A novel histidine-acetate buffer for freeze-dried monoclonal antibody formulations [0.03%]
一种组氨酸-乙酸盐缓冲液用于单克隆抗体冻干粉制剂
Jia-Yi Lv,Han Gao,Huan-Fang Xie et al.
Jia-Yi Lv et al.
Histidine (His)-hydrochloride (HCl) is widely used in freeze-dried monoclonal antibody (mAb) formulations, but alternative buffers are required when chloride ions are undesirable. This study evaluates His-acetate (Ac) as a substitute and it...
Naproxen printlets for extemporaneous dispersion: Designing new medicines for drug delivery through the enteral route [0.03%]
萘普生打印片用于现配现用制剂:通过肠通路给药设计新药物
Nadine Lysyk Funk,Flávia Carvalho Tavaniello,Edilson Valmir Benvenutti et al.
Nadine Lysyk Funk et al.
Off-label use of medicines administered via enteral feeding tubes (EFT) can lead to dose inaccuracies, adverse effects and tube obstruction, compromising therapeutic outcomes. Thus, new manufacturing processes are required to design medicin...
Paclitaxel and rose bengal loaded microbubbles for the ultrasound targeted chemo-sonodynamic therapy of pancreatic cancer [0.03%]
载有紫杉醇和玫瑰精的微气泡用于胰腺癌超声造影介导的化疗与声动力联合治疗
Jack Wright,Keiran Logan,Thomas McKaig et al.
Jack Wright et al.
Despite significant advances in cancer treatment over the past five decades, survival outcomes for pancreatic cancer have remained largely unchanged. The effectiveness of chemotherapy as a treatment for pancreatic cancer is limited by the d...
N-acetylcysteine loaded electrospun core/shell nanofibers: a promising system for ferroptosis in spinal cord injury [0.03%]
负载N-乙酰半胱氨酸的电纺芯壳纳米纤维:脊髓损伤中铁死亡的潜在系统
Meliha Gunes,Gizem Kaftan Öcal,Bünyamin Kılıclı et al.
Meliha Gunes et al.
Spinal cord injury (SCI) induces a cascade of secondary damage mechanisms, including oxidative stress, inflammation, and cell death, which severely impair neuronal recovery. In this study, N-acetylcysteine (NAC), a thiol-based antioxidant w...
Does slowly reversible binding to keratin contribute to stratum corneum reservoir function? [0.03%]
角蛋白上的缓慢可逆结合对皮脂膜库功能的贡献作用探讨?
Abigail M Poehls,Johannes M Nitsche,Gerald B Kasting
Abigail M Poehls
The existence of a storage capacity or reservoir function within human stratum corneum (HSC) for topically applied chemicals is well documented. However, the source of this reservoir remains ambiguous and may well depend on the chemical and...
In vitro two stage one compartment dumping test data and absorption/formulation PBBM modeling to explain a bioequivalence failure of valsartan formulations [0.03%]
基于体外两阶段一室倾泻试验数据和吸收/处方PBBM建模解释缬沙坦制剂的生物等效性失败的原因
Bárbara Sánchez-Dengra,Alejandro Ruiz-Picazo,Isabel Gonzalez-Alvarez et al.
Bárbara Sánchez-Dengra et al.
Background: In recent years, significant efforts have been made to develop new dissolution methods capable of predicting the in vivo behavior of pharmaceutical formulations. This is essential for establishing valid in vit...
Corrigendum to "Enhancement in site-specific delivery of carvacrol for potential treatment of infected wounds using infection responsive nanoparticles loaded into dissolving microneedles: A proof of concept study." [Eur. J. Pharm. Biopharm. 147 (2020) 57-68] [0.03%]
关于“使用感染响应型纳米颗粒负载的可溶性微针递送百里酚增强感染伤口的治疗:概念验证研究”的勘误[ Eur. J. Pharm. Biopharm. 147 (2020) 57-68]
Maria Mir,Andi Dian Permana,Naveed Ahmed et al.
Maria Mir et al.
Corrigendum to "Dissolving microneedle-mediated dermal delivery of itraconazole nanocrystals for improved treatment of cutaneous candidiasis". [Eur. J. Pharm. Biopharm. 154 (2020) 50-61] [0.03%]
有关“伊曲康唑纳米晶体溶解微针给药对皮肤念珠菌病治疗的改善作用”的勘误页[Eur. J. Pharm. Biopharm. 154 (2020) 50-61]
Andi Dian Permana,Alejandro J Paredes,Fabiana Volpe-Zanutto et al.
Andi Dian Permana et al.
Corrigendum to "Dissolvable microarray patches of levodopa and carbidopa for Parkinson's disease management" [Eur. J. Pharm. Biopharm. 199 (2024) 114304] [0.03%]
关于“用于帕金森病管理的左旋多巴和卡比多巴可溶解微阵列贴片”的勘误说明[Eur. J. Pharm. Biopharm. 199 (2024) 114304]
Qonita Kurnia Anjani,Natalia Moreno-Castellanos,Yaocun Li et al.
Qonita Kurnia Anjani et al.
Corrigendum to "Repeat application of microneedles does not alter skin appearance or barrier function and causes no measurable disturbance of serum biomarkers of infection, inflammation or immunity in mice in vivo" [Eur. J. Pharm. Biopharm. 117 (2017) 400-407] [0.03%]
“微针的重复应用不会改变皮肤外观或屏障功能,并且对小鼠体内感染、炎症或免疫的血清生物标志物没有可测量的干扰作用”的勘误(英文原文发表在 Eur. J. Pharm. Biopharm. 117 (2017) 400-407)
Eva M Vicente-Perez,Eneko Larrañeta,Maelíosa T C McCrudden et al.
Eva M Vicente-Perez et al.