Corrigendum to "Enhanced uranium sequestration through selenite-modified nano-chitosan loaded with melatonin: Facilitating U(IV) conversion". [Int. J. Pharm. 662 (2024) 124502] [0.03%]
Jingxuan Lu,Juan Li,Shiyan Fu et al.
Jingxuan Lu et al.
Next-generation polymer-based nanofiber ocular inserts: fabrication innovations, therapeutic applications, regulatory perspectives, and future directions [0.03%]
Giriraj Pandey,Tejaswini Kolipaka,Deepankar Yadav et al.
Giriraj Pandey et al.
The intricate architecture and physiology of the eye present ocular drug delivery with a significant challenge, resulting in restricted drug absorption and an insufficient therapeutic impact. Conventional delivery systems, however, fail to ...
Single-cell probiotic encapsulation with a sandwich-structured nanocoating for intestinal-targeted delivery and inflammatory-responsive drug release [0.03%]
Xuan Gu,Yunchao Wu,Jiaying Liu et al.
Xuan Gu et al.
Surface-engineered probiotics represent a promising therapeutic strategy for treating ulcerative colitis (UC). However, their therapeutic efficacy is often compromised by the complex pathological conditions and limited drug integration capa...
Hyaluronan-cholesterol core-shell glycerosomes: Innovative nanocarriers for mitigating smoke-induced oxidative stress and inflammation in the lungs [0.03%]
Matteo Aroffu,Pietro Matricardi,Chiara Di Meo et al.
Matteo Aroffu et al.
Lungs are constantly exposed to environmental stressors, such as cigarette smoke, which can lead to oxidative stress and inflammation, contributing to the development of chronic lung diseases. To mitigate these conditions, innovative lipid-...
Enhancing effect and safety assessment of borneol on the oral absorption of sub-100 nm PLGA nanoparticles [0.03%]
Qin Luo,Ge Ru,Tianci Hu et al.
Qin Luo et al.
Overcoming the gastrointestinal barrier remains a major challenge for oral nanoparticle (NP) drug delivery systems. Here, we evaluate borneol as a permeation enhancer for improving the oral absorption of intact poly(lactic-co-glycolic acid)...
Jakub Kwiatek,Magdalena Paczkowska-Walendowska,Anna Rył et al.
Jakub Kwiatek et al.
This study aimed to create and benchmark azithromycin-loaded chitosan composite films optimized for oral regenerative surgery using a systematic 32 design-of-experiments (DoE) model. Nine formulations (CS LMW/MMW/HMW; 1-3% gelatin; 1-3% gly...
A dynamic in vitro model of blood-brain barrier: effect of different polymeric nanoparticles on the crossing ability [0.03%]
Teresa Barra,Marco Bellotti,Michele Conti et al.
Teresa Barra et al.
The blood-brain barrier (BBB) remains a critical bottleneck for Central Nervous System (CNS) drug delivery. While polymeric nanoparticles (NPs) are promising carriers, their development requires advanced screening platforms. This work focus...
A predictive release kinetic model guiding the rational design of sustained release solid dispersions with insoluble carriers [0.03%]
Kai Ge,Yuanhui Ji
Kai Ge
Flurbiprofen (FBU) is a nonsteroidal anti-inflammatory drug with short half-life, requiring frequent dosing and leading to potential gastrointestinal side effects. To address these limitations, this study aimed to develop the FBU sustained ...
Functionalised mesoporous silica with stearic acid: A novel approach to improve octreotide delivery [0.03%]
Mohamad Anas Al Tahan,Craig Russell,Ali Al-Khattawi
Mohamad Anas Al Tahan
Oral peptide delivery remains challenging due to poor intestinal permeability and low bioavailability. Mesoporous silica have gained attention as drug carriers due to their high loading capacity and tuneable surface properties. This study i...
Alaa Ibrahim,Maha Nasr
Alaa Ibrahim
Exosomes are pivotal biological entities implicated in both pathogenesis and treatment of various dermal disorders. Their unique structure comprising intracellular proteins, growth factors, and diverse nucleic acids such as mRNA and siRNA e...