fourier ...
Based on window function optimization and DFT verification to establish terahertz fingerprint of triphenyl phosphate for non-destructive analysis [0.03%]
基于窗函数优化和DFT验证的非破坏性分析茋磷酸酯特征指纹图谱的建立
Jing Su,Luyao Zhao,Mingzhang Guo et al.
Jing Su et al.
Triphenyl phosphate (TPHP), an emerging pollutant with neurotoxic and reproductive toxicity, severely threatens global food safety and human health through environmental exposure risks and bioaccumulation. A rapid and non-destructive detect...
Super-resolution imaging with a mitochondria-targeted fluorescent probe: Evaluation of chemotherapy-induced hepatorenal injury [0.03%]
线粒体靶向荧光探针超分辨率成像在化疗诱导的肝肾损伤评估中的应用
Haiying Zhu,Weikang Peng,Lin Hu et al.
Haiying Zhu et al.
With the rising global incidence of cancer, anticancer drugs including cisplatin (DDP) and sunitinib (SU) are being widely used in clinical practice. However, severe nephrotoxicity of DDP and prominent hepatotoxicity of SU drastically restr...
Simultaneous detection and degradation of the lipid antioxidant propyl gallate using a Fe-MOF@UiO-66 bifunctional nanozyme [0.03%]
一种Fe-MOF@UiO-66双功能纳米酶同时用于脂质抗氧化剂棓丙酯的检测与降解
Ning Li,Suhuan Liu,Yifei Zhang et al.
Ning Li et al.
Propyl gallate (PG) is a widely used food antioxidant that prevents oxidation and extends shelf life. However, excessive intake of PG poses potential health risks, making its accurate detection and control crucial for food safety. In this s...
Polyhedral MgMn2O4 oxide nanozyme based for visual detection of epinephrine [0.03%]
用于肾上腺素视觉检测的多面体MgMn2O4纳米酶基氧化物
Zhifan Li,Yi Ke,Tiantao Chen et al.
Zhifan Li et al.
Polyhedral MgMn₂O₄ nanozymes were synthesized through a solvothermal route followed by high-temperature calcination. Their particle size and morphology were precisely tailored by varying the precursor concentration. Decreasing the precurs...
Tuning optical properties, charge transfer and anticancer activity of curcumin-cyanine conjugates: A combined experimental and DFT study [0.03%]
结合实验和DFT调谐姜黄素-青花素共轭物的光学性质、电荷转移及抗癌活性
Jafar Alkabli,Khalid Althumayri
Jafar Alkabli
Despite curcumin's potential for photosensitizer design, its low stability in the aqueous phase and lack of charge-transfer properties have prevented its application in photodynamic therapy (PDT). We rationally designed four curcumin-monome...
Ultrasensitive and deployable carbon dots-loaded PVP nanofibrous membranes for enhanced fluorescence-based atrazine detection in water [0.03%]
一种用于水基阿特拉津增强型荧光检测的超灵敏且可部署的PVP碳点纳米纤维素膜
Pooja Chauhan,Krishna Priyadarshini Das,Bhabani K Satapathy
Pooja Chauhan
Atrazine, a synthetic herbicide from the triazine family, is found to be the most harmful and commonly detected organic pollutant in surface and groundwater. Therefore, there is an increasing demand for sensing platforms that are portable, ...
Biophysical insights into interaction mechanism of cediranib with human serum albumin: In-vitro and in-silico perspectives [0.03%]
Cediranib与人血清白蛋白相互作用的生物物理机制见解：离体和分子模拟视角
Md Zahirul Kabir,Cem Erkmen,Fazal Rehman et al.
Md Zahirul Kabir et al.
Cediranib (CB), a tyrosine kinase inhibitor, exhibits encouraging anticancer activity against breast, prostate, glioblastoma, and non-small cell lung cancer cells. This study used multi-spectral and computational analyses to elucidate the b...