Alise J Ponsero,Basak Bahcivanci,Antonietta Hayhoe et al.
Alise J Ponsero et al.
Across the human lifespan, the gut microbiome exhibits considerable inter-individual variation. However, individuals within the same age group often share characteristic compositional and functional patterns shaped by factors such as early ...
Epigenetic blind spots - the role of DNA methylation dynamics in stem cell-based models of embryogenesis [0.03%]
表观遗传的盲点-胚胎发生干细胞模型中DNA甲基化的作用
Sara Canil,Anna Corrà,Annalisa Scapolatiello et al.
Sara Canil et al.
Embryo-like structures, or stembryos, complement embryo research in innovative ways and provide an alternative when embryo utilization is ethically or technically limited. These models, however, are hindered by experimental variability and ...
Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration [0.03%]
残余尾扭转通过不对称肌原纤维的稳定来抵抗端芽ascidians幼体对双边对称性重建
Yuki S Kogure,Misaki K Nishio,Satoru Okuda et al.
Yuki S Kogure et al.
Left-right (L-R) symmetry is a fundamental feature of bilaterian body plans, yet how it is actively maintained and corrected during development remains poorly understood. In the ascidian Ciona, embryos transiently exhibit clockwise tail twi...
Stavros Azinas,Marta Carroni
Stavros Azinas
AAA+ ATPases safeguard proteostasis by harnessing ATP hydrolysis to unfold misfolded or damaged proteins. Depending on their specific structural motifs and partners, they either channel substrates to peptidases for degradation or disentangl...
Xuelang Mu,Ampon Sae Her,Tamir Gonen
Xuelang Mu
Cells rely on metabolic control; the mechanistic target of rapamycin complex 1 (mTORC1) senses nutrient availability, particularly amino acids. Lysosomes maintain amino acid homeostasis through recycling. SLC38A9, a lysosomal amino acid tra...
Unique SNPs in the promoter of the peptide transporter gene PTR2 increase its expression in the Saccharomyces cerevisiae sake strain [0.03%]
存在于清酒酵母肽运输蛋白PTR2启动子区的特异性SNPs提高了PTR2表达量
Nanami Nakagawa,Kenji Kitamura
Nanami Nakagawa
Although the mechanism of action of the tripeptide-like herbicide bialaphos is well understood, its cellular uptake process remains elusive. We report that a peptide transporter mediates its uptake in Saccharomyces cerevisiae. The Japanese ...
RETRACTION: Down-Regulation of Adenine Nucleotide Translocase 3 and Its Role in Camptothecin-Induced Apoptosis in Human Hepatoma QGY7703 Cells [0.03%]
撤回：腺苷酸转运蛋白3下调及其在喜树碱诱导的肝癌QGY7703细胞凋亡中的作用
Z. Hu , X. Guo , Q. Yu , L. Qiu , J. Li , K. Ying , C. Guo and J. Zhang , "Down-Regulation of Adenine Nucleotide Translocase 3 and Its Role in Camptothecin-Induced Apoptosis in Human Hepatoma QGY7703 Cells," FEBS Letters 583, no. 2 (2009): ...
Organizing the interface-Plasma membrane architecture and receptor dynamics in virus-cell interactions [0.03%]
组织界面-病毒与细胞相互作用中的质膜结构和受体动力学
Jan Schlegel,Christian Sieben
Jan Schlegel
Plasma membranes are organized into dynamic nanoscale domains that regulate lipid and protein distribution, diffusion, and receptor availability. Because viruses act on similar length scales, this organization shapes early infection steps, ...