RETRACTION: MicroRNA-106b Regulates the Tumor Suppressor RUNX3 in Laryngeal Carcinoma Cells [0.03%]
撤稿：微小核糖核酸-106b通过调节喉癌细胞肿瘤抑制蛋白RUNX3表达发挥促凋零作用
Y. Xu, K. Wang, W. Gao, C. Zhang, F. Huang, S. Wen and B. Wang, "MicroRNA-106b Regulates the Tumor Suppressor RUNX3 in Laryngeal Carcinoma Cells," FEBS Letters 587, no. 19 (2013): 3166-3174, https://doi.org/10.1016/j.febslet.2013.05.069. Th...
An epithelial GPR35 isoform supports tumor-associated transcriptional and metabolic phenotypes [0.03%]
一种上皮GPR35同种型支持肿瘤相关转录和代谢表型
Jørgen D Rønneberg,Martine Hjeltnes,Josephine Krieger et al.
Jørgen D Rønneberg et al.
G protein-coupled receptor 35 (GPR35) has been implicated in cancer, but the functional roles of its isoforms remain unresolved. Here, we characterize GPR35-long, an N-terminally extended epithelial isoform selectively enriched in colorecta...
Loss of LipT2 disrupts mitochondrial protein lipoylation and metabolic homeostasis in Drosophila melanogaster [0.03%]
果蝇LipT2丧失导致线粒体蛋白脱辅基和代谢稳态失调
Yoshihito Kishita,Manabu Tsuda,Yukiko Sato-Miyata et al.
Yoshihito Kishita et al.
Lipoic acid is an essential cofactor for mitochondrial multienzyme complexes involved in central metabolism. In humans, mutations in the lipoyl transferase LIPT2 impair mitochondrial protein lipoylation and cause severe metabolic disease. H...
From outflow tract development to ventriculo-arterial discordance - Developmental and genetic mechanisms of d-TGA and ccTGA [0.03%]
流出道发育到心室流出道连接异位：大动脉转位（d-TGA）和永存左上腔静脉型大动脉转位（ccTGA）的发育及遗传机制
Ségolène Bernheim,Marine Tortigue,Stanislao Igor Travisano et al.
Ségolène Bernheim et al.
Discordant ventriculo-arterial (VA) connection characterizes dextro-transposition of the great arteries (d-TGA) and congenitally corrected transposition of the great arteries (ccTGA). These distinct defects involve overlapping developmental...
The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases [0.03%]
铁离子螯合剂治疗神经退行性疾病的机会与陷阱
Barry Halliwell
Barry Halliwell
There is considerable evidence that iron accumulation in the affected brain regions plays a role in the pathology of neurodegenerative diseases, probably because of the ability of iron ions to promote oxidative damage to important biomolecu...
AscF in the mycobacterial CIII-CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration [0.03%]
麻风分枝杆菌CIII-CIV超级复合物中的AscF不含金属和核苷酸，但可将苹果酸氧化与呼吸相联系
Eni Rile,Riccardo Diamanti,Daniel Lundin et al.
Eni Rile et al.
In most Actinobacteria, the respiratory complexes CIII and CIV form an obligate supercomplex, but the exact subunit composition varies. Here, we have characterized AscF (MSMEG_4692), a subunit of the Mycobacterium smegmatis CIII-CIV superco...
A call for unified use of human aminoacyl-tRNA synthetase (ARS) gene nomenclature [0.03%]
关于统一使用人类氨酰-tRNA合成酶（ARS）基因符号的建议
Anthony Antonellis,Maximiliano Barrientos,Eva Bensasson et al.
Anthony Antonellis et al.
Aminoacyl-tRNA synthetases (ARSs) are a family of enzymes that attach amino acids to tRNAs. To date, all 37 human ARS genes have been implicated in genetic diseases, affecting over a thousand patients worldwide. At the 2025 Federation of Eu...
Editorial
FEBS letters. 2026 Jul 21. DOI:10.1002/1873-3468.70418 2026
Proteasomes in extracellular vesicles-Emerging roles in cancer progression and intercellular communication [0.03%]
细胞外囊泡中的蛋白酶体在癌症进展和细胞间通讯中的新兴作用
Irina Viktorovna Kondakova,Natalia Valerievna Yunusova,Evgenia Alexandrovna Sidenko et al.
Irina Viktorovna Kondakova et al.
Intercellular communication via extracellular vesicles (EVs) is a means by which cells exchange various molecules, including proteins, protein complexes, lipids, nucleic acids, and others. This communication is essential for cellular adapta...
Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach [0.03%]
植物线粒体OrfX蛋白的鉴定：一种质谱方法
Matthias Döring,Jan de Jonge,Hans-Peter Braun et al.
Matthias Döring et al.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a protein classified as very rare and which has so far escaped mass spectrometric detection. The protein resembles the c-subunit of bacterial twin-argini...
Direct interaction between tubulin and PMCA, a complex with functional implications [0.03%]
微管蛋白与PMCA的直接相互作用及其功能意义
Gustavo Caro,Melisa M Balach,Alexis N Campetelli et al.
Gustavo Caro et al.
Tubulin exerts regulatory functions through interactions with various noncytoskeletal proteins, modulating their activity and contributing to diverse cellular processes. Here, we investigated the direct interaction between tubulin and plasm...